La presente entrevista con Kuahtli Vásquez, médico peyotero de ascendencia mexica, refiere,en primera instancia, las experiencias de aprendizaje del médico tradicional y su relacióncon el contexto político de los indígenas en el norte de México. Luego introduce a otromédico tradicional, esta vez del Putumayo, en busca de la medicina del yagé o ayahuasca,y lo que implica el encuentro entre...
BACKGROUND: Salvinorin-A is a terpene found in the leaves of the plant Salvia divinorum. When administered to humans, salvinorin-A induces an intense but short-lasting modified state of awareness, sharing features with those induced by the classical serotonin-2A receptor agonist psychedelics. However, unlike substances such as psilocybin or mescaline, salvinorin-A shows agonist activity at the...
Sir, Ms. Sufentanyl, a charming “China girl,” and Ms. Mescaline, the cute Mexican lady, were invited by Mr. Marijuana at a dinner in “Chinese restaurant” in an “angel dusty” evening. Ms. Mescaline felt “ecstatic” and “Echo de la pensee” and on the occasion she “DRESS”ed herself with “heavenly blue” frock and adorned her eyes with mascara of “belladonna.” Ms. Sufentanyl wore a necklace with...
N-2-methoxybenzyl-phenethylamines (NBOMe drugs) are newly used psychoactive substances with poorly defined pharmacological properties. The aim of the present study was to characterize the receptor binding profiles of a series of NBOMe drugs compared with their 2,5-dimethoxy-phenethylamine analogs (2C drugs) and lysergic acid diethylamide (LSD) in vitro. We investigated the binding affinities of...
Hendricks et al. (2015) found that having ever used any classic psychedelic substance—namely, dimethyltryptamine (DMT), ayahuasca, lysergic acid diethylamide (LSD), mescaline, peyote or San Pedro, or psilocybin—was associated with a significantly reduced likelihood of past month psychological distress (weighted OR = . 81 (. 72–. 91)), past year suicidal thinking (weighted OR = . 86 (. 78–....
Abstract While María Sabina has long been an iconic figure among drug enthusiasts and advocates for indigenous rights, her sometime collaborator Salvador Roquet remains largely unknown. This essay introduces the work of this iconoclastic psychiatrist and, in particular, his work with Sabina, highlighting their contributions to the world of psychedelic psychiatry and exploring the nature of...
Desde a metade da última década, em grandes cidades do Brasil, começou a se difundir o uso da secreção da perereca Phyllomedusa bicolor. Um pouco mais tarde, partir da segunda década deste século, tornou-se possível alcançar informações sobre tal difusão em cidades europeias e norte-americanas. Tradicionalmente usada como revigorante e estimulante para caça por grupos indígenas do sudoeste...
The serotonin (5-Hydroxytryptamine, 5-HT) 2A receptor represents one of the most striking examples where functional selectivity (or ligand-biased signaling) is transduced in distinct behaviours. This receptor is the primary target of psychedelic hallucinogens such as lysergic acid diethylamine, mescaline and psilocybin, which reproduce some of the core symptoms of schizophrenia and are often...
It's all Kind of Magic: The Young Ken Kesey, by Rick Dodgson, Madison, University of Wisconsin Press, 2013. 256 pp. $26.95 US (cloth). There are some useful biographies of Sixties counter-cultural icons like Hunter Thompson or Timothy Leary, but an insightful account of life and times of Ken Kesey was lacking. Rick Dodgson had filled gap by offering first academic biography of best-selling...
This article examines firewood in the context of the modern practice of the Big Moon Peyote Religion by the Osage Indian community of Osage County, in northeastern Oklahoma, U.S.A. The fire and its ritual maintenance is a major component of the all night ceremony of Peyotism. The selection and preparation of the wood used in the ritual fire incorporates botanical knowledge, ceremonial...