Journal of inorganic biochemistry
2023
Alessandra Carvalho, Barbara Marinho Barbosa, Jesica S Flores et al.
14 citations
Alzheimer's disease (AD) is related to the presence of extracellular aggregated amyloid-β peptide (Aβ), which binds copper(II) with high affinity in its N-terminal region. In this sense, two new 1-methylimidazole-containing N-acylhydrazonic metallophores, namely, X1TMP and X1Benz, were synthesized as hydrochlorides and characterized. The compound X1TMP contains the 3,4,5-trimethoxybenzoyl...
Middle Atlantic Review of Latin American Studies
December 23, 2022
Meghan Tierney
Many scholars assume that the ancient Nasca practiced a form of shamanism on the south coast of present-day Peru (c. 1–750 CE). Typically, the identification of entheogens and shaman figures as subject matter in the vast corpus of Nasca polychrome ceramics supports those claims; however, visual analysis of the vessel forms and images reveals further evidence of a deeper understanding of...
International Journal for the Psychology of Religion
December 5, 2022
Arne Bohn, Michiel H. H. Kiggen, Malin V. Uthaug et al.
10 citations
San Pedro, a mescaline containing cactus, has been used for thousands of years and is currently popular as a psychedelic substance in ceremonial retreats in Europe. The current research investigates the consciousness altering effects of San Pedro. Forty-two participants who joined ceremonial psychedelic retreats in the Netherlands were investigated with questionnaires probing 11 dimensions of...
Naunyn-Schmiedeberg's Archives of Pharmacology
November 1, 2022
Joachim Neumann, Karyna Azatsian, Christian Höhm et al.
7 citations
Abstract The use of recreational drugs like ephedrine, norephedrine, 3,4-methylenedioxymethamphetamine (MDMA), and mescaline can lead to intoxication and, at worst, to death. One reason for a fatal course of intoxication with these drugs might lie in cardiac arrhythmias. To the best of our knowledge, their inotropic effects have not yet been studied in isolated human cardiac preparations....
Archives of Psychiatry Research
October 20, 2022
Din Duraković, Ante Silić, Vjekoslav Peitl et al.
1 citation
The paper deals with a case report of a 41-year-old man who in search of the meaning of life in a so-called “shamanic ritual” drank tea made from the San Pedro cactus as well as paste made of the same plant. The hallucinations were post poned and started after 9.5 hours caracterised by a psychotic reaction with symptoms of catatonia. He was admitted to our Department of Psychiatry where he was...
Drug Testing and Analysis
October 17, 2022
Ryan Gallagher, Maddison G. Mclaughlin, Karen Blakey et al.
2 citations
Abstract N,N ‐Diformylmescaline, a novel analogue of mescaline, has recently been detected in Australia in two unrelated seizures. To confirm the identification, a three‐step synthesis from 3,4,5‐trimethoxyphenylacetic acid was devised. However, purification of the final product proved problematic with the compound prone to degradation in solution. Analysis of the compound by LC–MS indicated...
Neuropharmacology
October 14, 2022
Ian G Campbell, Ioanna A. Vamvakopoulou, Kelly A.d. Narine et al.
97 citations
The pharmacological mechanisms of mescaline are similar to those of other classical psychedelics, like psilocybin and lysergic acid diethylamide (LSD). Mescaline appears to be safe to consume, with most intoxications being mild and easily treatable. Improvement in mental well-being and its ability to overcome alcoholism render mescaline potentially beneficial in clinical settings. This article...
Letters in Applied NanoBioScience
September 17, 2022
3 citations
Medical hallucinogens have been important compounds of research interest in recent years. Computational chemistry methods like Density Functional Theory (DFT) calculations at BP86/Def2-TZVP level are carried out to get more insight into the structural preferences and mechanism of hallucinogens like psilocybin and mescaline derivatives at the molecular level. The molecular structure, reactivity,...
Perífrasis Revista de Literatura Teoría y Crítica
August 29, 2022
Matías di Benedetto
In this novel the presence of the San Pedro cactus shows not only the shaman’s therapeutic operations but also the way in which the ecstasy produced by its consumption is defined as a chemical and aesthetic procedure, with somatic-political repercussions and experimental aspirations from the point of view of its literary concreteness. In this way, the experimentation of the visions that is...
Cultura y Droga
July 20, 2022
Mauricio Genet Guzmán Chávez, José Noyola Cherpitel
El uso terapéutico del peyote ocupa un lugar destacado en los círculos y contextos rituales de curación en diferentes partes del territorio nacional mexicano. El objetivo en este artículo es evaluar desde un enfoque psiquiátrico y antropológico los beneficios terapéuticos entre miembros (hombres y mujeres) no indígenas de clase media, que lo consumen dentro del formato ritual de la Iglesia...