The Canadian Journal of Psychiatry
November 1, 1980
Angus S. Mcdonald
11 citations
This article reviews the major hallucinogenic fungi both for their historical as well as neurochemical import. Despite voluminous literature on them, relatively little study has focused on psilocybin related substances that could relate to forms of psychotic illness. Some metabolic pathways are reviewed which illustrate the need for more study of indole compounds such as baeocystin.
Scottish Medical Journal
October 1, 1979
Peter R. Mills, D. Lesinskas, G Watkinson
18 citations
There has been a revival of interest amongst young people in the raw consumption of ‘wild’ Psilocybin mushrooms, because of their hallucinogenic properties. Seven cases of mushroom overdosage are described. Whilst the hallucinogenic mushrooms are relatively harmless, the dangers from inadvertent ingestion of commonly occurring poisonous varieties are emphasised.
Pediatrics in Review
July 1, 1979
S. Cohen
5 citations
Phencyclidine (1-[1-phenylcyclohexyl]piperidine, PCP, hog, sheets, angel dust, Sernylan, and many other common names) is a primate anesthetic that has emerged as a common drug of abuse and as a medical emergency problem during the past few years. Phencyclidine abuse is primarily a youthful activity. It is associated with multiple clinical states, an unusual amount of aggressive behavior, and a...
Journal of Pharmacology and Experimental Therapeutics
December 1, 1978
Mark A. Geyer, Lyle R. Petersen, Gary J. Rose et al.
69 citations
Tactile startle responding by male Sprague-Dawley rats given 60 presentations of air-puff stimuli (37.5 psi) was measured after the intraperitoneal administration of graded doses of hallucinogens and other psychoactive drugs. Among the drugs tested were the indoleamine-derived compounds, lysergic acid diethylamide (LSD), N,N-dimethyltryptamine and psilocin, and the phenylethylamine-derived...
Perceptual and Motor Skills
December 1, 1976
Kristian Holt‐hansen
51 citations
9 Ss were requested to perceive simultaneously the taste of beer and a rhythmic sound, the pitch of which could be varied. The frequencies at which Ss experienced harmony between the taste and the sound were determined. At the pitch of harmony Ss reported characteristic experiences, e.g., optimum taste of the beer, rhythmic sensations in the head, and tickling sensations in the jaws and the...
Science
November 12, 1976
Barry L. Jacobs, Michael E. Trulson, Warren C. Stern
72 citations
Cats injected with LSD (d-lysergic acid diethylamide) exhibit a group of behaviors that appear to be specific to hallucinogenic drugs. Two of these behaviors, limb flick and abortive grooming, have an extremely low frequency of occurrence in normal cats, but often dominate the behavior of LSD-treated cats. The frequency of occurrence of this group of behaviors is related to the dose of LSD. The...
Psychopharmacology
1975
Brenda K. Colasanti, Naim Khazan
14 citations
Recordings of the electroencephalogram (EEG) and the electromyogram (EMG) were collected continuously from rats equipped with permanent cortical and temporalis muscle electrodes. Automatic injections of mescaline were administered through indwelling i.p. cannulas at an initial dose of 30 mg/kg every 6 hrs for the first 2 days. This dose was then increased to 60 mg/kg 6 hr which was given for...
Pharmacopsychiatry
1975
Roland A. Fischer, Hy Goldman
4 citations
D-lysergic acid diethylamide (LSD) displays (1) the phenylethylamine pattern present in mescaline, cyclazocine and catecholamines and (2) the 4-substituted tryptamine structure of psilocybin which is a serotonin analog. Hence (a) Naloxone--a blocker of the LSD-like side effects of cyclazocine--should (and does) block effects of LSD, and (b) cross-tolerance may be present between LSD and...
JAMA
November 11, 1974
Miles K. Crowder
16 citations
To the Editor.— In a recent issue (229:763, 1974), Shaffer describes a series of cases characterized by anesthesia, analgesia, nystagmus, dizziness, diplopia, visual distortions, and psychosis. These findings were attributed to ketamine, a derivative of phencyclidine. Phencyclidine is a major component of street drug preparations.1In one series, phencyclidine was detected in 184 of 237 street...
Archives of General Psychiatry
July 1, 1974
Solomon H. Snyder
25 citations
Several different molecular conformations of psychedelic drugs have been proposed to explain the very similar effects of drugs with markedly divergent chemical structures, such as mescaline andd-lysergic acid diethylamide (LSD). In some of these models, the α-carbon of methoxyamphetamine psychedelics approximates the asymmetric carbon No. 5 of LSD predicting that the (-) "R" isomer of the...