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Minji Lee

5 papers in the library · 231 citations · publishing 2019-2025

Papers

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A pilot human study using ketamine to treat disorders of consciousness.

iScience January 17, 2025 Paolo Cardone, Arthur Bonhomme, Vincent Bonhomme et al. 9 citations

Post-comatose disorders of consciousness (DoC) represent persistent neurological conditions with limited therapeutic options and a poor prognosis. Recent works advocate for exploring the effects of psychedelics to enhance brain complexity in DoC and ameliorate their consciousness. We investigated sub-anesthetic concentration of the atypical psychedelic ketamine for treating post-comatose...

Quantifying arousal and awareness in altered states of consciousness using interpretable deep learning

Nature Communications February 25, 2022 Minji Lee, Leandro R. D. Sanz, Alice Barra et al. 120 citations

Consciousness can be defined by two components: arousal (wakefulness) and awareness (subjective experience). However, neurophysiological consciousness metrics able to disentangle between these components have not been reported. Here, we propose an explainable consciousness indicator (ECI) using deep learning to disentangle the components of consciousness. We employ electroencephalographic (EEG)...

Effective Correlates of Motor Imagery Performance based on Default Mode Network in Resting-State

arXiv Preprint Archive February 11, 2020 Jae-Geun Yoon, Minji Lee

Motor imagery based brain-computer interfaces (MI-BCIs) allow the control of devices and communication by imagining different muscle movements. However, most studies have reported a problem of "BCI-illiteracy" that does not have enough performance to use MI-BCI. Therefore, understanding subjects with poor performance and finding the cause of performance variation is still an important...

Graph Theoretical Analysis of Cortical Networks based on Conscious Experience.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference July 1, 2019 Minji Lee, Benjamin Baird, Olivia Gosseries et al. 4 citations

The aim of the study was to investigate differences in cortical networks based on the state of consciousness. Five subjects performed a serial-awakening paradigm with electroencephalography (EEG) recordings. We considered four states of consciousness: (1) non-rapid eye movement (NREM) sleep with no conscious experience, (2) NREM sleep with conscious experience, (3) rapid eye movement (REM)...

Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS–EEG study

Scientific Reports March 26, 2019 Minji Lee, Benjamin Baird, Olivia Gosseries et al. 98 citations

The neuronal connectivity patterns that differentiate consciousness from unconsciousness remain unclear. Previous studies have demonstrated that effective connectivity, as assessed by transcranial magnetic stimulation combined with electroencephalography (TMS-EEG), breaks down during the loss of consciousness. This study investigated changes in EEG connectivity associated with consciousness...