methaodos.revista de ciencias sociales
May 10, 2017
Lizett Pérez Castro, Omar Antonio Ponce Carrillo, Ricardo Antonio Flores Reyes
2 citations
“The revolution of man is the revolution of his mind”. It implies the possibility of thinking beyond himself, to understand his raison d'être, as a criticism of his own material activity, that locks him out in a perpetual animal state. As the German philosopher Georg Simmel implies in his philosophical work, man is the only animal that refines itself by looking beyond himself. As we cling to...
Current Topics in Behavioral Neurosciences
2017
Juan F López-Giménez, Javier González-Maeso
302 citations
The neuropsychological effects of naturally occurring psychoactive chemicals have been recognized for millennia. Hallucinogens, which include naturally occurring chemicals such as mescaline and psilocybin, as well as synthetic compounds, such as lysergic acid diethylamide (LSD), induce profound alterations of human consciousness, emotion, and cognition. The discovery of the hallucinogenic...
Frontiers in Human Neuroscience
December 22, 2016
Philipp Sterzer, Aaron Mishara, Martin Voss et al.
78 citations
Current theories in the framework of hierarchical predictive coding propose that positive symptoms of schizophrenia, such as delusions and hallucinations, arise from an alteration in Bayesian inference, the term inference referring to a process by which learned predictions are used to infer probable causes of sensory data. However, for one particularly striking and frequent symptom of...
Arquivos de Neuro-Psiquiatria
December 1, 2016
Hélio A G Teive, Francisco M B Germiniani, Pedro A Kowacs et al.
Three world-famous neurologists, Charcot and Mitchell, in the 19th century, and Lees, in this century, all of whom had great scientific curiosity, experimented with the psychoactive drugs hashish, mescal and yagé, respectively, in an attempt to increase their knowledge of neurological diseases and how the brain works.
Neuroscience & Biobehavioral Reviews
December 2016
Rafael G. Dos Santos, Flávia L. Osório, José Alexandre S. Crippa et al.
Serotonergic hallucinogens produce alterations of perceptions, mood, and cognition, and have anxiolytic, antidepressant, and antiaddictive properties. These drugs act as agonists of frontocortical 5-HT2A receptors, but the neural basis of their effects are not well understood. Thus, we conducted a systematic review of neuroimaging studies analyzing the effects of serotonergic hallucinogens in...
Current Psychiatry Reviews
August 10, 2016
Cornel N. Stanciu, Thomas M. Penders
3 citations
Hallucinogen Persistent Perception Disorder (HPPD) is considered an “uncommon” disorder described in association with use of hallucinogens such as LSD, mescaline and psilocybin. Despite multiple mentions of persistence of visual disturbances reported by users on online forums, clinicians may not be aware of this complication. There have been few descriptions of HPPD in association with use of...
Zebrafish
March 22, 2016
Evan J. Kyzar, Allan V. Kalueff
29 citations
After decades of sociopolitical obstacles, the field of psychiatry is experiencing a revived interest in the use of hallucinogenic agents to treat brain disorders. Along with the use of ketamine for depression, recent pilot studies have highlighted the efficacy of classic serotonergic hallucinogens, such as lysergic acid diethylamide and psilocybin, in treating addiction, post-traumatic stress...
European Psychiatry
March 1, 2016
Laura Orsolini, Alessandro Valchera, Duccio Papanti et al.
3 citations
Introduction Hallucinogen Persisting Perception Disorder (HPPD) is a syndrome characterized by prolonged or reoccurring perceptual symptoms, reminiscent of acute hallucinogen effects. HPPD was associated with a broader range of LSD (lysergic acid diethylamide)-like substances, including cannabis, MDMA (methylenedioxymethamphetamine), psilocybin, mescaline and other psychostimulants....
Psychological Medicine
February 5, 2016
Robin Carhart-Harris, Mendel Kaelen, Mark Bolstridge et al.
301 citations
Background Lysergic acid diethylamide (LSD) is a potent serotonergic hallucinogen or psychedelic that modulates consciousness in a marked and novel way. This study sought to examine the acute and mid-term psychological effects of LSD in a controlled study. Method A total of 20 healthy volunteers participated in this within-subjects study. Participants received LSD (75 µ g, intravenously) on one...
Journal of medical biography
February 1, 2016
Robert M. Kaplan
9 citations
This article describes the life and work of the psychiatrist Humphry Osmond who pursued a radical path as a psychiatrist while he remained within the establishment. To the public mind however, he is best known as the man who introduced Aldous Huxley to mescaline and coined the iconic word psychedelic. From an early stage of his career, Henry Osmond embraced new ideas to break the nexus in...