The Canadian Journal of Psychiatry
September 11, 2026
James Mirabelli, James MacKillop, David Streiner et al.
Background Individuals with borderline personality disorder (BPD) frequently use cannabis, often for self-medication. However, cannabis use has also been linked to BPD symptom severity, suggesting heterogeneity in its effects. Individuals with BPD frequently experience psychotic-like symptoms and may demonstrate elevated psychosis vulnerability, which is associated with greater symptom severity...
The Canadian Journal of Psychiatry
March 25, 2025
Noah Chisamore, Erica Kaczmarek, Zoe Doyle et al.
1 citation
Objective: To compare changes in depression, anxiety, and suicidality symptoms after a single 25 mg oral dose of psilocybin between treatment-resistant depression participants not on antidepressants at screening to participants that discontinued antidepressant medications leading up to receiving psilocybin-assisted psychotherapy (PAP). Methods: Participants (n = 27) received at least one 25 mg...
The Canadian Journal of Psychiatry
August 17, 2022
Joshua D. Rosenblat, Muhammad Ishrat Husain, Yena Lee et al.
58 citations
Objective Serotonergic psychedelics are re-emerging as potential novel treatments for several psychiatric disorders including major depressive disorder. The Canadian Network for Mood and Anxiety Treatments (CANMAT) convened a task force to review the evidence and provide a consensus recommendation for the clinical use of psychedelic treatments for major depressive disorder. Methods A systematic...
The Canadian Journal of Psychiatry
November 11, 2020
Jennifer Swainson, Alexander McGirr, Pierre Blier et al.
109 citations
OBJECTIVE: -methyl-d-aspartate (NMDA) receptor antagonist, has demonstrated rapid antidepressant effects in patients with TRD. The Canadian Network for Mood and Anxiety Treatments (CANMAT) convened a task force to review the evidence for efficacy and safety of racemic ketamine and to provide recommendations for its use in clinical practice. METHODS: A systematic review was conducted with...
The Canadian Journal of Psychiatry
February 1, 2012
Norman A. S. Farb, Adam K. Anderson, Zindel V. Segal
361 citations
Mindfulness involves nonjudgmental attention to present-moment experience. In its therapeutic forms, mindfulness interventions promote increased tolerance of negative affect and improved well-being. However, the neural mechanisms underlying mindful mood regulation are poorly understood. Mindfulness training appears to enhance focused attention, supported by the anterior cingulate cortex and the...
The Canadian Journal of Psychiatry
February 1, 2012
Walter E B Sipe, Stuart J. Eisendrath
283 citations
Mindfulness-based cognitive therapy (MBCT) incorporates elements of cognitive-behavioural therapy with mindfulness-based stress reduction into an 8-session group program. Initially conceived as an intervention for relapse prevention in people with recurrent depression, it has since been applied to various psychiatric conditions. Our paper aims to briefly describe MBCT and its putative...
The Canadian Journal of Psychiatry
April 1, 2011
Emmanuel H During, Fanny M Elahi, Olivier Taieb et al.
84 citations
Objective: Although the Diagnostic and Statistical Manual of Mental Disorders (DSM), Fourth Edition, acknowledges the existence of dissociative trance and possession disorders, simply named dissociative trance disorder (DTD), it asks for further studies to assess its clinical utility in the DSM-5. To answer this question, we conducted the first review of the medical literature. Method: The...
The Canadian Journal of Psychiatry
March 1, 2009
Emmanuel Stip, Geneviève Létourneau
88 citations
This paper reviews the presence of psychotic features in the nonclinical population. The results of a literature review suggest that delusional and hallucinatory experiences are more common in the general population than we may think, and that there could well be a symptomatic continuum between people who have and people who have not been diagnosed with indisputable psychotic disorders. In the...
The Canadian Journal of Psychiatry
April 1, 2007
Tony Toneatto, Linda Nguyen
316 citations
OBJECTIVE: To review the impact of mindfulness-based stress reduction (MBSR) on symptoms of anxiety and depression in a range of clinical populations. METHOD: Our review included any study that was published in a peer-reviewed journal, used a control group, and reported outcomes related to changes in depression and anxiety. We extracted the following key variables from each of the 15 studies...
The Canadian Journal of Psychiatry
August 1, 2006
Louisa Degenhardt, Wayne Hall
Objective: To assess whether cannabis use in adolescence and young adulthood is a contributory cause of schizophreniform psychosis in that it may precipitate psychosis in vulnerable individuals. Method: We reviewed longitudinal studies of adolescents and young adults that examined the relations between self-reported cannabis use and the risk of diagnosis with a psychosis or of reporting...
The Canadian Journal of Psychiatry
August 1, 2006
Wayne Hall, Louisa Degenhardt
Objective: To explore the implications for mental health services, for health education about the risks of cannabis use, and for public policy toward cannabis use of observational evidence that cannabis use is a contributory cause of psychosis. Method: Using comparative analyses of similar evidence for the harmful effects of alcohol, tobacco, and amphetamine use, we considered the relation...
The Canadian Journal of Psychiatry
August 1, 2002
Samantha R. Gross, Sean P. Barrett, John S. Shestowsky et al.
97 citations
Objective: This study investigates the drug consumption patterns of a sample of rave attendees in the city of Montreal, Quebec, and seeks to identify the prevalence of 3,4-methylendioxymethamphetamine (MDMA) and other drug use in this population. Method: We administered a self-report questionnaire to 210 respondents. For various licit and illicit substances, participants reported their age of...
The Canadian Journal of Psychiatry
November 1, 1999
Russell A Powell, Travis L Gee
Objective: To examine the possibility that hypnosis has significant iatrogenic effects on dissociative identity disorder (DID). Method: This paper reexamines previously published data that have been interpreted as indicating that hypnosis does not exert significant iatrogenic effects on DID. Results: The use of hypnosis is associated with differences in DID phenomenology and number of DID...
The Canadian Journal of Psychiatry
September 1, 1991
Douglas H. Frayn
15 citations
The dreams of anorexic patients' were recorded using a standardized sleep questionnaire concerning the perceptual qualities and affects remembered from their dreams. The anorexic subjects consistently had less frequent dream recall, fewer dreams in colour and fewer pleasurable themes than was noted in the normal controls. Anorexics frequently saw themselves in their dreams as having a distorted...
The Canadian Journal of Psychiatry
February 1, 1981
Alec Roy
7 citations
In a matched controlled study 37 chronic schizophrenics who had taken LSD preceding the onset of their illness were compared with schizophrenics who had not. There were no significant differences between the groups either on age at onset of symptoms or for age at first admission.
The Canadian Journal of Psychiatry
November 1, 1980
Angus S. Mcdonald
11 citations
This article reviews the major hallucinogenic fungi both for their historical as well as neurochemical import. Despite voluminous literature on them, relatively little study has focused on psilocybin related substances that could relate to forms of psychotic illness. Some metabolic pathways are reviewed which illustrate the need for more study of indole compounds such as baeocystin.