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Didier Ledoux

7 papers in the library · 417 citations · publishing 2009-2025

Papers

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Brain Injury and Ketamine study (BIKe): a prospective, randomized controlled double blind clinical trial to study the effects of ketamine on therapy intensity level and intracranial pressure in severe traumatic brain injury patients.

Trials May 28, 2025 Veerle De Sloovere, Liese Mebis, Pieter Wouters et al. 9 citations

In severe traumatic brain injury (TBI), sedatives are often used to control intracranial pressure (ICP), to reduce brain metabolism, to allow for other treatments such as mechanical ventilation or targeted temperature management, or to control paroxysmal sympathetic hyperactivity. Prolonged sedation is often necessary. The most commonly used sedatives in TBI are propofol and midazolam, often in...

EEG signature of near-death-like experiences during syncope-induced periods of unresponsiveness.

Neuroimage September 1, 2024 Charlotte Martial, Andrea Piarulli, Olivia Gosseries et al. 10 citations

During fainting, disconnected consciousness may emerge in the form of dream-like experiences. Characterized by extra-ordinary and mystical features, these subjective experiences have been associated to near-death-like experiences (NDEs-like). We here aim to assess brain activity during syncope-induced disconnected consciousness by means of high-density EEG monitoring. Transient loss of...

Mapping the functional brain state of a world champion freediver in static dry apnea

Brain Structure and Function 2021 Jitka Annen, Rajanikant Panda, Charlotte Martial et al. 15 citations

peer reviewedVoluntary apnea showcases extreme human adaptability in trained individuals like professional free divers. We evaluated the psychological and physiological adaptation and the functional cerebral changes using electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI) to 6.5 min of dry static apnea performed by a world champion free diver. Compared to resting...

L’hypnose a-t-elle sa place en réanimation ?

Médecine Intensive Réanimation July 30, 2020 Floriane Rousseaux, Aminata Bicego, Christophe Malengreaux et al. 2 citations

Cet article vise à comprendre comment les processus impliqués en hypnose peuvent augmenter le confort des patientshospitalisés aux soins intensifs. L’hypnose est un outil de plus en plus utilisé par les équipes médicales comme techniquecomplémentaire aux approches biomédicales usuelles. De nombreuses études ont démontré ses effets dans différentscontextes (chirurgie, douleurs chroniques,...

Near-death experiences in non-life-threatening events and coma of different etiologies

Frontiers in Human Neuroscience May 27, 2014 Vanessa Charland-Verville, Jean-Pierre Jourdan, Marie Thonnard et al. 116 citations

BACKGROUND: Near death experiences (NDEs) are increasingly being reported as a clearly identifiable physiological and psychological reality of clinical significance. However, the definition and causes of the phenomenon as well as the identification of NDE experiencers is still a matter of debate. To date, the most widely used standardized tool to identify and characterize NDEs in research is...

Characteristics of Near-Death Experiences Memories as Compared to Real and Imagined Events Memories

PLoS One March 27, 2013 Marie Thonnard, Vanessa Charland-Verville, Serge Brédart et al. 140 citations

Since the dawn of time, Near-Death Experiences (NDEs) have intrigued and, nowadays, are still not fully explained. Since reports of NDEs are proposed to be imagined events, and since memories of imagined events have, on average, fewer phenomenological characteristics than real events memories, we here compared phenomenological characteristics of NDEs reports with memories of imagined and real...

Dualism Persists in the Science of Mind

Annals of the New York Academy of Sciences March 1, 2009 Athena Demertzi, Charlene Liew, Didier Ledoux et al. 125 citations

The relationship between mind and brain has philosophical, scientific, and practical implications. Two separate but related surveys from the University of Edinburgh (University students, n= 250) and the University of Liège (health-care workers, lay public, n= 1858) were performed to probe attitudes toward the mind-brain relationship and the variables that account for differences in views. Four...