This article examines how religious experience is articulated through genre in the poetry of the seventeenth-century Ottoman Mawlawī shaykh Neshāṭī (d. 1674), focusing on the striking contrast between his ghazals and non-ghazal compositions. While Neshāṭī’s qaṣīdas, mathnawīs and other formal genres employ an explicit and direct religious language—addressing God, the Prophet, sacred figures,...
Abstract Objectives Deconstructive meditative practices (DMPs) aim to transform the perception of the self by fostering an understanding of its constructed and impermanent nature through self-inquiry. This systematic review evaluated the effectiveness of DMPs in improving mental health and psychological well-being among adults. Method Following PRISMA guidelines, a comprehensive search was...
PsychopathologyMarch 27, 2026Xiaoran Ding, Yaping Wu, Juan Yang et al.1 citation
Ketamine has emerged as a promising rapid-acting antidepressant with distinct advantages for the treatment of treatment-resistant depression (TRD). Its therapeutic effects are mediated through multi-target modulation of the glutamatergic system. Unlike conventional antidepressants, ketamine exerts a markedly faster onset of action; however, its long-term safety profile and potential risk of...
Comorbidity between post-traumatic stress disorder (PTSD) and alcohol use is common and mutually-reinforcing, yet there are no pharmacological strategies that specifically target trauma-linked escalation of alcohol intake. We evaluated whether 3,4-methylenedioxymethamphetamine (MDMA), given in a therapy-adjunctive fashion (30 min before fear extinction), could facilitate extinction of...
N,N-dimethyltryptamine (DMT) is a serotonergic psychedelic that produces short-lived peak effects when administered intravenously as a bolus dose. Initial trials suggested therapeutic effects of DMT in depressive disorders. However, systematic data on dose-dependent pharmacokinetics and acute effects of intravenous bolus DMT administration are currently lacking. We used a double-blind,...
Abstract Adolescent refractory mental health disorders are rising globally, contributing to long-term morbidity and substantial societal burden. Conventional psychotropic medications and psychotherapeutic approaches sometimes fail to provide adequate relief, necessitating an interest in novel investigational interventions. Classic psychedelic compounds—Psilocybin, Lysergic Acid Diethylamide...
Brain SciencesMarch 26, 2026Piotr Skalski, Katarzyna Pękacka-falkowska, Agnieszka Pluto-Prądzyńska et al.
Background/Objectives: Psilocybin has re-emerged as a promising intervention for neuropsychiatric disorders including major depressive disorder, treatment-resistant depression, anxiety associated with life-threatening illness, obsessive compulsive disorder, and substance use disorders. However, conventional randomized controlled trials (RCTs)-the current gold standard in evidence-based...
Masking priming research into unconscious perception has a long history of ambiguous findings and controversies. Tsikandilakis and colleagues (2025) offer several commendable methodology recommendations that might resolve ambiguities and lead to compelling findings. However, better methodology might be insufficient to fully address the weaknesses of the null awareness paradigm. The expected...
The review article of the book by James Braid, "Neuropnology or the rationale of nervous sleep, considered in connection with animal magnetism," is intended to draw attention to the treatise of the outstanding surgeon and hypnologist of the 19th century, who was the first to color the physiological interpretation of the previously mystical method of hypnosis under the monopoly of Mesmerists....