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The Biochemist

ISSN 0954-982X

5 papers in the library · 6 citations · publishing 2007-2024

Papers

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Could the medicalization of psychedelics lead to the next generation of antidepressants?

The Biochemist March 28, 2024 Peter J. Duggan, S. Walker 1 citation

A major part of the counterculture that emerged in western societies in the 1960s centred around the use of mind-altering psychedelic drugs such as lysergic acid diethylamide (LSD). Humans had, however, been consuming hallucinogenic substances since prehistoric times and often incorporated them into their religious rituals. Concerns over the effects of potent psychedelics like LSD led to them...

Psychedelics: reconnecting the brain to heal the mind

The Biochemist March 25, 2024 David Nutt 3 citations

Natural psychedelics such as magic mushrooms have a long history of human use of at least 7000 years. Their use underwent a resurgence in the 1950/1960s following the synthesis of LSD as a psychedelic and its use as a medicine with powerful therapeutic benefits. But because non-medical use led to massive cultural changes especially in young people, all psychedelics were banned globally in the...

Scanning the new frontier of mental health: psychedelic brain imaging

The Biochemist March 14, 2024 Natalie Ertl, Matthew B. Wall

The use of psychoactive substances for ritual, spiritual and medicinal purposes stretches back into prehistory and has been a common feature of many diverse cultures and societies globally. Psychedelics, with their unique ability to amplify feelings of connectedness and openness, may have also served as tools for promoting tribal cohesion and trust in ancient cultures. Psychedelic is a broad...

Psychedelics for mental health: a biochemical perspective

The Biochemist January 19, 2024 Javier González-Maeso

Psychedelics, such as psilocybin, mescaline and lysergic acid diethylamide (LSD), are psychoactive substances that induce alterations in cognition, perception and sensory processing. Studies in rodent models and healthy human volunteers highlight the serotonin 5-HT2A receptor’s pivotal role in mediating hallucinogenic effects. More recent findings indicate that psychedelics induce lasting...

Acid trip: The history of LSD -- the original psychedelic drug

The Biochemist April 1, 2007 Erika Dyck 2 citations

In April 1943, Dr Albert Hofmann, a Swiss biochemist, dissolved a few micrograms of a newlysynthesized drug, d-lysergic acid diethylamide (LSD), in a glass of water and drank it. Three-quarters of an hour later, he recorded a growing dizziness, some visual disturbances and a marked desire to laugh. After about an hour he asked his assistant to call a doctor and accompany him home from his...