Journal of Substance Abuse Treatment
1991
John D. Mcpeake, Bruce P. Kennedy, Sharon M. Gordon
32 citations
Attaining altered states of consciousness is described as a basic human motive. The substance dependent population is distinguished from other populations because they pursue these states destructively by inappropriate use of alcohol and drugs. Despite a body of literature supporting the benefits of altered states of consciousness, alcohol and drug rehabilitation treatment programs fail to...
Pharmacology, Biochemistry, and Behavior
1991
S Ahlenius, K Larsson
31 citations
The administration of 5-methoxy-N,N-di-methyl-tryptamine (5-MeODMT), O-2.0 mg.kg-1 SC -15 min, produced a dose-dependent facilitation of the male rat sexual behavior, as evidenced by a decrease in the number of intromissions to ejaculation and in the ejaculation latency. The effects produced by 5-MeODMT (1 mg.kg-1) were antagonized by pindolol (4 mg.kg-1 SC -30 min), but not pirenperone (0.25...
International Journal of Behavioral Development
December 1, 1990
David Foulkes, Michael Hollifield, Brenda Sullivan et al.
105 citations
Eighty children, 10 boys and 10 girls at each of four ages (5, 6, 7, and 8), were awakened from REM sleep on 10 occasions over the course of three nights in a sleep laboratory to report dreams. They also completed a variety of cognitive skill tests. In confirmation of an earlier, longitudinal study (Foulkes, 1982): Dreams were reported relatively seldom (median report rate of 20%); until age 7,...
Journal of Conflict Resolution
December 1, 1990
David W. Orme-Johnson, Charles N. Alexander, John L. Davies
24 citations
This article replies to a methodological criticism of Orme-Johnson et al., (1988). The original study reported that participants in the Transcendental Meditation (TM) and TM-Sidhi program located in Jerusalem significantly reduced tension in “collective consciousness” and behavior as measured by decreased conflict in Lebanon and improvement on several social indicators in Israel. Specification...
Perceptual and Motor Skills
October 1, 1990
This preliminary research is the first to compare lucid, nightmare, and archetypal-mythological dreams on dimensions important in previous research on each. A first study of 100 subjects showed all three forms significantly correlated with each other and with estimates of dream recall. In a second study, 41 subjects were selected from the above on the basis of relative specialization in each...
Canadian journal of physiology and pharmacology
September 1, 1990
H Mount, P Boksa, I Chaudieu et al.
At concentrations greater than or equal to 100 microM, phencyclidine (PCP), N-(1-(2-thienyl)-cyclohexyl)piperidine (TCP), and MK-801 induced [3H]dopamine release from dissociated cell cultures of rat mesencephalon. This release was Ca2+ independent and tetrodotoxin insensitive. Tetrodotoxin (2 microM) itself had no effect on spontaneous release of [3H]dopamine. [3H]Dopamine release was induced...
Neuroreport
September 1, 1990
L G Sharpe, J H Jaffe
79 citations
Because of anecdotal reports in which ibogaine eliminates opioid withdrawal symptoms in humans, we studied this phenomenon in the rat model. Ibogaine (5, 10, 20 and 40 mg kg-1, s.c.) was administered 15 min before naloxone (0.5 mg kg-1, s.c.) in morphine dependent rats (3 days after the s.c. implantation of a 75 mg morphine pellet). Of the 12 withdrawal signs scored, the only significant...
Journal of Pharmacology and Experimental Therapeutics
August 1, 1990
M. Hiramatsu, Y. Kumagai, S. Unger et al.
The in vitro conversion of (+)-3,4-methylenedioxymethamphetamine and (-)-3,4-methylenedioxymethamphetamine to the corresponding catecholamine, 3,4-dihydroxymethamphetamine (N-methyl-alpha-methyldopamine), by rat liver microsomes was examined. Metabolite formation was monitored after short-term incubations using high-performance liquid chromatography-electrochemical detection to determine...
Journal of Pharmacology and Experimental Therapeutics
August 1, 1990
C. Callaway, Lauren L. Wing, Mark A. Geyer et al.
Methylenedioxymethamphetamine (MDMA) is a phenylethylamine with novel mood-altering properties in humans. MDMA shares the dopamine-releasing properties of amphetamine but has been found to be a more potent releaser of serotonin (5-HT). The present study undertook to determine the relative roles of dopamine and 5-HT release in MDMA-induced locomotor hyperactivity. S-(+)MDMA produced...
Pharmacology, Biochemistry, and Behavior
August 1, 1990
N A Darmani, B R Martin, U Pandey et al.
245 citations
To investigate the possible functional relationship between 5-HT1 and 5-HT2 receptors, we studied the effects of a nonselective 5-HT agonist (5-MeO DMT), a 5-HT1A-selective (8-OH-DPAT) and a 5-HT1B/5-HT1C-selective (TFMPP) agonist on the head-twitch behavior induced by the putative 5-HT2-selective receptor agonist (+/-)-DOI. In the mouse (+/-)-DOI produced the head-twitch response in a...