UNC Libraries
June 7, 2024
Kami Kim, Tao Che, Ouliana Panova et al.
Hallucinogens like lysergic acid diethylamide (LSD), psilocybin, and substituted N-benzyl phenylalkylamines are widely used recreationally with psilocybin being considered as a therapeutic for many neuropsychiatric disorders including depression, anxiety, and substance abuse. How psychedelics mediate their actions—both therapeutic and hallucinogenic—are not understood, although activation of...
Psychiatria
June 5, 2024
Anna Stankiewicz, Jan Szewczyk, Julia Truszkowska et al.
1 citation
Drug therapies for many psychiatric conditions do not meet patients’ expectations. New agents are being sought to treat depression and anxiety disorders, among others. Scientific interest in psychoactive substances has increased over the past few decades. Recent studies provide evidence that psychedelics may find use in the treatment of a range of mental disorders. This paper describes new...
Oxford Handbook of Addiction Medicine
June 1, 2024
Abstract Chapter 16 of Addiction Medicine covers hallucinogens, dissociative drugs, and empathogens. Hallucinogens, also termed psychedelics, are a large and diverse group of substances, some of which occur in fungi and plants and some which are chemically synthesized. Some have psychostimulant properties as well. They include psilocybin, mescaline, dimethyltryptamine (DMT), ayahuasca, lysergic...
European Journal of Neuroscience
May 21, 2024
Nur Damla Korkmaz, Ugur Cikrikcili, Merve Akan et al.
19 citations
Abstract Psychoactive substances obtained from botanicals have been applied for a wide variety of purposes in the rituals of different cultures for thousands of years. Classical psychedelics from N,N′‐dimethyltryptamine, psilocybin, mescaline and various lysergamides cause specific alterations in perception, emotion and cognition by acting through serotonin 5‐HT 2A receptor activation. Lysergic...
Journal of Psychedelic Studies
May 10, 2024
Jarrett Robert Rose
3 citations
Revival, resurgence, renaissance-call it what you will, we are bearing witness to a second age of psychedelia in the West.It is well understood that the fruits borne of today's great scientific, therapeutic, and cultural advancements owe much to the seeds planted by the giants of the past.Yet when that past is discussed, the conversation is often dominated by the influence of only a select few...
Research Posters
May 2, 2024
David F Lo, Hasan Zia, Adarsh Thakur et al.
1 citation
This poster explores the effects of psychedelic microdosing on mental health conditions. Roughly 5.5 million individuals in the U.S. utilize psychedelics to treat their mental health issues. The primary substances used for microdosing currently include LSD and psilocybin, but mescaline, DMT, and amphetamines are used less commonly. This systematic review included 16 unique articles. The types...
European Journal of Arts Humanities and Social Sciences
May 1, 2024
Nicholas A. Kerna, Kevin D. Pruitt, N.d. Victor Carsrud et al.
Entheogens, a class of psychoactive substances with profound cultural and religious significance, have been utilized for centuries across diverse traditions for healing, spiritual exploration, and communication with the divine. Their historical usage spans continents, from the pre-Columbian Americas to traditional African practices and Ayurvedic medicine in India. While entheogens offer...
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
May 1, 2024
Mark A. Geyer
30 citations
Classical serotonergic psychedelics such as lysergic acid diethylamide or the naturally occurring compounds psilocybin and mescaline produce profound changes in mood, thought, intuition, sensory perception, the experience of time and space, and even the experience of self. Research examining psychedelic compounds has had a complex and turbulent evolution. Many cultures throughout the world have...
Dermatitis
April 18, 2024
Syed Minhaj Rahman, Yousef Salem, Aamir Hussain
4 citations
Although psychedelic and hallucinogenic substances have gained popularity for therapeutic use, their dermatologic adverse effects are poorly characterized. This review characterizes the cutaneous reactions associated with psychedelic and hallucinogenic drugs. A review of PubMed and Scopus was conducted from the inception of databases to August 31, 2023. Search terms included drug names and...
European Psychiatry
April 1, 2024
J. S. Seo
Introduction Recently, the pros and cons have been debating in Korea even before the approval of use of medical marijuana with very strict limitations. And the next controversial topic is psychedelics. In 1890, when mescaline was first isolated from peyote cactus, clinical researches began, but due to its harmful effects, it was thereafter legally prohibited in 1970 in USA. However, a...