BACKGROUNDEvidence for adjunctive subanesthetic-dose esketamine during electroconvulsive therapy (ECT) in adolescents with major depressive disorder (MDD) is limited.Suicidal ideation is a critical early treatment target in this population.We hypothesized that adjunctive subanesthetic-dose esketamine during ECT would accelerate the reduction in suicidal ideation and improve early clinical...
BACKGROUND Lower extremity arteriosclerotic occlusive disease (LEAOD) is a prevalent chronic vascular condition that significantly increases the risk of lower limb dysfunction and depressive symptoms. Mindfulness-based interventions have demonstrated efficacy in improving mood and coping ability in patients with various chronic illnesses; however, their specific impact on the dual burden of...
BACKGROUNDPerimenopausal women are vulnerable to both sleep disturbances and depressive symptoms.Mindfulness has been associated with better psychological well-being and sleep outcomes, but the specific psychological pathway linking mindfulness to sleep quality in this population remains insufficiently defined.In particular, it remains unclear whether depressive symptoms represent an...
BACKGROUND Patients undergoing peritoneal dialysis (PD) frequently experience anxiety and sleep disturbances.However, the comparative efficacy of psychological interventions on these symptoms remains unclear.AIM To compare the efficacy of mindfulness-based cognitive therapy (MBCT) and routine psychological support (PS) on anxiety symptoms and sleep quality in patients undergoing PD.METHODS This...
BACKGROUND Anxiety and depression are prevalent and often co-occurring mental health disorders. While mindfulness training has shown efficacy in reducing symptoms, the underlying mechanisms, particularly the role of psychological resilience, remain underexplored. This study investigates whether mindfulness training alleviates anxiety and depression and hypothesizes that psychological resilience...
BACKGROUND Schizophrenia is a chronic mental disorder, which affects about 0.75% of the global population. Most patients show negative symptoms and cognitive impairment, and often accompanied by anxiety and depression. These persistent negative emotions significantly impair the treatment compliance, functional recovery and quality of life of patients. Although mindfulness-based stress reduction...
Schizophrenia is associated with marked abnormalities in consciousness, specifically in the interplay between implicit and explicit cognitive processing.However, whether these deficits originate from early sensory degradation or late-stage access failures remains heavily debated.This narrative review synthesizes psychophysical, electrophysiological, and neuroimaging literature to evaluate these...
BACKGROUND Post-traumatic stress disorder (PTSD) is a common psychological complication after radical lung cancer surgery and has a significant impact on postoperative recovery and quality of life. Esketamine, a new anesthetic agent, may be protective against postoperative PTSD through modulation of neurotransmitter systems and anti-inflammatory actions. AIM To explore the underlying mechanisms...
Patients who undergo radical cervical cancer surgery often experience sexual dysfunction and psychological distress, which seriously affects their quality of life. This study aimed to evaluate the clinical effectiveness of mindfulness-based stress reduction (MBSR) therapy for psychosexual adaptation in patients after radical cervical cancer surgery. To systematically evaluate the clinical...
Background: Treatment-resistant depression (TRD) has a poor response to clinical treatment. Patients with TRD do not respond adequately to standard antidepressants. Even after receiving a full dose and sufficient duration of combined antidepressant therapy, significant improvement is still difficult to achieve. At present, electroconvulsive therapy (ECT) remains a clinically effective method...
Emergency department nurses face severe occupational stress leading to anxiety, depression, and burnout, which significantly impair their well-being and patient-care quality. This narrative review examined the role of mindfulness-based stress reduction (MBSR) in addressing these challenges. Rooted in nonjudgmental present-moment awareness, MBSR enhances emotional regulation and reduces...
Selfishness, understood as excessive focus on the self, appears to be a predominant feature of contemporary culture. While the degree of self-focus is adaptive for survival and decision-making, self-rigidity has been associated with significant psychological, interpersonal, and social costs. Throughout history, philosophers, religious leaders, and social activists have promoted a "hypo-egoic"...
This letter discusses the study by Liu et al recently published in World Journal of Psychiatry, which examines the benefits of combining epirubicin (EPI) with mindfulness interventions for patients with urinary system tumors and depression. The study included 110 patients and compared an experimental group receiving EPI and a mindfulness intervention strategy with a control group treated with...
Delirium is a transient and acute syndrome of encephalopathy, characterized by disturbances in consciousness, orientation, cognition, perception, and emotional regulation, often accompanied by hallucinations, illusions, psychomotor agitation, and restlessness. Postoperative delirium (POD), a common complication particularly in elderly patients, significantly impacts recovery by prolonging...
World Journal of PsychiatryApril 19, 2025Carmen Borrás-sansaloni, Marina Ricco-Pérez, Antoni Mayol et al.1 citation
Psychotic disorders are characterized by both positive symptoms (hallucinations, delusions) and negative symptoms (emotional blunting, anhedonia) that impair daily functioning. While antipsychotic drugs and psychological interventions are effective when addressing positive symptoms, treatment of negative symptoms remains an ongoing challenge. Mindfulness-based interventions (MBIs) have been...
Depression is a disorder characterized by significant and persistent depressed mood, cognitive impairment, impaired voluntary activity, working memory, and somatic symptoms. To determine the efficacy of Qi-based mindfulness therapy (QMT) in treating anxiety, depression, and sleep disturbances in individuals with mild-to-moderate depression. A self-controlled before-after trial was conducted....
Even if dissociation has various facets, it is clear that knowledge of dissociative psychosis and a dissociative schizophrenia-based viewpoint may provide new perspectives on mental disorders. Many researchers screening for comorbid symptoms of “childhood traumatic experiences” and “dissociation”, where specific characteristics are significant to the presence of psychosis and schizophrenia, may...
World Journal of PsychiatryApril 19, 2024Edison Iglesias de Oliveira Vidal, Luiz Fernando Alvarenga Ribeiro, Marco Antonio De Carvalho-Filho et al.6 citations
The high rates of depression, burnout, and increased risk of suicide among medical students, residents, and physicians in comparison with other careers signal a mental health crisis within our profession. We contend that this crisis coupled with the inadequate acquisition of interpersonal skills during medical education results from the interaction between a challenging environment and the...
With the Food and Drug Administration designation in 2017 of 3,4-methylenedioxymethamphetamine (MDMA) as a breakthrough therapy in post-traumatic stress disorder and psilocybin in treatment-resistant depression, psychedelic drugs have continued to garner the attention of researchers and clinicians for their promise of unmatched, rapid improvement in a multitude of psychiatric conditions....
Understanding neuropsychological mechanisms of mindfulness meditation (MM) has been a hot topic in recent years. This review was conducted with the goal of synthesizing empirical relationships via the genomics, circuits and networks between MM and mental disorders. We describe progress made in assessing the effects of MM on gene expression in immune cells, with particular focus on...
Sleep problems are particularly prevalent in people with depression or anxiety disorder. Although mindfulness has been suggested as an important component in alleviating insomnia, no comprehensive review and meta-analysis has been conducted to evaluate the effects of different mindfulness-based intervention (MBI) programs on sleep among people with depression or anxiety disorder. To compare the...
Depression is a common mental disorder and one of the leading causes of disability around the world. Monoaminergic antidepressants often take weeks to months to work and are not effective for all patients. This has led to a search for a better understanding of the pathogenesis of depression as well as to the development of novel antidepressants. One such novel antidepressant is ketamine, which...
Mindfulness is a psychological technique based on Eastern meditative practices that was developed in the late 1970s by Kabat-Zinn at the University of Massachusetts. Initially, there was a debate over whether it should be considered a scientific technique or labelled as part of the "new wave" practices. Today, mindfulness is omnipresent in modern societies but has suffered from merchandising...