British Journal of Pharmacology
March 1, 1974
Philip Bradley, Ian Briggs
54 citations
The actions of 5‐methoxytryptamine (5‐MeOT), N,N ‐dimethyltryptamine (DMT), 5‐hydroxy‐ N,N ‐dimethyltryptamine (bufotenine, 5‐HODMT) and 5‐methoxy‐ N,N ‐dimethyltryptamine (5‐MeODMT), and their interactions with 5‐hydroxytryptamine (5‐HT), acetylcholine, (–)‐noradrenaline, and glutamate were studied by microiontophoresis on single neurones in the brain stem of rats anaesthetized with urethane...
Crime & Delinquency
July 1, 1972
D F Duncan
1 citation
Psychedelic drugs have been used for individual psychotherapy in prison settings. This paper outlines two studies that explore the use of psychedelic drugs in correction. In 1961 Timothy Leary and Walter Houston Clark administered psilocybin to thirty-three prisoners at the Massachusetts Correctional Insti tution. This program seemed to have positive effects on the inmate-subjects. William H....
International Journal of Clinical and Experimental Hypnosis
1972
David Whitman van Nuys
4 citations
Abstract 47 undergraduate male volunteers were asked 2 questions relating to their use of marijuana and/or psychedelic drugs (e.g., LSD, mescaline, psilocybin) and were administered the Harvard Group Scale of Hypnotic Susceptibility, Form A (HGSHS:A). The HGSHS:A scores of Ss who had, at some time, taken any of these drugs averaged 2 points higher than scores of Ss who had not. Further research...
Pharmacology
1972
Wojciech Kostowski, W Rewerski, T Piechocki
28 citations
The action of JB-336, psilocybin, ibogaine and bufotenine on the aggressiveness os isolated mice, as well as the muricide reaction of rats, was investigated. All drugs evoked a substantial decrease in aggressiveness, but this effect was dependent on isolation time, time after injection and the type of test used.
Archives of General Psychiatry
1971
Solomon H. Snyder
30 citations
DOET (2,5-dimethoxy-4-ethylamphetamine) is a new psychotropic agent which chemically resembles mescaline and amphetamine. It is essentially the ethyl homologue of DOM (2,5-dimethoxy-4-methylamphetamine), a psychotomimetic drug widely used by hippie populations and designated "STP." DOET was administered to normal male subjects in doses ranging from 0.75 to 4 mg and contrasted with effects of a...
Journal of Pharmacy and Pharmacology
November 1, 1970
K. Genest, Lorna J. Lowry
Abstract Microcrystallopic tests for LSD, NN-diethyltryptamine, NN-dimethyltryptamine, bufotenine, psilocin, psilocybin and STP are described. The tests are recommended in conjunction with other analytical techniques if applied for the forensic identification of hallucingens.
JAMA
June 15, 1970
W. N. Pahnke
41 citations
The history of research with psychedelic drugs has produced a variety of methods for their use and conflicting claims about results. First came the wave of excitement among experimentalists in the 1950s when it was claimed that lysergic acid diethylamide (LSD) could produce a model psychosis which might be useful in understanding schizophrenia. While this promise was fading, enthusiastic...
American Journal of Psychiatry
October 1, 1969
Mardi J. Horowitz
125 citations
Flashbacks are returns of imagery for extended periods after the immediate effect of hallucinogens has worn off. The most symptomatic form is recurrent intrusions of the same frightening image into awareness, without volitional control. The author compares flashbacks with other clinical phenomena; he believes that psychotherapy is helpful, especially if there is a focus on the traumatic and...
British Journal of Pharmacology
February 1, 1969
Michael F. Sugrue
40 citations
LSD‐25, psilocybin and JB‐329 reduced the noradrenaline content of the rat hypothalamus. All three drugs affected the acquisition of a conditioned avoidance response, LSD‐25 and psilocybin retarding and JB‐329 enhancing the acquisition. With the exception of JB‐329, doses affecting the acquisition of a conditioned avoidance response were lower than those required to decide hypothalamic...
American Journal of Psychiatry
September 1, 1968
Solomon H. Snyder, Louis A. Faillace, Herbert Weingartner
77 citations
DOM, a hallucinogen related to mescaline and amphetamine and designated "STP" by hippies, along with DOET, the ethyl homologue of DOM, were given in small doses to normal subjects in a double-blind study. Both drugs increased self-awareness and produced mild euphoria but no hallucinogenic or psychotomimetic effects. The two drugs "freed up" subjects' word associations without impairing memory...