The generation of three-dimensional cerebral organoids from human-induced pluripotent stem cells (hPSC) has facilitated the investigation of mechanisms underlying several neuropsychiatric disorders, including stress-related disorders, namely major depressive disorder and post-traumatic stress disorder. Generating hPSC-derived neurons, cerebral organoids, and even assembloids (or multi-organoid...
Creativity is considered one of the skills crucial for 21 Century to face the challenges proposed by the 2030 education agenda (Frey & Osborne 2013; OECD, 2018, Reimers & Chung 2019). In our reading, active methodologies such as project-based learning and design thinking are often seen as fundamental in favoring creativity together oriented towards individual, social, and planetary well-being...
In this view, we address the problem of consciousness, and although we focus on its human presentation, we note that the phenomenon is present in numerous nonhuman species and use findings from a variety of animal studies to explain our hypothesis for how consciousness is made. Consciousness occurs when mind contents, such as perceptions and thoughts, are spontaneously identified as belonging...
Abstract This chapter is about experiments that aim to isolate the neural basis of conscious perception, but in line with the methodology discussed in Chapter 1, I am putting the issues of consciousness to one side, focusing on the neural basis of perception itself as contrasted with the neural basis of perceptual judgment. The chapter discusses the “no-report” paradigm not from the point of...
Time perception is closely related to spatial and bodily perception, yet little is known about how this interrelationship is impacted by meditation and biological sex. To examine this, we studied the effects of a stepwise application of three meditation techniques, from focused attention, to open monitoring to non-dual meditation, encompassed in the Place of Pre-Existence technique (PPEt) on...
ABSTRACT This paper discusses the relevance and experience of Pure Consciousness through a technique called Transcendental Meditation (TM). It posits the idea that this technique of meditation can prove to be a useful spiritual tool during the current pandemic and talks about its effects on education, mental health, as well as physical health through a review of scientific studies on TM. It...
Dreams are still an enigma of human cognition, studied extensively in psychoanalysis and neuroscience. According to the Freudian dream theory and Solms' modifications of the unconscious derived from it, the fundamental task of meeting our emotional needs is guided by the principle of homeostasis. Our innate value system generates conscious feelings of pleasure and unpleasure, resulting in the...
Psychedelics alter consciousness and may have potential for drug development. As psychedelics are likely therapeutically active, it is important to study their effects and mechanisms using preclinical models. Here, we examined the effects of phenylalkylamine and indoleamine psychedelics on locomotor activity and exploratory behaviour using the mouse Behavioural Pattern Monitor (BPM). DOM,...
BackgroundPromoting reflection about death may support better living, and how to carry out death education is an important issue to be addressed across the world. The purpose of the current study was to explore the attitude of heart transplant recipients toward death and their inner real experience to provide information for the development of death education strategies.MethodsA...
Human experience is imbued by the sense of being an embodied agent. The investigation of such basic self-consciousness has been hampered by the difficulty of comprehensively modulating it in the laboratory while reliably capturing ensuing subjective changes. The present preregistered study fills this gap by combining advanced meditative states with principled phenomenological interviews:...