Sleep-related out-of-body experiences (OBEs) occupy an ambiguous position between sleep paralysis and lucid dreaming. OBEs are often considered part of the vestibular-motor component of sleep paralysis, but they also share features with lucid dreaming, including vivid internally generated experience, heightened awareness, and perceived agency. Here, we examined whether the emotional composition...
This chapter proposes that self-transcendent experiences can be usefully understood through the distinction between the reflective and experiential self, originally articulated by William James and developed in contemporary philosophy and neuroscience. The reflective self involves conscious, narrative self-referential processing, while the experiential self refers to affective processing and...
The renewal of psychedelic medicine has garnered significant scientific interest, with large efforts dedicated to the understanding of the complex subjective experiences induced by these substances. The Altered States of Consciousness (ASC) questionnaire represents the most comprehensive instrument for measuring such experiences yet lacks a validated French translation despite its centrality to...
Background. Near-death experience (NDE) is an altered state of consciousness experienced at the moment of near death, which has a specific structure (which includes such elements as an out-of-body experience, a feeling of movement in a dark tunnel, a review of life, visions of bright light, other realities and meetings with the dead, and many others). The similarity of reports on the NDE of...
Background Breathwork that increases ventilatory rate or depth represents an accessible non-pharmacological modality for potentially inducing altered states of consciousness (ASCs). Despite gaining traction as a potential therapeutic tool, empirical controlled research on breathwork and ASCs remains limited. Methods We examined the effects of a single session of high ventilation breathwork,...
Research efforts spanning more than seven decades have used functional neuroimaging to investigate whether putative extra‑sensory perception (ESP/receptive psi) has identifiable neural correlates. However, the field lacks a coherent and critical synthesis of its methodological approaches and reported effects. We conducted a systematic review consolidating 143 reports and qualitatively evaluated...
Recent clinical trials have suggested the safety and efficacy of psychedelic therapy for treatment-resistant depression, posttraumatic stress disorder, addiction, and end-of-life distress. While neurobiological mechanisms such as 5-HT2A receptor activation, increased neural entropy, and default mode network modulation have been well-characterized, significantly less attention has been given to...
This study theoretically explores the psychotherapeutic mechanisms of Holotropic Breathwork, an experiential technique developed by Stanislav and Christina Grof, by employing Charles T. Tart's model of altered states of consciousness as a theoretical framework. Through literature review and conceptual analysis, Tart's three conditions of state transition (set, setting, and trigger) and his...
Brain Research BulletinMay 1, 2026Ladina Philomena Gubser, Anna Stefania Trippel, Niklaus Zoelch et al.
Ketamine has been shown to modulate glutamate signaling in animals and may therefore have the potential to restore glutamate imbalances in the brain. Impaired glutamate homeostasis has been implicated in mental health disorders such as substance use disorders (SUDs). Thus, we investigated ketamine's potential to increase glutamate levels in the nucleus accumbens (NAc), a key region for the...
Converging operations allow one to home in on a construct, be this an altered state of consciousness (ASC), or trait and/or state impulsivity. Unfortunately (or, perhaps fortunately), measures that should provide converging operations for such a construct sometimes present with diverging results. Three cases are considered here: trait impulsivity, which should be positively correlated with...
PsyArXivApril 10, 2026George Fejer, Till Holzapfel, Anestis Lalidis Mateo et al.
preprint
Breath-based interactions in virtual reality typically map breathing onto discrete visual objects or downstream physiological proxies. Viscereality takes a different approach, mapping lung volume onto a surrounding space composed of particles arranged in an orb enclosing the participant through interoceptive-exteroceptive sensory substitution, such that inhalation expands the environment...
Altered states of consciousness (ASC) represent a universal human capacity for accessing and transforming the subconscious mind, employed across cultures and millennia through diverse contemplative, somatic, pharmacological, ritual, and technological modalities. This comprehensive review synthesizes evidence from over 25 distinct disciplines spanning five clusters: (A) contemplative and...
ABSTRACT In 1868 eminent Australian author Marcus Clarke wrote a gothic tale for his own Colonial Monthly Magazine titled “Cannabis Indica”, purportedly under the influence of hashish. Contemporaneous reviewers discussed this little-known short story as merely a curio, and modern scholars have followed suit. However, the experimental short story is distinguished as one of the first fictional...
Scientific ReportsMarch 26, 2026Y. J. Gordon, Golan Karvat, Noa Dagan et al.
Altered states of consciousness (ASC) involve shifts in perception, cognition, and awareness, offering a unique lens on the nature of consciousness. Across cultures, rhythmic drumming in the theta range (4-7 Hz) is often used to induce such states, but it remains unclear whether actively enhancing brain rhythms in this range can cause ASC. We tested whether theta-frequency drumming (4 beats per...
Non-ordinary states of consciousness (NOSCs), whether entered via psychedelics, breathwork, hypnosis or other means, show striking therapeutic promise by improving well-being and reducing psychopathology across diverse conditions. While the neuronal dynamics underpinning such therapeutic shifts in consciousness have to some extent been mapped, research has mainly focused on the central nervous...
This theoretical paper proposes a Jamesian framework for clinically informed work with non-ordinary states of consciousness (NOSC) and develops three practical contributions. (1) It reinterprets William James’s “religious experiences” through radical empiricism as a disciplined method of describing lived meaning, value, affect, and relations as data, while bracketing metaphysical claims; on...
Pharos Journal of TheologyFebruary 14, 2026Manat Kanagatov, Tatyana Seryozhkina, Zukhra Ismagambetova et al.
The purpose of this study was to identify the ontological and cultural foundations of the shamanic tradition in the Turkic culture of Kazakhstan through the concept of altered states of consciousness (ASC). The research focused on how ASC structured the shamanic worldview, shaped ritual practices, and transformed under post-traditional social conditions. The methodological framework combined...
Recent research shows that young children frequently report non-ordinary experiences, including extra sensory perceptions, out-of-body experiences, and states of self-transcendence, reflecting relational, pre-linguistic, and weakly individualised forms of consciousness. This paper integrates qualitative studies of children’s experiences with contemporary altered states of consciousness (ASC)...
Immersive virtual environments are increasingly investigated as tools capable of modulating conscious experience, yet the specific contribution of graded immersion to altered states of consciousness (ASC), time perception, and cognition remains unclear. The present study examined how different levels of immersion during videogame play influence subjective experience and post-experience...