Experimental and Clinical Psychopharmacology
June 25, 2018
Lais Fernanda Berro, Hannah Shields, Melis Odabas-Geldiay et al.
6 citations
(-) MDMA (0.3, 1.0, or 1.7 mg/kg) at 9 or 16 h (3 h before "lights off"). Morning treatments had no effects on sleep-like parameters. Racemic MDMA decreased general daytime activity during the first hour after injection and increased daytime activity at 3 hr posttreatment. Although afternoon administration of racemic MDMA increased sleep latency, it improved other sleep parameters, decreasing...
Behavioural Processes
September 22, 2014
Tathiana A. Alvarenga, Daniel Ninello Polesel, Gabriela Matos et al.
10 citations
The ingestion of the beverage Ayahuasca usually occurs in religious ceremonies that are performed during the night leading to sleep deprivation. The purpose of the present study was to characterize the acute effects of Ayahuasca upon the sexual response of sleep deprived male rats. One group of sexually experienced male Wistar rats were submitted to a paradoxical sleep deprivation (PSD)...
Drug and Alcohol Dependence
November 1, 2011
Roberta Procópio-Souza, Daniela F Fukushiro, Thaís F Trombin et al.
Behavioral sensitization in rodents is hypothesized to reflect neuronal adaptations that are related to drug addiction in humans. We evaluated the effects of group exposure on the acute hyperlocomotion and behavioral sensitization induced by four drugs of abuse in C57BL/6 mice: methylenedioxymethamphetamine (MDMA), d-amphetamine, morphine and ethanol. In the priming session, animals received an...
Addiction Biology
January 2010
Tathiana A. Alvarenga, Mônica L. Andersen, Daniel A Ribeiro et al.
We evaluated the overall genetic damage induced by different doses of cocaine and MDMA (3,4-Methylenedioxymethamphetamine) in several organs. One hour after intraperitoneal drug administration, mice were euthanized; peripheral blood, liver and brain were collected, and the cellular suspensions were used for the single cell gel (comet) assay. We determined that all doses of cocaine and MDMA...