Nature Medicine
June 3, 2025
Chloé Pronovost-Morgan, Kyle T. Greenway, Leor Roseman et al.
26 citations
Psychedelic substances exhibit complex interactions with the 'set and setting' of use, that is, the mental state of the user and the environment in which a psychedelic experience takes place. Despite these contextual variables' known importance, psychedelic research has lacked methodological rigor in reporting extra-pharmacological factors. This study aimed to generate consensus-based...
Psychiatr Res Clin Pract
February 11, 2025
Jules Evans, Marc Aixalà, Brian T Anderson et al.
18 citations
Objective: This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net. Methods: A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety. Results: The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors...
American Journal of Bioethics
2025
Neşe Devenot
3 citations
On August 9, 2024, the U.S. Food and Drug Administration (FDA) declined to approve Lykos Therapeutics’ application for MDMA-assisted therapy (MDMA-AT), in alignment with the recommendation of its i...
JAMA Network Open
June 3, 2024
Amy L. Mcguire, I Glenn Cohen, Dominic Sisti et al.
41 citations
As government agencies around the globe contemplate approval of the first psychedelic medicines, many questions remain about their ethical integration into mainstream medical practice. To identify key ethics and policy issues related to the eventual integration of psychedelic therapies into clinical practice. From June 9 to 12, 2023, 27 individuals representing the perspectives of clinicians,...
American Journal of Bioethics
May 2, 2024
Edward Jacobs, Brian D. Earp, Paul S. Appelbaum et al.
29 citations
The first Hopkins-Oxford Psychedelic Ethics (HOPE) workshop convened to discuss ethical matters relating to psychedelics in August 2023 at the University of Oxford.The organizers (BDE, DBY, EJ) aim...
Perspectives in biology and medicine
2024
Logan Neitzke-Spruill, Neşe Devenot, Dominic Sisti et al.
7 citations
ABSTRACT:Psychedelics have again become a subject of widespread interest, owing to the reinvigoration of research into their traditional uses, possible medical applications, and social implications. As evidence for psychedelics' clinical potential mounts, the field has increasingly focused on searching for mechanisms to explain the effects of psychedelics and therapeutic efficacy of...
Journal of Psychedelic Studies
December 29, 2023
Neşe Devenot, Brian A. Pace, Jason C. Slot et al.
1 citation
Amidst an unfolding resurgence of psychedelic research, there is the opportunity to discuss new approaches for integrating psychedelics into both academia and society.In partnership with the newly founded Center for Psychedelic Drug Research and Education (CPDRE) at The Ohio State University, the editors of this special issue convened the Psychedemia, 2022 conference as a rigorous...
History of Pharmacy and Pharmaceuticals
October 1, 2023
Brian P. Pace, Neşe Devenot
2 citations
The medicalization and commercialization of psychedelics stand to profit by drawing distinction and distance between their project and the contentious history of underground psychedelic use and culture. This serves at least two functions. First, by jettisoning countercultural baggage, psychedelic advocates signal a nonthreatening stance toward the power structures that enact and maintain the...
Journal of Psychedelic Studies
September 25, 2023
Neşe Devenot
9 citations
Abstract Background and Aims While many scholars have called attention to similarities between the earlier SSRI hype and the ongoing hype for psychedelic medications, the rhetoric of psychedelic hype is tinged with utopian and esoteric aspirations that have no parallel in the discourse surrounding SSRIs or other antidepressants. This utopian discourse provides insight into the ways that global...
Journal of Psychedelic Studies
September 21, 2023
James R Davies, Brian A. Pace, Neşe Devenot
29 citations
Abstract Background and Aims Advocates of psychedelic medicine have positioned psychedelics as a novel therapeutic intervention that will solve the mental health crisis by liberating individuals from their entrenched habits and limiting beliefs. Despite claims for novelty, the psychedelics industry is engaging in the same profit-oriented approaches that contributed to poor clinical outcomes...
Frontiers in Psychology
June 9, 2023
Neşe Devenot, George Erving
2 citations
OPINION article Front. Psychol., 09 June 2023Sec. Consciousness Research Volume 14 - 2023 | https://doi.org/10.3389/fpsyg.2023.1155908
JAMA Psychiatry
March 29, 2023
Sarah Mcnamee, Neşe Devenot, Meaghan Buisson
167 citations
This Viewpoint discusses serious adverse events linked to interactions between therapists and patients in trials of psychedelic-assisted therapy.
Kennedy Institute of Ethics journal
December 1, 2022
Neşe Devenot, Aidan Seale-Feldman, Elyse Smith et al.
50 citations
While the literature on psychedelic medicine emphasizes the importance of set and setting alongside the quality of subjective drug effects for therapeutic efficacy, few scholars have explored the therapeutic frameworks that are used alongside psychedelics in the lab or in the clinic. Based on a narrative analysis of the treatment manual and post-session experience reports from a pilot study of...
Anthropology of Consciousness
August 22, 2022
Neşe Devenot, Trey Conner, Richard Doyle
45 citations
Psychedelic or ecodelic medicines (e.g., psilocybin, ayahuasca, iboga) for the care and treatment of addiction, post‐traumatic stress disorder, cancer, cluster headaches, anxiety, and depression have surged to the forefront of discussions about mental health in the US, leading to the emergence of well‐capitalized biotech companies offering multimillion‐dollar IPOs. Venture capital website...
Frontiers in Psychology
December 10, 2021
Brian A. Pace, Neşe Devenot
65 citations
Recent media advocacy for the nascent psychedelic medicine industry has emphasized the potential for psychedelics to improve society, pointing to research studies that have linked psychedelics to increased environmental concern and liberal politics. However, research supporting the hypothesis that psychedelics induce a shift in political beliefs must address the many historical and contemporary...
International Journal of Cultural Studies
June 9, 2021
Alex K. Gearin, Neşe Devenot
40 citations
Emerging from a diverse and long history of shamanic and religious cultural practices, psychedelic substances are increasingly being foregrounded as medicines by an assemblage of scientific research groups, media institutions, government drug authorities, and patient and consumer populations. Considering scientific studies and recent popular media associated with the medicalization of...
European Romantic Review
January 2, 2019
Neşe Devenot
Contributing to recent scholarly interest in the cognitive and perceptual ideas that informed Romantic interest in transcendence, this paper argues for a common self-experimental method underlying Humphry Davy’s medical experiments with nitrous oxide and the composition of lyric poetry by William Wordsworth and Samuel Taylor Coleridge. Romantic poets and scientists adopted the formal method of...
Journal of Humanistic Psychology
June 14, 2017
Thomas Cody Swift, Alexander Belser, Gabrielle Agin-Liebes et al.
187 citations
Recent randomized controlled trials of psilocybin-assisted psychotherapy for patients with cancer suggest that this treatment results in large-magnitude reductions in anxiety and depression as well as improvements in attitudes toward disease progression and death, quality of life, and spirituality. To better understand these findings, we sought to identify psychological mechanisms of action...
Journal of Humanistic Psychology
April 28, 2017
Alexander Belser, Gabrielle Agin-Liebes, Thomas Cody Swift et al.
305 citations
The psychological mechanisms of action involved in psilocybin-assisted psychotherapy are not yet well understood. Despite a resurgence of quantitative research regarding psilocybin, the current study is the first qualitative study of participant experiences in psilocybin-assisted psychotherapy. Semistructured interviews were carried out with 13 adult participants aged 22 to 69 years ( M = 50...