Research into psychedelics’ clinical potential has corresponded to a growth in public interest and adult use. One common pathway to accessing psychedelics is through psychedelic retreats. While individual retreats have been characterized in the anthropological literature, no systematic evaluation of the psychedelic retreat industry exists. Assessing the characteristics of the psychedelic...
Abstract Introduction Research on psychedelic use and sleep satisfaction remains unclear despite increased use. This study examines the psychedelic use and sleep satisfaction among 18-to-35-year-olds enrolled in the Herbal Heart Study. Methods The exposure variables were lifetime self-reported use of any psychedelic (LSD, psilocybin, peyote, mescaline, ayahuasca/DMT) and psilocybin-alone. Sleep...
Psychedelic drugs, known for their perception-altering properties, are gaining popularity in the treatment of mental health and pain disorders. As exploratory studies demonstrate clinical efficacy with few adverse events, it is expected that more patients will ingest psychedelic drugs. For therapeutic reasons, as with any drug, anaesthesiologists must be aware of its physiological effects and...
This chapter explores the key differences between entheogens and synthetic psychedelics, focusing on their origins, cultural contexts, and effects on consciousness. Entheogens are naturally occurring substances, such as psilocybin, ayahuasca, and peyote, traditionally used by Indigenous cultures for spiritual and healing purposes. These substances are often consumed in ceremonial settings with...
Improved outcomes for substance use disorders have been described following non-clinical (“naturalistic”) psychedelic use. This exploratory study aimed to describe the naturalistic psychedelic experiences of people with substance use concerns and their reported needs and perceived utility of psychosocial support following naturalistic psychedelic use to integrate experiences and achieve...
Abstract Background and Hypothesis Visual hallucinations (VH) are a core symptom of both Lewy body diseases (LBDs; eg, Parkinson’s disease and dementia with Lewy bodies) and serotonergic psychedelics (SPs; eg, psilocybin and mescaline). While these conditions differ in etiology, overlapping phenomenology, and neural mechanisms suggest shared pathways. This review explores similarities and...
Introduction Persons with schizophrenia are currently excluded from psychedelic-assisted therapy due to concerns about psychedelic-induced acute or persistent psychotic symptoms. However, meta-analytic evidence of the precise risk for psychedelic-induced de novo and exacerbation of psychosis in people with pre-existing psychotic disorders is lacking. Objectives We conducted an overview of...
Archives of ToxicologyMarch 10, 2025Yiling Tang, Linhao Xu, Zhenshuo Guo et al.1 citation
New psychoactive substances (NPS) are substances that are not controlled by international drug control conventions but are abused and pose a threat to public health. Proscaline and methallylescaline are two phenylethylamines with psychoactive and stimulant effects and are also derivatives of the classic hallucinogen mescaline. However, limited toxicity information on proscaline and...
Abstract This chapter explores the ways in which Indigenous migrations at the turn of the century contributed to two intertribal movements that sparked cultural and spiritual revitalization and political mobilization in the early decades of the twentieth century: the Peyote Religion and the Society of American Indians. It aims to reconsider the ways in which these movements imagined and acted...
The subject of this study is the methodological approach used by Aldous Huxley to study religious experience and mystical experiences. The article pays special attention to the theoretical origins of this methodology, as well as the social and cultural context of its formation. The article examines how science, philosophy, and religion of that time contributed to the formulation of Aldous...