Clinical Neurophysiology
November 27, 2019
Olivia Gosseries, Matteo Fecchio, Audrey Wolff et al.
https://doi.org/10.1016/j.clinph.2019.11.011 1388-2457/ 2019 The Authors. Published by Elsevier B.V. on behalf of In This is an open access article under the CC BY-NC-ND license (http://creativ Cognitive trance is defined as a volitional, purposeful and selfinduced modified state of consciousness (inherited from shamanic traditional practice), characterized by lucid but narrowed awareness of...
Scientific Reports
October 1, 2019
Charlotte Martial, Armand Mensen, Vanessa Charland-Verville et al.
36 citations
The neurobiological basis of near-death experiences (NDEs) is unknown, but a few studies attempted to investigate it by reproducing in laboratory settings phenomenological experiences that seem to closely resemble NDEs. So far, no study has induced NDE-like features via hypnotic modulation while simultaneously measuring changes in brain activity using high-density EEG. Five volunteers who...
Frontiers in Systems Neuroscience
August 14, 2019
Vincent Bonhomme, Cécile Staquet, Javier Montupil et al.
109 citations
General anesthesia reversibly alters consciousness, without shutting down the brain globally. Depending on the anesthetic agent and dose, it may produce different consciousness states including a complete absence of subjective experience (unconsciousness), a conscious experience without perception of the environment (disconnected consciousness, like during dreaming), or episodes of oriented...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
July 1, 2019
Minji Lee, Benjamin Baird, Olivia Gosseries et al.
4 citations
The aim of the study was to investigate differences in cortical networks based on the state of consciousness. Five subjects performed a serial-awakening paradigm with electroencephalography (EEG) recordings. We considered four states of consciousness: (1) non-rapid eye movement (NREM) sleep with no conscious experience, (2) NREM sleep with conscious experience, (3) rapid eye movement (REM)...
Scientific Reports
March 26, 2019
Minji Lee, Benjamin Baird, Olivia Gosseries et al.
98 citations
The neuronal connectivity patterns that differentiate consciousness from unconsciousness remain unclear. Previous studies have demonstrated that effective connectivity, as assessed by transcranial magnetic stimulation combined with electroencephalography (TMS-EEG), breaks down during the loss of consciousness. This study investigated changes in EEG connectivity associated with consciousness...
Neuroimage
January 11, 2019
Michele A. Colombo, Martino Napolitani, Melanie Boly et al.
359 citations
Despite the absence of responsiveness during anesthesia, conscious experience may persist. However, reliable, easily acquirable and interpretable neurophysiological markers of the presence of consciousness in unresponsive states are still missing. A promising marker is based on the decay-rate of the power spectral density (PSD) of the resting EEG. We acquired resting electroencephalogram (EEG)...
Scientific Reports
December 6, 2018
Benjamin Baird, Anna Castelnovo, Olivia Gosseries et al.
74 citations
Humans typically lack awareness that they are dreaming while dreaming. However, at times a remarkable exception occurs and reflective consciousness can be regained while dreaming, referred to as lucid dreaming. While most individuals experience lucid dreams rarely there is substantial variance in lucid dream frequency. The neurobiological basis of lucid dreaming is unknown, but evidence points...
Scientific Reports
November 5, 2018
Matthieu Darracq, Chadd M. Funk, Daniel Polyakov et al.
49 citations
Sleep and anesthesia entail alterations in conscious experience. Conscious experience may be absent (unconsciousness) or take the form of dreaming, a state in which sensory stimuli are not incorporated into conscious experience (disconnected consciousness). Recent work has identified features of cortical activity that distinguish conscious from unconscious states; however, less is known about...
Brain Stimulation
November 1, 2018
Olivier Bodart, Matteo Fecchio, Marcello Massimini et al.
Meditation can be conceptualized as a family of complex emotional and attentional regulatory training regimes developed for various ends, including the cultivation of well-being and emotional balance. Previous studies have demonstrated that meditation may have positive effects on self-awareness, emotion regulation, attention processes, and also structural neuroplasticity [1]. However, the...
Frontiers in Neurology
August 28, 2018
Audrey Vanhaudenhuyse, Vanessa Charland-Verville, Aurore Thibaut et al.
Despite recent advances in our understanding of consciousness disorders, accurate diagnosis of severely brain-damaged patients is still a major clinical challenge. We here present the case of a patient who was considered in an unresponsive wakefulness syndrome/vegetative state for 20 years. Repeated standardized behavioral examinations combined to neuroimaging assessments allowed us to show...
Frontiers in Neuroscience
2018
Rajanikant Panda, Olivia Gosseries, Audrey Vanhaudenhuyse et al.
2 citations
Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
Journal of Neuroscience
February 8, 2017
Jason Samaha, Olivia Gosseries, Bradley R. Postle
131 citations
Transcranial magnetic stimulation (TMS) of human occipital and posterior parietal cortex can give rise to visual sensations called phosphenes. We used near-threshold TMS with concurrent EEG recordings to measure how oscillatory brain dynamics covary, on single trials, with the perception of phosphenes after occipital and parietal TMS. Prestimulus power and phase, predominantly in the alpha band...
Annals of Neurology
September 22, 2016
Silvia Casarotto, Angela Comanducci, Mario Rosanova et al.
504 citations
OBJECTIVE: Validating objective, brain-based indices of consciousness in behaviorally unresponsive patients represents a challenge due to the impossibility of obtaining independent evidence through subjective reports. Here we address this problem by first validating a promising metric of consciousness-the Perturbational Complexity Index (PCI)-in a benchmark population who could confirm the...
Scientific Reports
August 5, 2016
Jaakko O. Nieminen, Olivia Gosseries, Marcello Massimini et al.
60 citations
When subjects become unconscious, there is a characteristic change in the way the cerebral cortex responds to perturbations, as can be assessed using transcranial magnetic stimulation and electroencephalography (TMS-EEG). For instance, compared to wakefulness, during non-rapid eye movement (NREM) sleep TMS elicits a larger positive-negative wave, fewer phase-locked oscillations, and an overall...
PLoS One
May 13, 2015
Melanie Boly, Shuntaro Sasai, Olivia Gosseries et al.
69 citations
A meaningful set of stimuli, such as a sequence of frames from a movie, triggers a set of different experiences. By contrast, a meaningless set of stimuli, such as a sequence of 'TV noise' frames, triggers always the same experience--of seeing 'TV noise'--even though the stimuli themselves are as different from each other as the movie frames. We reasoned that the differentiation of cortical...
Brain Injury
August 1, 2014
Martino Napolitani, Olivier Bodart, Paola Canali et al.
44 citations
BACKGROUND: This review discusses the advantages of transcranial magnetic stimulation combined with high-density electroencephalography (TMS-hdEEG) over other current techniques of brain imaging. METHODS AND RESULTS: Its application was reviewed, focusing particularly on disorders of consciousness, in the perspective of recent theories of consciousness. Assessment of non-communicative patients...
Clinical EEG and Neuroscience
2014
Simone Sarasso, Mario Rosanova, Adenauer G. Casali et al.
164 citations
We normally assess another individual's level of consciousness based on her or his ability to interact with the surrounding environment and communicate. Usually, if we observe purposeful behavior, appropriate responses to sensory inputs, and, above all, appropriate answers to questions, we can be reasonably sure that the person is conscious. However, we know that consciousness can be entirely...
Science Translational Medicine
August 14, 2013
Adenauer G. Casali, Olivia Gosseries, Mario Rosanova et al.
1,299 citations
One challenging aspect of the clinical assessment of brain-injured, unresponsive patients is the lack of an objective measure of consciousness that is independent of the subject's ability to interact with the external environment. Theoretical considerations suggest that consciousness depends on the brain's ability to support complex activity patterns that are, at once, distributed among...
Science (New York, N.Y.)
May 13, 2011
Melanie Boly, Marta Isabel Garrido, Olivia Gosseries et al.
Frontoparietal cortex is involved in the explicit processing (awareness) of stimuli. Frontoparietal activation has also been found in studies of subliminal stimulus processing. We hypothesized that an impairment of top-down processes, involved in recurrent neuronal message-passing and the generation of long-latency electrophysiological responses, might provide a more reliable correlate of...
Medecine sciences : M/S
January 2011
Marie Thonnard, Melanie Boly, Marie-Aurélie Bruno et al.
Vegetative and minimally conscious states diagnosis remained a major clinical challenge. New paradigms such as measurement of the global cerebral metabolism, the structural and functional integrity of fronto-parietal network, or the spontaneous activity in resting state have been shown to be helpful to disentangle vegetative from minimally conscious patients. Active neuroimagery paradigms also...
SSRN Electronic Journal
Robin Sandell, Adele Lafrance, Olivia Gosseries et al.
Current spinal cord injury treatments primarily manage symptoms rather than promote neurological recovery. Psilocybin enhances neuroplasticity through 5-HT2A agonism and brain-derived neurotrophic factor upregulation, suggesting therapeutic potential for spinal cord injury rehabilitation. We conducted semi-structured interviews with three individuals who had incomplete spinal cord injuries...