The innovation of Merleau-Ponty is considering the body as existence or ontology. He admitted that a mechanical psychologist could not explain our experience of the body. Thought and body are inseparable. Also, uncertainty, or as Merleau-Ponty says, bouncing, is a feature of true philosophy. Merleau-Ponty knew that he was living in a period in which two forms of absolutism overshadowed...
The Ganzfeld experiment appears as a uniform and unstructured field that may measure altered states of consciousness. The experiment uses a dim light frequency projected on translucent eye covers combined with a static audio frequency emitted through a pair of headphones. Since altered states and alpha interactions appear in Ganzfeld studies, the hypothesis here states that they may be...
Serotonergic psychedelics are known to elicit changes in conscious awareness, including perception of the environment and the self, as well as in mood, emotion and different aspects of cognition (Nichols, 2016). The effect of these compounds is complex and resists a straightforward classification that is useful for other drugs, such as “stimulants” or “sedatives”. While the effects of certain...
Please note this is a draft on which we are seeking feedback. Substantial changes and a third author are likely be added to the next version. The hard problem of consciousness asks why there is something it is like to be a conscious organism. We address this from 1st principles, by constructing a formalism that unifies lower and higher order theories of consciousness. We assume...
Split-brain subjects can consciously perceive and identify two stimuli presented simultaneously but separately in opposite hemifields. Yet, they seem to lack a conscious experience of the two stimuli together, as they cannot judge whether these are the same or different. Such breakdowns in experiential or phenomenal unity would carry important implications for philosophical reflection on the...
Along with its rapid therapeutic benefits, ketamine induces transient experience of dissociation during administration. Given the suggested association between ketamine-induced dissociation and treatment response, understanding the neural correlates of dissociation would help to elucidate its therapeutic mechanism. The posteromedial cortex (PMC) has been reported to play a vital role in the...
Understanding how a simple endogenous tryptamine could occasion profound alterations in perception and self-modeling remains a key challenge for neuroscience. We advance the Birth Echo Hypothesis (BEH) : during a narrowly defined perinatal window (≈ −2 to +24 h around delivery), a convergence of hypoxic–hypercapnic stress, maximal sensory novelty, and a poly-neuromodulatory milieu...
Background: 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), also officially known as Mebufotenin, is a naturally occurring serotonergic psychedelic alkaloid found in the venom of the Sonoran Desert toad (Incilius alvarius) and various plant species. Areas of Uncertainty: Trace levels of 5-MeO-DMT may be produced endogenously in humans, but its physiological role remains unclear. Safety profiles...
Background: N,N-dimethyltryptamine (DMT) is a naturally-occurring serotonergic psychedelic found in natural plants around the globe. As the main psychoactive component in ayahuasca, which also contains monoamine oxidase (MAO) inhibitors, DMT has been consumed as plant-based brew by indigenous peoples for centuries. Further research is required to delineate the therapeutic utility of DMT.Areas...
The present study addresses the problem of consciousness from the perspective of its phenomenological content (awareness). It examines the main contemporary theories concerning the neural correlates of consciousness, focusing on the Global Neuronal Workspace Model (GNWM) and the Higher-Order Theory (HOT). While the GNWM proposes that conscious access arises from the propagation of sensory...