Psychedelics are mainly from the class of psychoactive substances whose action is to produce changes in the perception, mood, cognitive behavior, and processes of a person. This psychedelic drug creates an alteration in a person’s thinking, sense of time, and emotions. Hallucinations can be a main cause for people who take psychedelics. Mainly, these psychedelic drugs have been used since...
Journal of Natural ProductsMarch 22, 2024Lucas Apolinário Chibli, Bruna Ribeiro de Lima, Ariadne Magalhães Carneiro et al.4 citations
The fact that alkaloids are bases has been the most explored chemical feature of their extraction and purification procedures. The main drawback of these procedures is that they employ undesirable chemicals, with HCl and CH2Cl2 probably being the most commonly employed chemicals in their subsequent steps. This work tested the hypothesis that advantages in recovery efficiency support this common...
Altered states of consciousness (ASCs) are surprisingly hard to define and to measure. Neither ‘subjective’ methods (like verbal reports) nor ‘objective’ measures (such as how the state is induced, or physiological and behavioural criteria) are entirely satisfactory. Attempts to map ASCs are reviewed, including two- or three-dimensional maps such as Tart&s;s and Laureys’, and Hobson&s;s AIM...
Psychedelics, such as psilocybin, mescaline and lysergic acid diethylamide (LSD), are psychoactive substances that induce alterations in cognition, perception and sensory processing. Studies in rodent models and healthy human volunteers highlight the serotonin 5-HT2A receptor’s pivotal role in mediating hallucinogenic effects. More recent findings indicate that psychedelics induce lasting...
The purpose of this article is to study the 'sacred' plants, diverse from those exclusively medicinal but with an unquestionable ethnobotanical value because, added to their healing properties, they develop mystical experiences and altered states of consciousness analogous to the ecstatic trance. _Psychoactive_ plants have played an important role in medicine, religion, _ritual_ life, and...
AbstractPeter Sjöstedt-Hughes attempts to help us understand psychedelic experience via the ideas of Aldous Huxley and Henri Bergson. More specifically, he attempts ‘to rectify and fortify’ Bergson’s metaphysics as it is represented in Aldous Huxley’s The Doors of Perception, a book about the use and experience of mescaline. In it, Huxley employs two Bergsonian concepts: that of the ‘reducing...
The use of psychedelic substances has intrigued, benefited, and challenged humanity for millennia. These substances, found regularly in nature, are known to induce non-ordinary states of consciousness. They provide heightened sensory, emotional and cognitive experiences, which include augmented visual imagery, changes in thought, mood, and awareness, perception of space-time and reality and, in...
In psychedelic therapy, the importance of set and setting is a fundamental but under-researched assumption. The aim of this study is to correlate variables of set (psychedelic use motivation) and setting (psychedelic use location and type of companion) with psychopathology, wellbeing and personality variables. A sample of 1022 participants of the Spanish-speaking population was collected...
Abstract Mystical-like states of consciousness may arise through means such as psychedelic substances, but may also occur unexpectedly during near-death experiences (NDEs). So far, research studies comparing experiences induced by serotonergic psychedelics and NDEs, along with their enduring effects, have employed between-subject designs, limiting direct comparisons. We present results from an...
Psychedelics are classical hallucinogen drugs that induce a marked altered state of consciousness. In recent years, there has been renewed attention to the possible use of classical psychedelics for the treatment of certain mental health disorders. However, further investigation to better understand their biological effects in humans, their mechanism of action, and their metabolism in humans is...