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Journal of Psychoactive Drugs 1976 Paul Pascarosa, Sanford Futterman 23 citations
(1976). Ethnopsychedelic Therapy for Alcoholics: Observations In the Peyote Ritual of the Native American Church. Journal of Psychedelic Drugs: Vol. 8, Innovative Approached to Drug Abuse Treatment, pp. 215-221.
Psychopharmacology 1976 Hubert Korr 5 citations
Autoradiographs of the brain of the marmoset, Callithrix jacchus, show a strong labeling of the hippocampus and the N. amygdalae 18 h after injection of 3H-mescaline. A similar characteristic autoradiographic pattern was previously found in the mouse brain, too.
Psychopharmacology 1976 Sergio Solbes Ferri, A. Santagostino, Pier Carlo Braga 4 citations
Tolerance and cross tolerance to the antinociceptive effect of equipotent doses of morphine (10 mug/kg) and mescaline (100 mug/kg) are shown in the rabbit after their repeated intracerebroventricular administration. The recording of the electrical activity of different brain areas indicates that a partial tolerance also develops to the EEG effects in animals undergoing chronic treatment with...
Psychopharmacology 1976 David M. Stoff, Richard Jed Wyatt, J. Christian Gillin 6 citations
Acute parachlorophenylalanine (pCPA) pretreatment (150 mg/kg, i.p., 24 h beforehand) potentiated facilitatory effects of mescaline (39.6 mg/kg i.p.) on shuttlebox escape/avoidance in hooded rats, tested in two different situations: 1. during aquisition of avoidance behavior (Experiment 1); and 2. in stable pretrained poor avoiders (Experiment 2). pCPA alone did not influence avoidance behavior...
Psychopharmacology 1976 Sergio Solbes Ferri, A. Santagostino, P. C. Braga 6 citations
Some effects of intraventricular injection of mescaline are examined in conscious rabbits. By means of electrical stimulation of the tooth pulp it is shown that an acute treatment with 70, 100, 150 mug/kg of mescaline elicits analgesia, the intensity of which is dose-dependent: with daily administration of 100 mug/kg for 5 days a complete tolerance develops to the antinociceptive effect. A...
Journal of Pharmaceutical Sciences December 1, 1975 Robert J. Wolters, Ansuman Bej, N. S. Tanner 5 citations
The synthesis of methyl-2-(3,4,5-trimethoxyphenyl)-2-(2-piperidyl) acetate is described. In addition, preliminary pharmacological data comparing the compound with mescaline are given.
JAMA October 20, 1975 David Dorrance 20 citations
Fify-seven Huichol Indians with a lifelong individual history and a 1,600-year cultural tradition of ingestion of peyote, a mescaline-containing cactus possessing hallucinogenic properties, were compared with 50 Huichol Indian controls and ten laboratory controls for effects on lymphocyte chromosomes. The frequency of abnormalities in the experimental and control groups did not differ...
JAMA October 20, 1975 A. D. Bloom 1 citation
Given the controversy of the late 1960s and early 1970s over the possible induction of chromosomal damage by psycho-active agents like LSD and marihuana, the peyote study of Teplitz et al (p 299), is reassuring. It is, first of all, comforting to know that in vivo studies of agents that are possible chromosomal mutagens can produce, when properly designed and executed, clear-cut results....
JAMA October 20, 1975 Arthur D. Bloom 4 citations
Given the controversy of the late 1960s and early 1970s over the possible induction of chromosomal damage by psycho-active agents like LSD and marihuana, the peyote study of Teplitz et al (p 299), is reassuring. It is, first of all, comforting to know that in vivo studies of agents that are possible chromosomal mutagens can produce, when properly designed and executed, clear-cut results....
Pharmacology, Biochemistry, and Behavior September 1, 1975 Brooks Carder, Robert J. Sbordone 8 citations
Rats were exposed to a series of targets in a shock induced aggression situation. Control rats fought most with moving targets, such as another normal rat, and did not attack immobile targets, such as a dead rat or a rat model. Rats treated with 15 mg mescaline/kg showed a similar pattern of target control though they bit frequently while controls did not bite. Rats treated with 50 mg/kg...