7 papers in the library · 432 citations · publishing 1982-2007
Annals of Clinical Psychiatry 2007 Rif S El-Mallakh, Henry David Abraham 17 citations
BACKGROUND: 3,4-Methylenedioxymethamphetamine (MDMA or Ecstasy) is a synthetic amphetamine analogue that is recreationally used to obtain a psychological effect of enhanced affiliative emotional response. Its use in Western countries appears to be increasing, particularly among young individuals. METHODS: Pertinent basic and clinical literature is critically reviewed. RESULTS: A significant...
Journal of Clinical Psychopharmacology June 1, 1996 Henry David Abraham, Anitra Mamen 50 citations
Risperidone, a novel antipsychotic agent, is an antagonist of postsynaptic serotonin-2 and dopamine D2 receptors. In certain individuals, the hallucinogenic drug lysergic acid diethylamide (LSD) is associated with apparently lifelong continuous visual disturbances, characterized in DSM-IV as hallucinogen-persisting perception disorder (HPPD). Because the hallucinogenic mechanism of LSD is known...
Addiction October 1, 1993 Henry David Abraham, Andrew M. Aldridge 140 citations
Abstract The continued endemic use of hallucinogenic drugs, and of LSD in particular, raises concern regarding their short and long term adverse consequences. The epidemiology of LSD abuse is reviewed suggesting an increase in LSD use among the young as the prevalence rates for other substances continues to fall. Evidence supports the association of LSD use with panic reactions, prolonged...
Archives of General Psychiatry June 1, 1984 Henry David Abraham 6 citations
In Reply.— Dr Hoffman's suggestion that one may find many of the visual disturbances that were described in my article1 in non-LSD—using persons is well taken. The diagnosis of the LSD flashback syndrome, like that of epilepsy, is primarily made by carefully obtaining a history. But before drawing such a conclusion, the clinician has the responsibility of excluding the possibility of...
Archives of General Psychiatry August 1, 1983 Henry David Abraham 172 citations
One hundred twenty-three persons with a history of LSD use were studied for the presence of the LSD flashback phenomenon and compared with 40 control subjects. A syndrome emerged that included ten distance visual disturbances. It had lasted for five years in half of the population, was treatable with benzodiazepines, exacerbated by phenothiazines, and precipitated by 19 different stimuli, most...
American Journal of Psychiatry April 1, 1983 Henry David Abraham 7 citations
The serotonin precursor L-5-hydroxytryptophan reversed the symptoms of a 23-year-old man suffering from LSD-induced psychosis who participated in a randomized, double-blind crossover study of the drug and a placebo. This finding is compatible with the speculation that some LSD-induced psychotic disorders may be caused by a relative deficiency of CNS serotonin.
The British Journal of Psychiatry May 1, 1982 Henry David Abraham 40 citations
Summary Forty-six users of the hallucinogen lysergic acid diethylamide were compared with 31 controls on a test of colour discrimination an average of two years after their last exposure to the drug. Controls performed better than users, and LSD users without flashbacks performed better than users with flashbacks. An analysis of variance between the three groups was significant at P <0.001....