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Adam Safron

26 papers in the library · 268 citations · publishing 2014-2026

Papers

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Integrated World Modeling Theory (IWMT) and the Human Consciousness Hypothesis (HCH)

Proceedings of the AAAI Symposium Series May 18, 2026 Adam Safron, Victoria Klimaj, Zahra Sheikhbahaee

Here, we explore points of convergence between the Human Consciousness Hypothesis (HCH) and Integrated World Modeling Theory (IWMT). HCH posits that consciousness is defined by three fundamental principles: Genesis (conscious functions constituting an early-stage learning algorithm), Coherence (maximization of representational consistency), and Second-Order Perception (synchronous...

DOI: 10.1609/aaaiss.v8i1.42564 (opens in new tab) Artificial consciousness Embodied cognition Cognitive architecture Perception +8

Computational spirits: a neuroscientific account of psychedelic entity encounters.

Neuroscience of Consciousness 2026 Jonas Mago, George Deane, Lars Sandved-Smith et al.

Under the influence of psychedelics, people often report encountering "entities" who seem to have their own autonomous agency. Depending on the cultural milieu, these entities are reported to take a variety of forms, including spirits, elves, ancestors, or fragments of the self. Encounters with such beings hold a central place in many traditions of psychedelic practice around the world. And...

On the varieties of conscious experiences: Altered Beliefs Under Psychedelics (ALBUS).

Neuroscience of Consciousness 2025 Adam Safron, Arthur Juliani, Nicco Reggente et al. 44 citations

How is it that psychedelics so profoundly impact brain and mind? According to the model of "Relaxed Beliefs Under Psychedelics" (REBUS), 5-HT2a agonism is thought to help relax prior expectations, thus making room for new perspectives and patterns. Here, we introduce an alternative (but largely compatible) perspective, proposing that REBUS effects may primarily correspond to a particular (but...

DOI: 10.1093/nc/niae038 (opens in new tab) Full text (opens in new tab) Neuroplasticity Consciousness-states Default-mode-network Belief-systems +4

How do inner screens enable imaginative experience? Applying the free-energy principle directly to the study of conscious experience.

Neuroscience of Consciousness 2025 Chris Fields, Mahault Albarracin, Karl Friston et al. 6 citations

This paper examines the constraints that the free-energy principle (FEP) places on possible model of consciousness, particularly models of attentional control and imaginative experiences, including episodic memory and planning. We first rehearse the classical and quantum formulations of the FEP, focusing on their application to multi-component systems, in which only some components interact...

DOI: 10.1093/nc/niaf009 (opens in new tab) Full text (opens in new tab) Depression Aphantasia Cognitive architecture Inner speech +13

Disintegrating and reintegrating the self—(in)flexible self-models in depersonalization and psychedelic experiences

Philosophical Perspectives on Psychedelic Psychiatry September 13, 2024 Anna Ciaunica, Adam Safron

Abstract This chapter examines the feeling of ‘losing’ the sense of familiarity with one’s self and body in depersonalization and psychedelic experiences through an ‘active inference’ lens. It is suggested that psychedelic-induced experiences may involve a stance with radically altered prior expectations, providing opportunities for flexibly modulating self- and world models. Specifically,...

A dual-receptor model of serotonergic psychedelics

bioRxiv (Cold Spring Harbor Laboratory) April 15, 2024 Arthur Juliani, Veronica Chelu, Laura Graesser et al. 4 citations preprint

Abstract Serotonergic psychedelics have been identified as promising next-generation therapeutic agents in the treatment of mood and anxiety disorders. While their efficacy has been increasingly validated, the mechanism by which they exert a therapeutic effect is still debated. A popular theoretical account is that excessive 5-HT2a agonism disrupts cortical dynamics, relaxing the precision of...

Deep CANALs: a deep learning approach to refining the canalization theory of psychopathology

Neuroscience of Consciousness 2024 Arthur Juliani, Adam Safron, Ryota Kanai 9 citations

Abstract Psychedelic therapy has seen a resurgence of interest in the last decade, with promising clinical outcomes for the treatment of a variety of psychopathologies. In response to this success, several theoretical models have been proposed to account for the positive therapeutic effects of psychedelics. One of the more prominent models is “RElaxed Beliefs Under pSychedelics,” which proposes...

DOI: 10.1093/nc/niae005 (opens in new tab) Full text (opens in new tab) Psychopathology Variety cybernetics Cognitive psychology Representation politics +6

Editorial: Bio A.I. - from embodied cognition to enactive robotics.

Frontiers in Neurorobotics November 14, 2023 Adam Safron, Inês Hipólito, Andy Clark 2 citations

If we consider the kinds of intelligence generated by brain-body-environment systems, then such emergent minds may be vaster still in terms of their complex combinatorics, with the pinnacle of expressive power potentially being found in language with its “infinite use of finite means”. The field of artificial intelligence and machine learning (AI/ML) seeks to reproduce the powers of biological...

DOI: 10.3389/fnbot.2023.1301993 (opens in new tab) Full text (opens in new tab) Robotics Dynamical systems Embodiment Active learning +4

Steps towards a minimal unifying model of consciousness: An integration of models of consciousness based on the free energy principle

July 6, 2023 Maxwell J D Ramstead, Mahault Albarracin, Alex Kiefer et al. 4 citations preprint

This paper aims to assess whether the recently proposed "inner screen model" of consciousness that follows from the free-energy principle (FEP) can be regarded as a minimal unifying model (MUM) of consciousness, thereby providing a common foundational model for consciousness studies, and integrating approaches to consciousness based on the FEP. We first present the inner screen model, which...

The inner screen model of consciousness: applying the free energy principle directly to the study of conscious experience

April 20, 2023 Maxwell J D Ramstead, Mahault Albarracin, Alex Kiefer et al. 15 citations preprint

This paper presents a model of consciousness that follows directly from the free- energy principle (FEP). We first rehearse the classical and quantum formulations of the FEP. In particular, we consider the “inner screen hypothesis” that follows from the quantum information theoretic version of the FEP. We then review applications of the FEP to the known sparse (nested and hierarchical)...

As without, so within: how the brain's temporo-spatial alignment to the environment shapes consciousness

Interface Focus April 14, 2023 Georg Northoff, Philipp Klar, Magnus Bein et al. 30 citations

Consciousness is constituted by a structure that includes contents as foreground and the environment as background. This structural relation between the experiential foreground and background presupposes a relationship between the brain and the environment, often neglected in theories of consciousness. The temporo-spatial theory of consciousness addresses the brain-environment relation by a...

DOI: 10.1098/rsfs.2022.0076 (opens in new tab) Full text (opens in new tab) Consciousness Entrainment biomusicology Layer electronics Cognitive psychology +2

Cognitive Science Below the Neck: Toward an Integrative Account of Consciousness in the Body

Cognitive Sciences March 1, 2023 Leonardo Christov-Moore, Alex Jinich-Diamant, Adam Safron et al.

Our culture and its scientific endeavor direly need a holistic characterization of mind and body. Many phenomena attest to the profound effects of beliefs on bodily function (e.g., open-label placebo's effects on chronic pain) and interoceptive systems' role in mental processes (e.g., the emerging role of gut microbiomes in the mood). We need a mechanistic, integrative framework to account for...

Integrated world modeling theory expanded: Implications for the future of consciousness.

Frontiers in Computational Neuroscience November 24, 2022 Adam Safron 32 citations

Integrated world modeling theory (IWMT) is a synthetic theory of consciousness that uses the free energy principle and active inference (FEP-AI) framework to combine insights from integrated information theory (IIT) and global neuronal workspace theory (GNWT). Here, I first review philosophical principles and neural systems contributing to IWMT's integrative perspective. I then go on to...

Classic psychedelics: past uses, present trends, future possibilities

September 8, 2022 Adam Safron, Matthew Johnson 5 citations preprint

Here we consider psychedelics with respect to their mechanisms of action, use, and implications for our understandings of brain and mind. This review is somewhat nontraditional in its scope, with discussions of both basic facts as well as theoretical speculations. We chose this approach given the unique historical context we find ourselves in at present. While we have decades of investigations...

Disintegrating and Reintegrating the Self – (In)Flexible Self-Models in Depersonalisation and Psychedelic Experiences

March 13, 2022 Anna Ciaunica, Adam Safron 8 citations preprint

Across times and cultures, humans constantly and intentionally tried to ‘lose’ or to ‘escape’ their familiar, ordinary self, to ‘self-detach’ and to radically change the ways of perceiving oneself and the world. In this paper we explore the contrast between the feeling of ‘losing’ the sense of familiarity with one’s self and body in Depersonalisation experiences (DP) and psychedelics (with some...

DOI: 10.31234/osf.io/mah78 (opens in new tab) Full text (opens in new tab) Feeling Self Perception Cognitive psychology +3

Integrated World Modeling Theory (IWMT) Expanded: Implications for Theories of Consciousness and Artificial Intelligence

June 21, 2021 Adam Safron preprint

Integrated World Modeling Theory (IWMT) is a synthetic theory of consciousness that uses the Free Energy Principle and Active Inference (FEP-AI) framework to combine insights from Integrated Information Theory (IIT) and Global Neuronal Workspace Theory (GNWT). Here, I first review philosophical principles and neural systems contributing to IWMT’s integrative perspective. I then go on to...

The Radically Embodied Conscious Cybernetic Bayesian Brain: From Free Energy to Free Will and Back Again.

Entropy (Basel, Switzerland) June 20, 2021 Adam Safron 53 citations

Drawing from both enactivist and cognitivist perspectives on mind, I propose that explaining teleological phenomena may require reappraising both "Cartesian theaters" and mental homunculi in terms of embodied self-models (ESMs), understood as body maps with agentic properties, functioning as predictive-memory systems and cybernetic controllers. Quasi-homuncular ESMs are suggested to constitute...

DOI: 10.3390/e23060783 (opens in new tab) Full text (opens in new tab) Bayesian brain Free energy principle Active inference Agency +15

Back to square one: the bodily roots of conscious experiences in early life.

Neuroscience of Consciousness 2021 Anna Ciaunica, Adam Safron, Jonathan Delafield-Butt

Most theoretical and empirical discussions about the nature of consciousness are typically couched in a way that endorses a tacit adult-centric and vision-based perspective. This paper defends the idea that consciousness science may be put on a fruitful track for its next phase by examining the nature of subjective experiences through a bottom-up developmental lens. We draw attention to the...

DOI: 10.1093/nc/niab037 (opens in new tab) Full text (opens in new tab) Consciousness Embodiment In utero perception Predictive processing +1

Integrated World Modeling Theory (IWMT) Implemented: Towards Reverse Engineering Consciousness with the Free Energy Principle and Active Inference

International Workshop on Affective Interactions August 28, 2020 Adam Safron preprint

Integrated World Modeling Theory (IWMT) is a synthetic model that attempts to unify theories of consciousness within the Free Energy Principle and Active Inference framework, with particular emphasis on Integrated Information Theory (IIT) and Global Neuronal Workspace Theory (GNWT). IWMT further suggests predictive processing in sensory hierarchies may be well-modeled as (folded, sparse,...

An Integrated World Modeling Theory (IWMT) of Consciousness: Combining Integrated Information and Global Neuronal Workspace Theories With the Free Energy Principle and Active Inference Framework; Toward Solving the Hard Problem and Characterizing Agentic Causation.

Frontiers in Artificial Intelligence 2020 Adam Safron

The Free Energy Principle and Active Inference Framework (FEP-AI) begins with the understanding that persisting systems must regulate environmental exchanges and prevent entropic accumulation. In FEP-AI, minds and brains are predictive controllers for autonomous systems, where action-driven perception is realized as probabilistic inference. Integrated Information Theory (IIT) begins with...

DOI: 10.3389/frai.2020.00030 (opens in new tab) Full text (opens in new tab) Active inference Autoencoder Autonomy Consciousness +4

Integrated World Modeling Theory (IWMT) Revisited

PsyArXiv December 15, 2019 Adam Safron preprint

Here, I provide clarifications and discuss further issues relating to Safron (2020), “An Integrated World Modeling Theory (IWMT) of consciousness: Combining Integrated Information and Global Workspace Theories with the Free Energy Principle and Active Inference Framework; towards solving the Hard problem and characterizing agentic causation.” As a synthesis of major theories of complex systems...

What is orgasm? A model of sexual trance and climax via rhythmic entrainment.

Socioaffective neuroscience & psychology 2016 Adam Safron 56 citations

Orgasm is one of the most intense pleasures attainable to an organism, yet its underlying mechanisms remain poorly understood. On the basis of existing literatures, this article introduces a novel mechanistic model of sexual stimulation and orgasm. In doing so, it characterizes the neurophenomenology of sexual trance and climax, describes parallels in dynamics between orgasms and seizures,...

DOI: 10.3402/snp.v6.31763 (opens in new tab) Full text (opens in new tab) Evolution Mate choice Neural entrainment Orgasm +3

Benefits of mindfulness training for patients with progressive cognitive decline and their caregivers.

American journal of Alzheimer's disease and other dementias August 25, 2014 Ken A Paller, Jessica D Creery, Susan M Florczak et al.

New strategies are needed to help people cope with the repercussions of neurodegenerative disorders such as Alzheimer's disease. Patients and caregivers face different challenges, but here we investigated an intervention tailored for this combined population. The program focused on training skills such as attending to the present moment nonjudgmentally, which may help reduce maladaptive...

World Modeling, Integrated Information, and the Physical Substrates of Consciousness; Hidden Sources of the Stream of Experience?

Adam Safron preprint

In this brief commentary on The Hidden Spring: A Journey to the Source of Consciousness, I describe ways in which Mark Solms’ account of the origins of subjective experience relates to Integrated World Modeling Theory (IWMT). IWMT is a synthetic theory that brings together different perspectives, with the ultimate goal of solving the enduring problems of consciousness, including the Hard...

On the degrees of freedom worth having: psychedelics as means of understanding and expanding free will

Adam Safron preprint

What do we mean when we talk of “free will?” What are the “varieties of free will worth having” (Dennett, 2003), and to what extent can we be said to possess such capabilities? While preferred definitions may vary across individuals and situations, we may perhaps find broad agreement that free will indicates a capacity for conscious intentions to meaningfully cause actions, which could be...