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Anil K. Seth

University of Sussex, Canadian Institute for Advanced Research

72 papers in the library · 9,166 citations · publishing 1998-2026

Papers

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From Generative Models to Generative Passages: A Computational Approach to (Neuro) Phenomenology.

Review of Philosophy and Psychology 2022 Maxwell J D Ramstead, Anil K. Seth, Casper Hesp et al. 75 citations

This paper presents a version of neurophenomenology based on generative modelling techniques developed in computational neuroscience and biology. Our approach can be described as computational phenomenology because it applies methods originally developed in computational modelling to provide a formal model of the descriptions of lived experience in the phenomenological tradition of philosophy...

The Phenomenological Control Scale: Measuring the Capacity for Creating Illusory Nonvolition, Hallucination and Delusion

Collabra Psychology 2021 Peter Lush, R. B. Y. Scott, Anil K. Seth et al. 35 citations

Phenomenological control is the ability to generate experiences to meet expectancies. There are stable trait differences in this ability, as shown by responses to imaginative suggestions of, for example, paralysis, amnesia, and auditory, visual, gustatory and tactile hallucinations. Phenomenological control has primarily been studied within the context of hypnosis, in which suggestions are...

Predictive processing as an empirical theory for consciousness science.

Cognitive Neuroscience 2021 Anil K. Seth, Jakob Hohwy

The theories of consciousness discussed by Doerig and colleagues tend to monolithically identify consciousness with some other phenomenon, process, or mechanism. But by treating consciousness as singular explanatory target, such theories will struggle to account for the diverse properties that conscious experiences exhibit. We propose that progress in consciousness science will best be achieved...

Predictive processing as a systematic basis for identifying the neural correlates of consciousness

Philosophy and the Mind Sciences December 30, 2020 Jakob Hohwy, Anil K. Seth 162 citations

The search for the neural correlates of consciousness is in need of a systematic, principled foundation that can endow putative neural correlates with greater predictive and explanatory value. Here, we propose the predictive processing framework for brain function as a promising candidate for providing this systematic foundation. The proposal is motivated by that framework’s ability to address...

Trait phenomenological control predicts experience of mirror synaesthesia and the rubber hand illusion

Nature Communications September 25, 2020 Peter Lush, Vanessa Botan, R. B. Y. Scott et al. 136 citations

In hypnotic responding, expectancies arising from imaginative suggestion drive striking experiential changes (e.g., hallucinations) - which are experienced as involuntary - according to a normally distributed and stable trait ability (hypnotisability). Such experiences can be triggered by implicit suggestion and occur outside the hypnotic context. In large sample studies (of 156, 404 and 353...

Extensive Phenomenological Overlap between Induced and Naturally-Occurring Synaesthetic Experiences

bioRxiv Preprint Server August 3, 2020 David J. Schwartzman, Aleš Oblak, Nicolas Rothen et al. 4 citations preprint

Grapheme-colour synaesthesia (GCS) is defined by additional perceptual experiences, which are automatically and consistently triggered by specific inducing stimuli. The associative nature of GCS has motivated attempts to induce synaesthesia by means of associative learning. Two recent studies have shown that extensive associative training can generate not only behavioural (consistency and...

Phenomenological control as cold control.

Psychology of Consciousness Theory Research and Practice June 25, 2020 Zoltan Dienes, Peter Lush, Bence Pálfi et al. 42 citations

We first review recent work from our laboratory, which construes hypnotizability as an example of a more general trait of capacity for phenomenological control, which people can use to create subjective experiences in many nonhypnotic contexts where those experiences fulfill people's goals. Second, we review recent work, which construes phenomenological control as a specifically metacognitive...

Split-Brain: What We Know Now and Why This is Important for Understanding Consciousness

Neuropsychology Review May 12, 2020 Edward H.F. de Haan, Paul M. Corballis, Steven A. Hillyard et al. 86 citations

Recently, the discussion regarding the consequences of cutting the corpus callosum ("split-brain") has regained momentum (Corballis, Corballis, Berlucchi, & Marzi, Brain, 141(6), e46, 2018; Pinto et al., Brain, 140(5), 1231-1237, 2017a; Pinto, Lamme, & de Haan, Brain, 140(11), e68, 2017; Volz & Gazzaniga, Brain, 140(7), 2051-2060, 2017; Volz, Hillyard, Miller, & Gazzaniga, Brain, 141(3), e15,...

Decreased directed functional connectivity in the psychedelic state.

Neuroimage December 17, 2019 Lionel Barnett, Suresh Muthukumaraswamy, Robin Carhart-Harris et al. 88 citations

Neuroimaging studies of the psychedelic state offer a unique window onto the neural basis of conscious perception and selfhood. Despite well understood pharmacological mechanisms of action, the large-scale changes in neural dynamics induced by psychedelic compounds remain poorly understood. Using source-localised, steady-state MEG recordings, we describe changes in functional connectivity...

Are There Islands of Awareness?

Trends in Neurosciences December 10, 2019 Tim Bayne, Anil K. Seth, Marcello Massimini 146 citations

Awareness may persist in fully disconnected cortical islands.We identify both natural and artificial examples of potential islands of awareness.Detecting islands of awareness poses difficult but often addressable challenges.The possibility of islands of awareness raises important ethical and legal issues.The discovery of islands of awareness would have important implications for debates about...

Neurophenomenology of induced and natural synaesthesia.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences December 9, 2019 David J. Schwartzman, Daniel Bor, Nicolas Rothen et al. 7 citations

People with synaesthesia have additional perceptual experiences, which are automatically and consistently triggered by specific inducing stimuli. Synaesthesia therefore offers a unique window into the neurocognitive mechanisms underlying conscious perception. A long-standing question in synaesthesia research is whether it is possible to artificially induce non-synaesthetic individuals to have...

Increased spontaneous EEG signal diversity during stroboscopically-induced altered states of consciousness

bioRxiv (Cold Spring Harbor Laboratory) January 4, 2019 David J. Schwartzman, Michael Schartner, Benjamin B. Ador et al. 31 citations preprint

Abstract What are the global neuronal signatures of altered states of consciousness (ASC)? Recently, increases in neural signal diversity, compared to those found in wakeful rest, have been reported during psychedelic states. Neural signal diversity has previously been identified as a robust signature of the state of consciousness, showing lower scores during sleep or anaesthesia compared to...

Measuring Integrated Information: Comparison of Candidate Measures in Theory and Simulation.

Entropy (Basel, Switzerland) December 25, 2018 Pedro A. M. Mediano, Anil K. Seth, Adam B. Barrett

Integrated Information Theory (IIT) is a prominent theory of consciousness that has at its centre measures that quantify the extent to which a system generates more information than the sum of its parts. While several candidate measures of integrated information (" Φ ") now exist, little is known about how they compare, especially in terms of their behaviour on non-trivial network models. In...

Measuring Integrated Information: Comparison of Candidate Measures in Theory and Simulation

arXiv Preprint Archive June 25, 2018 Pedro A. M. Mediano, Anil K. Seth, Adam B. Barrett

Integrated Information Theory (IIT) is a prominent theory of consciousness that has at its centre measures that quantify the extent to which a system generates more information than the sum of its parts. While several candidate measures of integrated information (`$Φ$') now exist, little is known about how they compare, especially in terms of their behaviour on non-trivial network models. In...

Impairment of perceptual metacognitive accuracy and reduced prefrontal grey matter volume in first-episode psychosis

Cognitive Neuropsychiatry February 27, 2018 Geoff Davies, Charlotte L. Rae, Sarah N. Garfinkel et al. 23 citations

INTRODUCTION: Metacognition, or "thinking about thinking", is a higher-order thought process that allows for the evaluation of perceptual processes for accuracy. Metacognitive accuracy is associated with the grey matter volume (GMV) in the prefrontal cortex (PFC), an area also impacted in schizophrenia. The present study set out to investigate whether deficits in metacognitive accuracy are...

Loss of consciousness is related to hyper-correlated gamma-band activity in anesthetized macaques and sleeping humans.

Neuroimage February 15, 2018 Michał Bola, Adam B. Barrett, Andrea Pigorini et al.

Loss of consciousness can result from a wide range of causes, including natural sleep and pharmacologically induced anesthesia. Important insights might thus come from identifying neuronal mechanisms of loss and re-emergence of consciousness independent of a specific manipulation. Therefore, to seek neuronal signatures of loss of consciousness common to sleep and anesthesia we analyzed...

Consciousness: The last 50 years (and the next).

Brain and neuroscience advances 2018 Anil K. Seth

The mind and brain sciences began with consciousness as a central concern. But for much of the 20th century, ideological and methodological concerns relegated its empirical study to the margins. Since the 1990s, studying consciousness has regained a legitimacy and momentum befitting its status as the primary feature of our mental lives. Nowadays, consciousness science encompasses a rich...

A Deep-Dream Virtual Reality Platform for Studying Altered Perceptual Phenomenology

Scientific Reports November 16, 2017 Keisuke Suzuki, Warrick Roseboom, David J. Schwartzman et al. 111 citations

Altered states of consciousness, such as psychotic or pharmacologically-induced hallucinations, provide a unique opportunity to examine the mechanisms underlying conscious perception. However, the phenomenological properties of these states are difficult to isolate experimentally from other, more general physiological and cognitive effects of psychoactive substances or psychopathological...

The Hallucination Machine: A Deep-Dream VR platform for Studying the Phenomenology of Visual Hallucinations

bioRxiv Preprint Server November 3, 2017 Keisuke Suzuki, Warrick Roseboom, David J. Schwartzman et al. 2 citations preprint

Altered states of consciousness, such as psychotic or pharmacologically-induced hallucinations, provide a unique opportunity to examine the mechanisms underlying conscious perception. However, the phenomenological properties of these states are difficult to isolate experimentally from other, more general physiological and cognitive effects of psychoactive substances or psychopathological...

Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin

Scientific Reports April 19, 2017 Michael Schartner, Robin Carhart-Harris, Adam B. Barrett et al. 450 citations

Abstract What is the level of consciousness of the psychedelic state? Empirically, measures of neural signal diversity such as entropy and Lempel-Ziv (LZ) complexity score higher for wakeful rest than for states with lower conscious level like propofol-induced anesthesia. Here we compute these measures for spontaneous magnetoencephalographic (MEG) signals from humans during altered states of...

Conscious visual memory with minimal attention.

Journal of Experimental Psychology General January 30, 2017 Yair Pinto, Annelinde R. E. Vandenbroucke, Marte Otten et al. 23 citations

Is conscious visual perception limited to the locations that a person attends? The remarkable phenomenon of change blindness, which shows that people miss nearly all unattended changes in a visual scene, suggests the answer is yes. However, change blindness is found after visual interference (a mask or a new scene), so that subjects have to rely on working memory (WM), which has limited...

Global and local complexity of intracranial EEG decreases during NREM sleep

Neuroscience of Consciousness January 27, 2017 Michael Schartner, Andrea Pigorini, Steve A. Gibbs et al. 158 citations

Key to understanding the neuronal basis of consciousness is the characterization of the neural signatures of changes in level of consciousness during sleep. Here we analysed three measures of dynamical complexity on spontaneous depth electrode recordings from 10 epilepsy patients during wakeful rest (WR) and different stages of sleep: (i) Lempel-Ziv complexity, which is derived from how...

Active interoceptive inference and the emotional brain

Philosophical Transactions of the Royal Society B Biological Sciences October 11, 2016 Anil K. Seth, Karl Friston 936 citations

We review a recent shift in conceptions of interoception and its relationship to hierarchical inference in the brain. The notion of interoceptive inference means that bodily states are regulated by autonomic reflexes that are enslaved by descending predictions from deep generative models of our internal and external milieu. This re-conceptualization illuminates several issues in cognitive and...

Rhythmic Influence of Top–Down Perceptual Priors in the Phase of Prestimulus Occipital Alpha Oscillations

Journal of Cognitive Neuroscience April 15, 2016 Maxine T. Sherman, Ryota Kanai, Anil K. Seth et al. 134 citations

Prior expectations have a powerful influence on perception, biasing both decision and confidence. However, how this occurs at the neural level remains unclear. It has been suggested that spontaneous alpha-band neural oscillations represent rhythms of the perceptual system that periodically modulate perceptual judgments. We hypothesized that these oscillations instantiate the effects of...

Why fish pain cannot and should not be ruled out

Animal Sentience 2016 Anil K. Seth 49 citations

Do fish consciously feel pain? Addressing this question, Key (2016) asks whether the neural mechanisms underlying conscious pain reports in humans can be identified in fish. This strategy fails in three ways. First, non-mammalian consciousness — if it exists — may depend on different mechanisms. Second, accumulating neurophysiological and behavioural evidence, evolutionary considerations, and...