Consciousness and cognition arise from the ongoing interactions between brain regions. Synchronous fluctuations of fMRI signals may indicate that two brain regions perform similar cognitive functions, but neural interactions are also constrained by anatomical connectivity and regions’ molecular, cytoarchitectonic, and metabolic profiles. Here we disentangle the respective contributions of...
Hypnosis is increasingly used in clinical contexts to improve pain management and is supported by experimental research, showing reduced pain perception to controlled nociceptive stimuli. This study investigated spatial selectivity of focused hypnotic analgesia (FHA), a technique used to reduce pain in one restricted body part. Series of brief contact heat stimuli were applied randomly to the...
Non-ordinary states of consciousness (NOC) provide an opportunity to experience highly intense, unique, and perceptually rich subjective states. The neural mechanisms supporting these experiences remain poorly understood. This study examined brain activity associated with a self-induced, substance-free NOC known as Auto-Induced Cognitive Trance (AICT). Twenty-seven trained participants...
Ketamine, in doses suitable to induce anaesthesia in humans, gives rise to a unique state of unresponsiveness accompanied by vivid experiences and sensations, making it possible to disentangle the correlated but distinct concepts of conscious awareness and behavioural responsiveness. This distinction is often overlooked in the study of consciousness. The mathematical framework of connectome...
Auto-induced cognitive trance (AICT) is a method for voluntarily entering modified state of consciousness. The therapeutic implications of AICT are still unknown. Since complementary approaches based on modified states of consciousness are recognized to be beneficial for patients suffering from chronic pain (e.g., hypnosis, meditation), we here present the first case report of a 68-year-old man...
Non-ordinary states of consciousness offer a unique opportunity to explore the interplay between phenomenological experiences and physiological processes. This study investigated individual differences in phenomenological and autonomic nervous system changes between a resting state condition and a non-ordinary state of consciousness (auto-induced cognitive trance, AICT). Specifically, it...
Mystical-type experiences can be induced through techniques like hypnosis and meditation. These experiences are common in near-death experiences (NDEs) and have been linked to paranormal beliefs. This study explored auto-induced cognitive trance (AICT) as a method to induce mystical-type experiences and NDE outside of life threatening situations (NDE-like), as well as examining the influence of...
Shamanism is a spiritual tradition in which trance practitioners deliberately modify their state of consciousness to seemingly interact with an invisible world to resolve their community members' problems. This review aims to provide a multidisciplinary overview of scientific research on shamanic trance. The search was performed using PubMed and Google Scholar databases. Twenty-seven articles...
Abstract Ketamine is classified as a dissociative anaesthetic that, in sub-anaesthetic doses, can produce an altered state of consciousness characterised by dissociative symptoms, visual and auditory hallucinations, and perceptual distortions. Given the anaesthetic-like and psychedelic-like nature of this compound, it is expected to have different effects on brain dynamics in anaesthetic doses...
High-order interactions are required across brain regions to accomplish specific cognitive functions. These functional interdependencies are reflected by synergistic information that can be obtained by combining the information from all the sources considered and redundant information (i.e., common information provided by all the sources). However, electroencephalogram (EEG) functional...
This review provides an exploration of trance states, covering their phenomenology, neural mechanisms, and clinical uses. Trance states, present in diverse cultural contexts from shamanic practices to modern adaptations, have recently captured the interest of researchers and clinicians. Here, we delve into the phenomenological aspects of trance experiences, highlighting the most common...
Trance states include various practices characterized by a modulation of consciousness, but with their own specific characteristics and induction techniques. They have been very seldom scientifically studied, and their phenomenological similarities and differences are poorly documented. This paper will focus on two types of Western trances developed after the leaders were trained in traditional...
When used separately, virtual reality (VR) and mind-body therapies (MBTs) have the potential to reduce pain across various acute and chronic conditions. While their combination is increasingly used, no study offers a consolidated presentation of VR and MBTs. This study aims to propose an overview of the effectiveness of VR combined with MBTs (i.e., meditation, mindfulness, relaxation, and...
Auto-induced cognitive trance (AICT) is a modified state of consciousness derived from shamanic tradition that can be practised by individuals after specific training. The aim of this work was to characterize the phenomenological experiences of AICT, using text mining analysis. Free recalls of subjective experiences were audio-recorded in 27 participants after five pseudo-randomized...
Self-induced cognitive trance (SICT) is a voluntary non-ordinary state of consciousness characterized by a lucid yet narrowed awareness of the external surroundings. It involves a hyper-focused immersive experience of flow, expanded inner imagery, modified somatosensory processing, and an altered perception of self and time. SICT is gaining attention due to its potential clinical applications....
To understand how pharmacological interventions can exert their powerful effects on brain function, we need to understand how they engage the brain’s rich neurotransmitter landscape. Here, we bridge microscale molecular chemoarchitecture and pharmacologically induced macroscale functional reorganization, by relating the regional distribution of 19 neurotransmitter receptors and transporters...
Introduction Little is known about the potential personality and psychological predictors of near-death experiences (NDEs), and fewer yet those of near-death-like experiences (NDEs-like; similar phenomenology reported after a non-life-threatening context). This study investigated whether personality traits (Openness, Extraversion, Pleasantness, Conscientiousness, and Neuroticism), dissociative...
Hypnosis has been shown to be of clinical utility; however, its underlying neural mechanisms remain unclear. This study aims to investigate altered brain dynamics during the non-ordinary state of consciousness induced by hypnosis. We studied high-density EEG in 9 healthy participants during eyes-closed wakefulness and during hypnosis, induced by a muscle relaxation and eyes fixation procedure....
No contemporary unifying framework has been provided for the study of non-ordinary states of consciousness (NSCs) despite increased interest in hypnosis, meditation, and psychedelics. NSCs induce shifts in experiential contents (what appears to the experiencer) and/or structure (how it appears). This can allow the investigation of the plastic and dynamic nature of experience from a multiscale...
Abstract To understand how pharmacological interventions can exert their powerful effects on brain function, we need to understand how they engage the brain’s rich neurotransmitter landscape. Here, we bridge microscale molecular chemoarchitecture and pharmacologically-induced macroscale functional reorganisation, by relating the regional distribution of 19 neurotransmitter receptors and...
A symptom cluster is very common among oncological patients: cancer-related fatigue (CRF), emotional distress, sleep difficulties, pain, and cognitive difficulties. Clinical applications of interventions based on non-ordinary states of consciousness, mostly hypnosis and meditation, are starting to be investigated in oncology settings. They revealed encouraging results in terms of improvements...
PURPOSE: Cancer patients often report low self-esteem and high emotional distress. Two factors seem particularly linked to these symptoms: emotion regulation strategies and mindfulness. The interest of hypnosis and self-care to relieve these symptoms is not well documented. Our randomized controlled trial aimed at assessing the effect of a group intervention combining self-hypnosis and...
Cet article vise à comprendre comment les processus impliqués en hypnose peuvent augmenter le confort des patientshospitalisés aux soins intensifs. L’hypnose est un outil de plus en plus utilisé par les équipes médicales comme techniquecomplémentaire aux approches biomédicales usuelles. De nombreuses études ont démontré ses effets dans différentscontextes (chirurgie, douleurs chroniques,...
Hypnosis is a modified state of consciousness widely used to decrease pain perception in research protocols and clinical practice. In recent decades, hypnosis has been increasingly proposed to patients to re-engage their resources and capacities to modulate pain and emotional distress and to improve their treatment and recovery of well-being. Neuroimaging research helps clinicians to understand...
https://doi.org/10.1016/j.clinph.2019.11.011 1388-2457/ 2019 The Authors. Published by Elsevier B.V. on behalf of In This is an open access article under the CC BY-NC-ND license (http://creativ Cognitive trance is defined as a volitional, purposeful and selfinduced modified state of consciousness (inherited from shamanic traditional practice), characterized by lucid but narrowed awareness of...