bioRxiv (Cold Spring Harbor Laboratory)
December 11, 2025
Caroline L. Alves, Fernanda Palhano-Fontes, Thaise G. L. de O. Toutain et al.
Abstract Ayahuasca profoundly alters conscious experience, yet robust, time-resolved EEG markers of its network-level effects remain limited. We combined machine learning with complex-network analysis to quantify how functional connectivity reorganizes across time and hemispheres in resting-state EEG from a randomized, double-blind, placebo-controlled trial including three 5-min sessions:...
Journal of Physics: Complexity
January 22, 2024
Caroline L. Alves, Manuel Ciba, Thaise G. L. de O. Toutain et al.
5 citations
There is a growing interest in the medical use of psychedelic substances, as preliminary studies using them for psychiatric disorders have shown positive results. In particular, one of these substances is N, N-dimethyltryptamine (DMT), an agonist serotonergic psychedelic that can induce profound alterations in the state of consciousness. In this work, we use an exploratory tool to reveal...
May 5, 2023
Caroline L. Alves
Data mining and knowledge discovery is a research area with applications in various fields, such as medicine. Data mining methods have proven to be very effective in making automated diagnoses and help medical teams in decision making. In addition to using data mining, medical data can be represented by complex networks. In the case of the brain, for example, brain regions can be represented as...
PLoS One
December 16, 2022
Caroline L. Alves, Rubens Gisbert Cury, Kirstin Roster et al.
13 citations
Ayahuasca is a blend of Amazonian plants that has been used for traditional medicine by the inhabitants of this region for hundreds of years. Furthermore, this plant has been demonstrated to be a viable therapy for a variety of neurological and mental diseases. EEG experiments have found specific brain regions that changed significantly due to ayahuasca. Here, we used an EEG dataset to...
medRxiv
June 16, 2022
Caroline L. Alves, Thaise G. L. de O. Toutain, Joel Augusto Moura Porto et al.
preprint
There is a growing interest in the medical use of psychedelic substances as preliminary studies using them for psychiatric disorders have shown positive results. In particularly, one of these substances is N,N-dimethyltryptamine (DMT) an agonist serotonergic psychedelic that can induce profound alterations in state of consciousness. In this work, we propose a computational method based on...