Emotion
December 12, 2011
Margaret E Kemeny, Carol Foltz, James F Cavanagh et al.
Contemplative practices are believed to alleviate psychological problems, cultivate prosocial behavior and promote self-awareness. In addition, psychological science has developed tools and models for understanding the mind and promoting well-being. Additional effort is needed to combine frameworks and techniques from these traditions to improve emotional experience and socioemotional behavior....
The International Journal of Neuropsychopharmacology
November 1, 2011
Giacomo Salvadore, Jan Willem van der Veen, Yan Zhang et al.
105 citations
Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of major depressive disorder (MDD). We used proton magnetic resonance spectroscopy (¹H-MRS) to investigate whether prefrontal levels of amino-acid neurotransmitters predict antidepressant response to a single intravenous infusion of the N-methyl-D-aspartate (NMDA) antagonist ketamine in MDD patients....
Journal of Consulting and Clinical Psychology
October 1, 2011
Bruce W Smith, J Alexis Ortiz, Laurie E Steffen et al.
Objective: This study investigated the association between mindfulness, other resilience resources, and several measures of health in 124 urban firefighters. Method: Participants completed health measures of posttraumatic stress disorder (PTSD) symptoms, depressive symptoms, physical symptoms, and alcohol problems and measures of resilience resources including mindfulness, optimism, personal...
Behavior Therapy
October 1, 2011
Willoughby B. Britton, Ben Shahar, Ohad Szepsenwol et al.
The high likelihood of recurrence in depression is linked to a progressive increase in emotional reactivity to stress (stress sensitization). Mindfulness-based therapies teach mindfulness skills designed to decrease emotional reactivity in the face of negative affect-producing stressors. The primary aim of the current study was to assess whether Mindfulness-Based Cognitive Therapy (MBCT) is...
Anesthesiology
October 1, 2011
Edgar Alfonso Romero-Sandoval
21 citations
Dartmouth Medical School, Dartmouth College, Lebanon, New Hampshire. edgar.a.romero-sandoval@dartmouth.eduA LARGE population of patients concomitantly experiences chronic pain and depression or symptoms of depression (52% in pain clinics, or 85% in chronic facial pain dental clinics, for example).1How these two syndromes coexist, interact, reinforce each other, and/or are maintained is poorly...
Anesthesiology
October 1, 2011
Jing Wang, Yossef Goffer, Duo Xu et al.
171 citations
BACKGROUND: Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with chronic pain and whether this antidepressant effect depends on its...
International Journal of Nursing Studies
September 29, 2011
Piyanee Klainin‐Yobas, Ma Aye Aye Cho, Debra Creedy
Objectives: Depression, a common mental health problem, is projected to be the second leading cause of disability for adults by year 2020. Mindfulness-based interventions (MFIs) have been integrated into therapeutic work on depression, but limited systematic reviews reported their efficacy on heterogeneous groups of mental disorders. This meta-analysis aimed to examine the efficacy of the MFIs...
臺灣精神醫學
September 1, 2011
Chun‐Yi Lee, Jung-Kwang Wen
Objective: A socio-cultural model of depression in Confucianism-oriented societies has the basic assumption that its psychopathology is determined by the disturbance of a harmonious relationship with others. We present a case study in the context of the socio-cultural background to address the relevant issues regarding mental health. Case Report: A 46-year-old housewife patient with major...
Pharmacopsychiatry
September 1, 2011
Milan Scheidegger, Anke Henning, Martin Walter et al.
Background: Ketamine is a potent NMDA receptor antagonist with rapid antidepressant properties at subanaesthetic doses. This multimodal imaging study reveals the effects of a subanaesthetic ketamine infusion on fMRI-BOLD responses during an emotional processing task and their relationship to glutamatergic metabolite concentrations in the pregenual anterior cingulate cortex (PACC) assessed by...
Pharmacopsychiatry
September 1, 2011
Simone Grimm, Milan Scheidegger, Anke Henning et al.
Ketamine is a potent glutamatergic NMDA receptor antagonist with rapid antidepressant properties, thus providing a valuable research tool for the investigation of the neurobiology of major depressive disorder (MDD). Increasing evidence underscores the role of glutamate dependent neuroplasticity and glutamatergic neurotransmission and metabolism in the pathophysiology of MDD. This multimodal...
Cognitive and Behavioral Practice
August 1, 2011
Stuart J. Eisendrath, M. Chartier, Maura Mclane
Major depressive disorder (MDD) is currently ranked the third leading cause of disability in the world. Treatment-Resistant Depression (TRD) causes the majority of MDD's disability. Strikingly, 50% of individuals with MDD will fail to remit with two adequate trials of antidepressant medications, thus qualifying as treatment resistant. Current pharmacological and psychotherapeutic treatment...
Journal of Consulting and Clinical Psychology
July 18, 2011
Nicole Geschwind, Frenk Peeters, Marjan Drukker et al.
440 citations
OBJECTIVE: To examine whether mindfulness-based cognitive therapy (MBCT) increases momentary positive emotions and the ability to make use of natural rewards in daily life. METHOD: Adults with a life-time history of depression and current residual depressive symptoms (mean age = 43.9 years, SD = 9.6; 75% female; all Caucasian) were randomized to MBCT (n = 64) or waitlist control (CONTROL; n =...
Cognitive Behaviour Therapy
June 28, 2011
Jason M. Lavender, Kim L Gratz, Matthew T Tull
Although researchers have examined the efficacy of acceptance- and mindfulness-based interventions in the treatment of eating disorders, few studies have explored the association between trait mindfulness and eating pathology. Therefore, the purpose of the current investigation was to examine the unique associations between multiple facets of mindfulness (acting with awareness, nonreactivity,...
Behavioural Brain Research
June 6, 2011
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Psychology and Psychotherapy Theory Research and Practice
June 2011
Johannes Michalak, Anne Hölz, Tobias Teismann
In mindfulness-based cognitive therapy (MBCT), it is proposed that training in mindfulness should reduce the tendency of formerly depressed patients to enter into ruminative thinking, thus reducing their risk of depressive relapse. However, data showing that rumination is associated with depressive relapse are lacking. In an uncontrolled study with 24 formerly depressed patients, rumination was...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
June 1, 2011
Lobna Ibrahim, Nancy Diazgranados, David A. Luckenbaugh et al.
Ketamine rapidly improves depressive symptoms in patients with treatment-resistant major depressive disorder (MDD) who do not respond to multiple standard antidepressants. However, it remains unknown whether ketamine is equally effective in patients with MDD who previously also did not respond to electroconvulsive therapy (ECT). This study compared 17 patients with treatment-resistant MDD who...
Complementary Therapies in Clinical Practice
May 25, 2011
Meditation for the management of adjustment disorder anxiety and depression.
Clinical Psychology Review
May 15, 2011
The effect of mindfulness-based cognitive therapy for prevention of relapse in recurrent major depressive disorder: a systematic review and meta-analysis.
The International Journal of Neuropsychopharmacology
May 5, 2011
Retracted
A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department.
Psychology and Psychotherapy Theory Research and Practice
April 13, 2011
Sandy Sachse, Saskia Keville, Janet Feigenbaum
Objectives: Mindfulness-based cognitive therapy (MBCT) was originally developed to prevent relapse in recurrent depression. More recently it has been applied to individuals at high risk of suicide or currently suffering with anxiety and depression. The aim of this study was to consider the feasibility of MBCT for individuals with a diagnosis of borderline personality disorder (BPD). Design: The...