Journal of American College Health
May 1, 1994
Michael J. Cuomo, Paul G. Dyment, Victoria M. Gammino
82 citations
We conducted a random survey of illicit drug use by undergraduate students at a private southern university in 1990 and compared the results with results from a similar 1986 survey of that college's student population. During the 4 years since the first study, the prevalence of cocaine use declined from 39% to 21%, and use of traditional amphetamines declined from 22% to 12%. No significant...
Psychiatric Annals
March 1, 1994
Robert L. Dupont, Karl Verebey
1 citation
LSD and Ecstasy and other hallucinogenic drugs (especially psilocybin mescaline) are in an anomalous position as frequently abused, widely available illicit drugs that are rarely identified in drug tests.
Archives of General Psychiatry
February 1, 1994
Ruck J. Strassman
454 citations
BACKGROUND: Validation of animal models of hallucinogenic drugs' subjective effects requires human data. Previous human studies used varied groups of subjects and assessment methods. Rating scales for hallucinogen effects emphasized psychodynamic principles or the drugs' dysphoric properties. We describe the subjective effects of graded doses of N,N-dimethyltryptamine (DMT), an endogenous...
Addiction
October 1, 1993
Henry David Abraham, Andrew M. Aldridge
140 citations
Abstract The continued endemic use of hallucinogenic drugs, and of LSD in particular, raises concern regarding their short and long term adverse consequences. The epidemiology of LSD abuse is reviewed suggesting an increase in LSD use among the young as the prevalence rates for other substances continues to fall. Evidence supports the association of LSD use with panic reactions, prolonged...
British Journal of Addiction
February 1, 1992
Christopher D Smith, Don Nutbeam
45 citations
Abstract As part of a larger survey of health‐related behaviours, 2239 15–16‐year‐olds in Wales provided information on their use of eight different types of drugs. Key findings indicate that just over a fifth of this age group report to having tried drugs at some time, while a tenth say they have done so within the past month. The most frequently reported substances were marijuana, solvents...
Karstenia
1992
Harri Nyberg
28 citations
NYBERG, H.1992: Religious use of hallucinogenic fungi: A comparison between Siberian and Mesoamerican cultures.-Karstenia32:71-80.The religious uses of hallucinogenic mushrooms in northern Eurasian and Mesoamerican cultures are compared.In northern Eurasia, some shamanistic cultures have used the Fly Agaric (Amanita muscaria (L.) Pers.);Mesoamericans, mainly mushrooms of the genus Psilocybe...
Planta Medica
June 1, 1989
Jochen Gartz
13 citations
Mycelial cultures of PSILOCYBE CUBENSIS, with the ability to form psilocybin and psilocin DE-NOVO, also hydroxylated and methylated fed tryptamine to give psilocin in up to 3.3% dry mass of the obtained fruit bodies. By using HPLC and TLC, it was found that these mushrooms contain only a small amount of psilocybin (0.01-0.2% dry mass). The values of psilocin are the highest described in any...
Journal of Psychoactive Drugs
1989
Gary Bravo, Charles S. Grob
38 citations
This article reviews the role of psychedelic drugs as potential tools for psychiatric research and practice. The decline in the utilization of these substances is linked to social reactions, which led to psychedelics being scheduled as controlled substances and consequently unavailable for human research. Three different paradigms for the use of psychedelics in psychiatry are reviewed: the...
European Journal of Pharmacology
1989
James B. Appel, Patrick M. Callahan
34 citations
In order to further evaluate the extent to which particular 5-HT receptor subtypes (5-HT1, 5-HT2) might be involved in the behavioral effects of hallucinogenic drugs, rats were trained to discriminate mescaline (10 mg/kg i.p.) from saline and were given substitution (generalization) and combination (antagonism) tests with putatively selective serotonergic and related neuroactive compounds. The...
Pharmacology, Biochemistry, and Behavior
1989
Janis T. Eells, Douglas M. Wilkison
10 citations
The effects of mescaline and LSD on the flash-evoked cortical potential (FEP) were determined in unrestrained rats with chronically-implanted electrodes. Systemic administration of mescaline or LSD significantly attenuated the primary component of the FEP at three stimulus intensities with the greatest effect observed 60-90 minutes following drug administration. The magnitude and specificity of...