Objective: Worldviews (WVs) are the set of beliefs that underlie the way we conceive of reality and selfhood. Buddhist meditation allegedly leads to long-lasting changes in WVs and trait-like neurophysiological and behavioral differences between novice and expert meditators support this possibility. Yet, this claim has not yet been fully tested and there is still no qualitative evidence. The...
Amidst an unfolding resurgence of psychedelic research, there is the opportunity to discuss new approaches for integrating psychedelics into both academia and society.In partnership with the newly founded Center for Psychedelic Drug Research and Education (CPDRE) at The Ohio State University, the editors of this special issue convened the Psychedemia, 2022 conference as a rigorous...
Disorders of consciousness (DoC) are a challenging and complex group of neurological conditions characterised by absent or impaired awareness. The current range of therapeutic options for DoC patients is limited, offering few non-invasive pharmacological alternatives. This situation has sprung a growing interest in the development of novel treatments, such as the proposal to study the efficacy...
Modern research on near-death experiences (NDEs), powerful spiritual experiences triggered by a close brush with death, has focused on experiences characterized by profound positive feelings, ranging from incredible peace and calmness to bliss and ecstasy. However, throughout history there have been accounts of frightening deathbed visions and terrifying journeys to a hellish realm peopled by...
Episodes of demonic or spirit possession, where individuals perceive their bodies and minds as being controlled by supernatural entities, have been the subject of extensive research across various disciplines. Despite this, the extent to which existing scientific explanations can account for these phenomena is still uncertain, especially in terms of the aspects that remain unexplained. This...
Classic psychedelics are able to profoundly alter the state of consciousness and lead to acute experiences of ego dissolution – the blurring of the distinction between representations of self and the external world. However, whether repeated use of psychedelics is associated with more prolonged and permanent modifications to the concept of self remains to be investigated. Therefore, we...
Abstract Mindfulness is said to be a connecting thread between an ancient philosophy on the one hand and a contemporary psychological practice on the other. However, some contemporary mindfulness practices have arguably become so disconnected from their roots in Buddhist ethics and wisdom principles that the fundamental essence of the practice is no longer recognisable. It appears that when...
In medieval India, the desire for “the unity of Brahman and Self” was present in the Vedānta tradition of Hinduism. Adi Śaṅkara, the master of Vedānta philosophy, proposed the six-fold sādhana: mind control, sense control, mental tranquility, endurance, potential faith, and concentration. These six-fold practices can help Vedānta followers realize unity with Brahman. In medieval Christianity,...
Background: The primary psychoactive drug in magic mushrooms, psilocybin induces profound alterations in consciousness through its action at the 5-HT2A receptor. This comprehensive review consolidates current research findings to elucidate the pharmacology, safety profile, and clinical applications of psilocybin.Areas of Uncertainty: Despite initial concerns that psilocybin could cause...
The analysis of the dialogue between the world’s philosophical cultures in recent years has been focused on the study of a special space “inter”, or “interspace”, which can be regarded as a metaphor of the “meeting place” of different cultures and approaches. Therefore, understanding the way this space is organized, its laws and principles is a precondition for the interaction of cultures and...