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Anne Maj van der Velden

7 papers in the library · 5 citations · publishing 2023-2026

Papers

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Complex harmonic manifolds in mindfulness-based cognitive therapy for major depressive disorder

medRxiv July 8, 2026 Paulina Clara Dagnino, Anne Maj van der Velden, Yonatan Sanz Perl et al. preprint

Major depressive disorder (MDD) is a heterogeneous mental disorder characterised by rumination. Mindfulness-based cognitive therapy (MBCT) is an evidence-based treatment developed to target rumination and recurrence risk. Ongoing studies have begun to identify neural changes associated with treatment effects. However, the low-dimensional organisation underlying whole-brain dynamics remains...

Changes in hierarchical brain dynamics of rumination following mindfulness-based cognitive therapy for depression

medRxiv June 23, 2026 Paulina Clara Dagnino, Anne Maj van der Velden, Henricus G. Ruhé et al. preprint

Abstract Major depressive disorder (MDD) is a leading cause of disability worldwide with risk of onset and recurrence linked to depressive ruminative thought patterns. Mindfulness-based cognitive therapy (MBCT) is an evidence-based treatment for depression that targets the ability to recognise, decenter, and disengage from ruminative thought patterns. Elucidating how MBCT impacts hierarchical...

Dynamic Repertoire of Brain Networks in Mindfulness-Based Cognitive Therapy During Rumination: A Randomized Controlled Trial

Biological Psychiatry Global Open Science May 14, 2026 Anne Maj van der Velden, Jakub Vohryzek, Paulina Clara Dagnino et al.

BACKGROUND Depression is a prevalent and debilitating affective disorder characterised by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for recurrent depression developed specifically to target rumination and recurrence risk by training metacognitive awareness and adaptive attention, emotion and self-regulation...

DOI: 10.1016/j.bpsgos.2026.100753 (opens in new tab) Mindfulness Randomized controlled trial Cognition Repertoire +3

Examining what works for whom and how in mindfulness-based cognitive therapy (MBCT) for recurrent depression: moderated-mediation analysis in the PREVENT trial.

The British Journal of Psychiatry April 1, 2025 Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al. 4 citations

Personalised management of recurrent depression, considering individual patient characteristics, is crucial. This study evaluates the potentially different mediating role of mindfulness skills in managing recurrent depression using mindfulness-based cognitive therapy (MBCT) among people with varying depression severity. Data from the Prevention of Depressive Relapse or Recurrence (PREVENT)...

DOI: 10.1192/bjp.2024.178 (opens in new tab) Full text (opens in new tab) Recurrent depression Depression severity Mindfulness skills Mindfulness-based cognitive therapy +1

Dynamical repertoire of brain networks in mindfulness cognitive behavioural therapy during rumination: A randomized controlled trial

medRxiv February 7, 2025 Jakub Vohryzek, Anne Maj van der Velden, Willem Kuyken et al. 1 citation preprint

BACKGROUND: Depression is a prevalent and debilitating affective disorder characterised by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for recurrent depression developed specifically to target rumination and recurrence risk by training metacognitive awareness and adaptive attention, emotion and self-regulation...

Mindfulness Training Changes Brain Dynamics During Depressive Rumination: A Randomized Controlled Trial.

Biological Psychiatry February 1, 2023 Anne Maj van der Velden, Jacqueline Scholl, Else-Marie Elmholdt et al.

Depression is a leading cause of disability worldwide and its prevalence is on the rise. One of the most debilitating aspects of depression is the dominance and persistence of depressive rumination, a state of mind that is linked to onset and recurrence of depression. Mindfulness meditation trains adaptive attention regulation and present-moment embodied awareness, skills that may be...

Examining What Works for Whom and How in Mindfulness-Based Cognitive Therapy (MBCT) for Recurrent Depression: A Moderated-Mediation Analysis in the PREVENT Trial (in press)

Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al. preprint

Background: Personalized management of recurrent depression, considering individual patient characteristics, is crucial. Aims: This study evaluates the potentially different mediating role of mindfulness skills in managing recurrent depression using mindfulness-based cognitive therapy (MBCT) among patients with varying depression severity. Method: Data from the PREVENT trial, comparing MBCT...