Accurate and Interpretable Prediction of Antidepressant Treatment Response from Receptor-informed Neuroimaging
bioRxiv (Cold Spring Harbor Laboratory) Hanna M. Tolle, Andrea I. Luppi, Timothy Lawn et al. 1 citation preprint
Conventional antidepressants show moderate efficacy in treating major depressive disorder. Psychedelic-assisted therapy holds promise, yet individual responses vary, underscoring the need for predictive tools to guide treatment selection. Here, we present graphTRIP (graph-based Treatment Response Interpretability and Prediction) – a geometric deep learning architecture that enables three...
DOI: 10.1101/2025.07.02.662710 (opens in new tab)
Psychedelic therapy
Depression treatment
Antidepressant therapy
Mdd treatment
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