Ethical Implications in Making Use of Human Cerebral Organoids for Investigating Stress—Related Mechanisms and Disorders
Cambridge Quarterly of Healthcare Ethics February 17, 2023 Katherine C. Bassil, Dorothee Horstkötter 38 citations
The generation of three-dimensional cerebral organoids from human-induced pluripotent stem cells (hPSC) has facilitated the investigation of mechanisms underlying several neuropsychiatric disorders, including stress-related disorders, namely major depressive disorder and post-traumatic stress disorder. Generating hPSC-derived neurons, cerebral organoids, and even assembloids (or multi-organoid...