Abstract The turn of the century brought a resurgence of interest in psychedelics as a treatment for addiction and other psychiatric conditions, accompanied by extensive positive media attention and private equity investment. Government regulatory bodies in Australia, Israel, Canada and the United States now permit use of psychedelics for medical purposes. In the United States, citizen action...
This article aims to present "iboga," also known as "sacred wood," as an endogenous knowledge used traditionally in the spiritual and medicinal rituals of the people of Gabon during initiation ceremonies such as bwiti, mumbwiri, and many other rites. This plant, considered a natural, cultural, and national heritage, allows for transcendence between physical and invisible worlds through its...
PsychiatriaJune 5, 2024Anna Stankiewicz, Jan Szewczyk, Julia Truszkowska et al.1 citation
Drug therapies for many psychiatric conditions do not meet patients’ expectations. New agents are being sought to treat depression and anxiety disorders, among others. Scientific interest in psychoactive substances has increased over the past few decades. Recent studies provide evidence that psychedelics may find use in the treatment of a range of mental disorders. This paper describes new...
Substituted phenethylamines including 2C (2,5-dimethoxyphenethylamines) and NBOMe (N-(2-methoxybenzyl)phenethylamines) drugs are potent psychoactive substances with little to no knowledge available on their toxicity. In the present in vitro study, we explored the mechanisms underlying the neurotoxicity of six substituted phenethylamines: 2C-T-2, 2C-T-4, 2C-T-7 and their corresponding NBOMes....
Background Numerous clinical trials have supported psychedelic-assisted therapy (PAT) as a treatment for psychiatric disorders such as depression, anxiety, post-traumatic stress, and substance use. While empirical evidence indicates PAT’s benefits, the perspectives of mental health practitioners on this topic remain unclear.Methods This quantitative study attempted to capture psychoanalyst...
Brain SciencesJune 3, 2024Gianluca Ficca, Oreste De Rosa, Davide Giangrande et al.1 citation
Positive symptoms of schizophrenia have been proposed to be an intrusion of dreaming in wakefulness; conversely, psychotic patients' abnormal cognitive and behavioral features could overflow into sleep, so that their dreams would differ from those of healthy people. Here we assess this hypothesis by comparing dream features of 46 patients affected by schizophrenic spectrum disorders to those of...
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR), recently identified internet gaming disorder (IGD) as a condition warranting more research, and few empirically validated treatments exist. Mindfulness meditation (MM) has multiple health benefits; however, its efficacy in treating IGD and potential neural mechanisms underlying MM treatment of...
PeerJJune 3, 2024Mengyang Xu, Haifei Shi, Andor J. Kiss et al.5 citations
Background Psilocybin and related tryptamines have come into the spotlight in recent years as potential therapeutics for depression. Research on the mechanisms of these effects has historically focused on the direct effects of these drugs on neural processes. However, in addition to such neural effects, alterations in peripheral physiology may also contribute to their therapeutic effects. In...
Ayahuasca, un té utilizado inicialmente por pueblos amerindios, con fines medicinales, religiosos y sacramentales, y luego se difundió en muchas partes del mundo en contextos urbanos, que, además de su uso religioso y espiritual, también el uso recreativo. El té de ayahuasca contiene un perfil químico bien característico de compuestos alcaloides psicoactivos que son N, N-dimetiltriptamina (DMT)...
This study was conducted to examine the effect of the online Mindfulness-Based Stress Reduction (MBSR) programme applied to pregnant women on their prenatal comfort and foetal anxiety levels. This randomised controlled study was conducted between July and October 2022, with 89 pregnant women registered in a Family Health Centre of Adiyaman, located in the Southeastern Anatolia region of Turkey....