The psychedelic brew ayahuasca is increasingly being investigated for its therapeutic potential. Animal models are essential to investigate the pharmacological effects of ayahuasca since they can control important factors influencing it, such as the set and setting. Review and summarise data available on ayahuasca research using animal models. We systematically searched five databases (PubMed,...
Traditional therapies, resorting to the use of plants, have acquired a great demand over the years, both for economic reasons and the preference for natural treatments. Some studies suggest that ayahuasca may have beneficial properties in treating some physical and psychological imbalances. Thus, we carried out a systematic review of studies published up to December 2022, where these themes...
Emerging insights from metabolomic-based studies of major depression disorder (MDD) are mainly related to biochemical processes such as energy or oxidative stress, in addition to neurotransmission linked to specific metabolite intermediates. Hub metabolites represent nodes in the biochemical network playing a critical role in integrating the information flow in cells between metabolism and...
El movimiento conocido como Inner Mastery (anteriormente, Ayahuasca Internacional), fundado por el argentino Alberto Varela y con sede central en España, es uno de los grupos neochamánicos más destacados en el panorama actual. En marzo de 2020, cuando se impuso el confinamiento domiciliario en muchos países a causa de la pandemia, Varela aseguró que él era el creador del COVID-19, y siguió...
Ayahuasca is an Amazonian psychoactive plant medicine being explored for its potential therapeutic uses in Western contexts. Preliminary studies link ayahuasca use with improvements across a range of mental health indicators, but studies have not yet explored qualitative aspects of the post-treatment process known in the psychedelic literature as “integration”. This includes how participants...
Abstract On February 2023, the Drug Enforcement Administration (DEA) released a document to the legal team representing the Church of the Eagle and the Condor (“CEC”). This disclosure came two years after the church, in conjunction with Chacruna Institute, submitted two FOIA requests to the DEA and the Department of Justice requesting all records pertaining to ayahuasca. This report, titled...
The present study examined the safety and efficacy of the ceremonial use of ayahuasca in relation to reports of heightened life event reexperiencing under psychedelics. The study examined (1) the prevalence of specific types of adverse life event reexperiencing, (2) characteristics predictive of reexperiencing, (3) the psychological character of reexperiencing, and (4) the impact of...
Ayahuasca is a psychedelic brew that has been the focus of an increasing number of investigations for its potential therapeutic effects. In addition to psychiatric improvements, qualitative studies and anecdotal reports suggest that ayahuasca use may influence gratitude and relationships with nature. Yet, to date, these specific changes have been understudied. Here, participants (N = 54)...
Abstract Classic psychedelics, lysergic acid diethylamide, psilocybin, mescaline and N,N-dimethyltryptamine, are potent psychoactive substances that have been studied for their physiological and psychological effects. However, our understanding of the potential interactions and outcomes of using these substances are used in combination with other psychoactive drugs is limited. This systematic...
There is increasing interest in exploring the therapeutic potential of psychedelics in treatment-resistant depression (TRD). Classic psychedelics (such as psilocybin, LSD, ayahuasca/DMT), and atypical psychedelics (such as ketamine) have been studied in TRD. The evidence for the classic psychedelics TRD is limited at the present time; early studies however show promising results. There is also...
Recursos alternativos à medicina estão em ascensão quando da procura por alternativas que auxiliem na superação das problemáticas relacionadas ao estresse, ansiedade, problemas comportamentais e psicológicos, levando o indivíduo a sensação do bem-estar e atuando tais sintomatologias. A Ayahuasca é uma bebida tradicionalmente usada em cerimônias indígenas da região amazônica, e tem sido...
With the Food and Drug Administration designation in 2017 of 3,4-methylenedioxymethamphetamine (MDMA) as a breakthrough therapy in post-traumatic stress disorder and psilocybin in treatment-resistant depression, psychedelic drugs have continued to garner the attention of researchers and clinicians for their promise of unmatched, rapid improvement in a multitude of psychiatric conditions....
A religião sempre teve uma relação inextricável com a música. O presente artigo é um estudo a respeito da importância que a musicalidade teve na origem, na memorização e na transferência do corpus religioso em tradições milenares; e ainda, sobre como ela continua sendo relevante atualmente em religiões recém-criadas de tradição ayahuasqueira como o Santo Daime e a União do Vegetal. A...
Psychedelic drugs are currently being investigated for their potential to facilitate a variety of long-lasting psychological changes. One area of psychological functioning that has yet to be systematically investigated in psychedelic research regards aesthetic experiences. This is surprising given the notable acute changes in perception induced by the drugs as well as the wealth of anecdotal...
The purpose of this review article is to give a summary of the literature on the use of psychedelic drugs, such as psilocybin, LSD, ayahuasca, and MDMA, in the treatment of various mental health conditions, such as depression, anxiety, PTSD, and substance use disorders. This review's main goal is to highlight recent human studies on the use of particular psychedelic drugs, like psilocybin, LSD,...
Ayahuasca, the main Amazonian entheogen, increases its presence within Brazilian society with the foundation of Santo Daime religion in the state of Acre in 1930. Along the following decades, turned into a syncretic religion, the pre-Columbian brew leaves the jungle and heads to the cities. The dissemination of ayahuasca throughout Brazil is an expression of entheogenic mobility, a phenomenon...
A Ayahuasca é uma poderosa bebida psicoativa que tem sido usada há séculos por comunidades indígenas na América do Sul para fins espirituais e medicinais. A bebida é feita fervendo o cipó da ayahuasca (Banisteriopsis caapi) e as folhas da planta chacrona (Psychotria viridis), criando uma potente experiência psicadélica que pode durar várias horas. Nos últimos anos, tem havido um interesse...
TomoApril 14, 2023Andréa Depieri de Albuquerque Reginato
A partir do debate da questão do uso da ayahuasca para fins religiosos, este artigo apresenta e discute os diferentes padrões de normatização adotados nos últimos 20 anos no Brasil, com destaque para o debate em torno da criminalização. A sociedade pós-industrial e a condição pós-moderna aparecem como pano de fundo frente aos dilemas que a questão suscita.