Involvement of 5-HT receptor subtypes in the discriminative stimulus properties of mescaline
European Journal of Pharmacology 1989 James B. Appel, Patrick M. Callahan 34 citations
In order to further evaluate the extent to which particular 5-HT receptor subtypes (5-HT1, 5-HT2) might be involved in the behavioral effects of hallucinogenic drugs, rats were trained to discriminate mescaline (10 mg/kg i.p.) from saline and were given substitution (generalization) and combination (antagonism) tests with putatively selective serotonergic and related neuroactive compounds. The...