Journal of Psychedelic Studies
September 10, 2026
Fernanda Kaingáng, Daiara Tukano, Adana Omágua-Kambeba et al.
Abstract The global expansion of psychedelic research, clinical translation, and policy reform has intensified debates concerning safety, equity, cultural appropriation, and Indigenous rights. A prominent contribution to these discussions is the Hopkins–Oxford Psychedelic Ethics (HOPE) Consensus Statement (Jacobs et al., 2024), which proposes a foundational ethical framework for a field...
Journal of Psychedelic Studies
September 10, 2026
Olivier Le Bon
Abstract Background The MDMA-assisted therapy landscape has been dominated by mostly holding-oriented, non-directive models. These approaches prioritize containment of the MDMA experience but leave largely unexploited the unique window of accessibility to unconscious material that MDMA creates. Objective This paper presents Active Deep Dive Therapy (ADDT), a theoretically grounded model for...
Journal of Psychedelic Studies
August 13, 2026
Kevin Feeney, Tristan Kallweit
Abstract Background and aims In the past 10 years, several publications have made the dubious assertion that Amanita muscaria is commonly used for suicidal purposes, though no primary sources are cited. Despite scientific advances in understanding A. muscaria 's pharmacology, discussion of this psychoactive mushroom in academic publications continues to be shrouded in bias and myth. The present...
Journal of Psychedelic Studies
July 21, 2026
Maria Fernanda Gebara
Abstract Background and aims In contemporary psychedelic science, integration is a central construct for describing how individuals process psychedelic experiences and translate insights into their lives (Bathje et al., 2022; Smith et al. 2024). Yet this term emerges from Western therapeutic paradigms and may not resonate with Indigenous peoples who have stewarded what has been called...
Journal of Psychedelic Studies
July 13, 2026
Nils Hörnqvist
Abstract Background Research on psilocybin's antidepressant effects has been investigated rigorously over the last 20 years. Psilocybin has been used in both major depressive disorder (MDD) and treatment resistant depression (TRD) cohort with promising results. Aims The aim of this review was to summarize the reporting practices used in psilocybin-assisted therapy (PAT) trials for MDD and TRD....
Journal of Psychedelic Studies
July 3, 2026
Henry J. Whitfield, Jan Schepers, Natasha L. Mason et al.
Abstract Despite growing interest in psychedelic-assisted psychotherapy, research investigating the psychotherapeutic components is lacking. This leaves unanswered questions regarding the psychotherapy's necessity and form. This observational study addresses this gap by measuring the outcomes of a psilocybin truffle retreat, followed by the outcomes of two psychotherapy interventions that...
Journal of Psychedelic Studies
June 26, 2026
Malin V. Uthaug, Jack G. Allocca, Martha N. Havenith et al.
Abstract Background The Pivotal Mental States (PiMS) construct posits that psychedelics and other stress-inducing practices, such as fasting and hypoxia, can evoke transformative mental states through increased serotonin receptor activation in the brain. These states are associated with enhanced cognitive flexibility, accelerated associative learning, and psychological insights that may...
Journal of Psychedelic Studies
June 12, 2026
Zuzana Postránecká, Matyáš Lucký, Viktor Mravčík et al.
Abstract The Czech Republic, like many European countries, continues to face significant challenges in treating substance use disorders (SUDs), with high relapse rates and complex comorbidities often linked to trauma and mental illness. Psychedelic-assisted psychotherapy (PAP) has re-emerged internationally as a promising therapeutic modality, although available evidence remains heterogeneous...
Journal of Psychedelic Studies
June 10, 2026
Sina Susanna Schüttler, John Nathaniel Parker, Daniel Münster
Psychedelic therapies are moving from the margins of medicine into clinical practice, bringing unresolved ethical questions to the forefront. Among them, ketamine-assisted psychotherapy (KAP) has gained the widest medical acceptance, particularly for treatment-resistant depression (TRD). In August 2025, this development reached a new stage as Norway became the first country to approve...
Journal of Psychedelic Studies
June 2, 2026
Brandon Reynante, Jack H Buchanan
Abstract Background and Aims Music has been associated with psychedelic experiences throughout human history, from ancient shamanic healing rituals to contemporary psychedelic-assisted therapy (PAT), and is considered integral for positive therapeutic outcomes. Yet optimized protocols and best practice standards for the use of music in PAT are lacking. Methods This interdisciplinary literature...
Journal of Psychedelic Studies
May 29, 2026
Alex P. Hood, Gary R Elkins
Abstract Background and Aims Psilocybin-assisted psychotherapy (PAP) is a novel, transdiagnostic treatment in which the 5-HT2A receptor agonist psilocybin is combined with psychotherapy. Studies to date have evaluated PAP's effects on depression, substance use, and end-of-life adjustment. Relatively less attention has been given to its effects on anxiety symptoms, which are highly comorbid with...
Journal of Psychedelic Studies
May 28, 2026
Lev Korchagin, Jonathan Fridman, Mario Mikulincer et al.
Abstract Background and aims This study explores the factors influencing the use of drug-testing kits as a harm reduction strategy among recreational psychedelic users in Israel. Methods Using an online survey of 422 participants, we collected data on attitudes toward testing psychedelic substances, harm reduction attitudes in the context of testing kits, accessibility to testing kits, and...
Journal of Psychedelic Studies
May 28, 2026
Rafaelle Lancelotta, Paul Nagib, Stacey B. Armstrong et al.
Abstract Background and Purpose Music plays a central role in psychedelic-assisted therapy, yet few methodologies exist to create and assess therapeutic playlists. This study aimed to illustrate a methodology for developing and evaluating a music playlist for a clinical psilocybin trial using an integrative framework grounded in theory, intentionality, and metrics. Methods A playlist was...
Journal of Psychedelic Studies
May 28, 2026
Pedro Favarón, Keith Williams, Andrée-anne Bédard
Abstract The visionary beverage known as ayawaska ( yage, oni , caapi , camaranti , etc.) among the Indigenous Nations of the Amazon has, over the past century, generated increasing academic interest and popular fascination, leading to a boom in psychedelic tourism and “neo-shamanism”. This article attempts to account for the uses of ayawaska within the contemporary cultural context of the...
Journal of Psychedelic Studies
April 15, 2026
Jean C. Vélez Rodríguez, Yanice Duquesne-Maldonado, Julián M. Hernández Torres et al.
Abstract Background and aims Psilocybin, a psychoactive compound found in fungi commonly referred to as “magic mushrooms,” is consumed for both spiritual and recreational purposes. However, psilocybin use in Puerto Rico remains understudied. This exploratory cross-sectional survey aimed to describe patterns of use, motivations for consumption, explanatory factors, personality traits, and...
Journal of Psychedelic Studies
April 15, 2026
Hannah Whitmore, Brian T Anderson, Elena Flowers et al.
Abstract Background and Aims Mental health challenges such as depression, anxiety, and existential distress are common among individuals with terminal illness. Preliminary evidence suggests that death acceptance may protect against these issues, but there is limited research on the role of psychedelic-assisted therapy in fostering death acceptance. This scoping review aims to explore the...
Journal of Psychedelic Studies
March 30, 2026
Emma Yuanqi Gu, Natalia M. Irvine, Megan Miller et al.
Abstract Introduction While the relationship between substance use disorders (SUD) and mental health conditions is well established, treatment for these co-occurring conditions is difficult to manage. Research on the potential for psychedelic treatments to address SUD and mental health conditions has recently seen a resurgence. This study aimed to explore narratives on the influence of...
Journal of Psychedelic Studies
March 30, 2026
Ismael Apud, Juan Scuro, Frank Lozano Jara et al.
Abstract Background This study presents the qualitative findings of interdisciplinary research exploring ayahuasca-induced experiences in two distinct groups in Uruguay: a neo-shamanic group rooted in the Peruvian vegetalismo tradition and a Santo Daime Church. Aims Using interpretative phenomenological analysis, the study examines similarities and differences in subjective experiences during a...
Journal of Psychedelic Studies
March 26, 2026
Aly Shah Aziz
Abstract Adolescent refractory mental health disorders are rising globally, contributing to long-term morbidity and substantial societal burden. Conventional psychotropic medications and psychotherapeutic approaches sometimes fail to provide adequate relief, necessitating an interest in novel investigational interventions. Classic psychedelic compounds—Psilocybin, Lysergic Acid Diethylamide...
Journal of Psychedelic Studies
March 9, 2026
Lajos Horváth
Abstract The aim of the paper is to complement Sartre's concept of enchanted consciousness. The first section of the paper studies the contradictions inherent in Sartre's mescaline experiment and the limits of his phenomenological analysis of hallucination. The second section argues that Benny Shanon's phenomenological cognitive psychology, which is based on the typology of ayahuasca...
Journal of Psychedelic Studies
March 9, 2026
Genís Ona, Sidsel Marie
Abstract Background and aims Ibogaine, one of the oldest psychedelic alkaloids introduced to Western society and medicine, has a largely overlooked history prior to Howard Lotsof's accidental identification of its anti-addictive properties in the 1960s. This manuscript explores some previously hidden aspects of ibogaine, with a focus on the entangled cultural, colonial, and scientific histories...
Journal of Psychedelic Studies
March 9, 2026
Noah N T Barr, Briony Larance, Matthew J. Schweickle et al.
Abstract Background and aims Increased connectedness has been proposed as one mechanism through which psychedelics might reduce death anxiety. This study examined whether changes in connectedness—across intrapersonal, interpersonal, and transpersonal domains—were associated with changes in death anxiety following a significant psychedelic experience. Methods A retrospective cross-sectional...
Journal of Psychedelic Studies
March 1, 2026
Yvan Beaussant, Candace Oglesby, Kim Roddy et al.
Abstract Background and aims Psychedelic-assisted therapies (PAT) have emerged as promising treatments for mental health conditions such as depression, anxiety, and trauma-related disorders. However, the underrepresentation of Black, Indigenous, and People of Color (BIPOC) in PAT research and clinical practice limits equitable access and the generalizability of outcomes. This study explored the...
Journal of Psychedelic Studies
February 19, 2026
Sophie Sarrassat, Suzannah Hill
Abstract Background and aims An increasing number of individuals seek psychedelics for mental illness, and when seeking psychotherapy in the aftermath, psychotherapists have an ethical duty to attempt to reduce harms and maximise benefits from these experiences. The Internal Family Systems (IFS) model of therapy is sometimes chosen as the therapeutic approach in psychedelic-assisted...
Journal of Psychedelic Studies
February 12, 2026
Matthew Hicks, Olivia Hicks, Ryan Bradley et al.
2 citations
Abstract Background and aims Despite growing popularity and increasing legal access, psychedelic therapy remains financially inaccessible to many. This study was designed to test the feasibility of conducting group psilocybin therapy in low-income adults with depression in Oregon's regulated psilocybin program. Methods An open label, uncontrolled design was used. After a medical screening...