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Computational biology and chemistry

ISSN 1476-928X

2 papers in the library · 11 citations · publishing 2023

Papers

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The marijuana-schizophrenia multifaceted nexus: Connections and conundrums towards neurophysiology.

Computational biology and chemistry December 2023 Pukar Khanal, Vishal S Patil, B M Patil et al.

Delta-9-tetrahydrocannabinol, a component of marijuana, interacts with cannabinoid receptors in brain involved in memory, cognition, and emotional control. However, marijuana use and schizophrenia development is a complicated and contentious topic. As a result, more investigation is needed to understand this relationship. Through the functional enrichment analysis, we report the...

In silico characterization of the psilocybin biosynthesis pathway.

Computational biology and chemistry June 1, 2023 William Irvine, Marshall Tyler, Rupika Delgoda 11 citations

Nearly all mushrooms of the Psilocybe genus contain the natural product psilocybin, which is a psychoactive alkaloid derived from l-tryptophan. Considering their use in ancient times, as well as their psychedelic properties, these mushrooms have re-emerged with psychotherapeutic potential for treating depression, which has triggered increased pharmaceutical interest. However, the psilocybin...