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Jaakko O. Nieminen

5 papers in the library · 331 citations · publishing 2016-2022

Papers

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Quantifying arousal and awareness in altered states of consciousness using interpretable deep learning

Nature Communications February 25, 2022 Minji Lee, Leandro R. D. Sanz, Alice Barra et al. 120 citations

Consciousness can be defined by two components: arousal (wakefulness) and awareness (subjective experience). However, neurophysiological consciousness metrics able to disentangle between these components have not been reported. Here, we propose an explainable consciousness indicator (ECI) using deep learning to disentangle the components of consciousness. We employ electroencephalographic (EEG)...

Graph Theoretical Analysis of Cortical Networks based on Conscious Experience.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference July 1, 2019 Minji Lee, Benjamin Baird, Olivia Gosseries et al. 4 citations

The aim of the study was to investigate differences in cortical networks based on the state of consciousness. Five subjects performed a serial-awakening paradigm with electroencephalography (EEG) recordings. We considered four states of consciousness: (1) non-rapid eye movement (NREM) sleep with no conscious experience, (2) NREM sleep with conscious experience, (3) rapid eye movement (REM)...

Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS–EEG study

Scientific Reports March 26, 2019 Minji Lee, Benjamin Baird, Olivia Gosseries et al. 98 citations

The neuronal connectivity patterns that differentiate consciousness from unconsciousness remain unclear. Previous studies have demonstrated that effective connectivity, as assessed by transcranial magnetic stimulation combined with electroencephalography (TMS-EEG), breaks down during the loss of consciousness. This study investigated changes in EEG connectivity associated with consciousness...

Evoked Alpha Power is Reduced in Disconnected Consciousness During Sleep and Anesthesia

Scientific Reports November 5, 2018 Matthieu Darracq, Chadd M. Funk, Daniel Polyakov et al. 49 citations

Sleep and anesthesia entail alterations in conscious experience. Conscious experience may be absent (unconsciousness) or take the form of dreaming, a state in which sensory stimuli are not incorporated into conscious experience (disconnected consciousness). Recent work has identified features of cortical activity that distinguish conscious from unconscious states; however, less is known about...

Consciousness and cortical responsiveness: a within-state study during non-rapid eye movement sleep

Scientific Reports August 5, 2016 Jaakko O. Nieminen, Olivia Gosseries, Marcello Massimini et al. 60 citations

When subjects become unconscious, there is a characteristic change in the way the cerebral cortex responds to perturbations, as can be assessed using transcranial magnetic stimulation and electroencephalography (TMS-EEG). For instance, compared to wakefulness, during non-rapid eye movement (NREM) sleep TMS elicits a larger positive-negative wave, fewer phase-locked oscillations, and an overall...