Life Sciences
December 6, 1982
J A Clemens, M E Roush
8 citations
The effects of 5-methoxy-N,N-dimethyltryptamine (5-MeODMT), a serotonin agonist with a preferential action on presynaptic autoreceptors, on prolactin release in male rats was determined. Basal serum prolactin levels were not altered after administration of 1.0, 2.0, 5.0, 10.0 or 20.0 mg/kg of 5-MeODMT. Pretreatment with 5-MeODMT reduced prolactin release by agents that depend on serotonergic...
British Journal of Medical Psychology
December 1, 1982
F. Kräupl Taylor
The symptoms of depersonalization are examined in the light of the phenomenological views evolved by Franz Brentano. He had come to the conclusion that our conscious experiences are primarily directed towards objects (contents) that are ‘phenomenal’ or ‘intentional’ in the sense that they do not necessarily have counterparts in the external world. In experiencing such an object, a person...
European Journal of Pharmacology
July 30, 1982
J Heym, G F Steinfels, Barry L. Jacobs
21 citations
A comparison was made of the effects of 5-MeoDMT or LSD on serotonergic unit activity in the dorsal raphe nucleus (DRN) and nucleus raphe pallidus (NRP) of freely moving cats. NRP neurons were substantially less responsive than DRN neurons to both drugs. NRP neurons were unresponsive to behaviorally effective low doses of these drugs whereas the activity of DRN neurons was strongly depressed....
Religion
July 1, 1982
Richard A. Hutch
9 citations
Researchers in psychology of religion in America and Britain have inherited the theoretical and research traditions established by W. James, S. Freud and J. Dittes. New nomothetic or theoretical frameworks have been called for in order to organize a plethora of idiographic data. A response to the call has been slow, but Paul Pruyser designated at least six areas in which the development of...
Journal of Pharmacology and Experimental Therapeutics
July 1, 1982
Salomón Z. Langer, Chantal Moret
100 citations
Slices of rat hypothalamus prelabeled with [3H]-5-hydroxytryptamine ([3H]-5-HT) were superfused and the release of the labeled transmitter was elicited either by electrical stimulation or by fenfluramine. Whereas the electrically stimulated release of [3H]-5-HT was completely abolished by removing calcium from the superfusion medium, the fenfluramine-induced release of [3H]-5-HT was...
The Journal of Nervous and Mental Disease
May 1, 1982
Nancy H. Kerr, David Foulkes, Marcella Schmidt
82 citations
Ten college-educated young adults (four sighted, four congenitally blind, and two adventitiously blind) were studied in a sleep laboratory one night a week for 8 weeks. Dream reports were collected from electroencephalogram-defined sleep onset, rapid eye movement sleep, and non-rapid eye movement sleep, following a standard awakening schedule and interview format. Dream reports were analyzed in...
Psychopharmacology
March 1, 1982
Randall L. Commissaris, Richard H. Rech
The effects of diazepam quipazine, lysergic acid diethylamide (LSD), and 2,5-dimethoxy-4-methylamphetamine (DOM) were examined on a conditioned suppression paradigm. Food-deprived rats were trained to drink a liquid diet from a tube. Subsequently, intermittent 7-s tones were presented during the daily 10-min sessions, the tube being electrified during the last 5 s of each tone. The subject...
Neuroscience & Biobehavioral Reviews
1982
Randall L. Commissaris, M Davis
25 citations
The present studies examined the role of the spinal cord and the brain in mediating the effects of the hallucinogens N,N-dimethyltryptamine (DMT) and 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) on the acoustic startle response in the rat. Systemic administration of these agents, which distributes to both the brain and spinal cord, produced opposite effects, as DMT depressed and 5-MeODMT...
Cortex
December 1, 1981
Nancy H. Kerr, David Foulkes
Our paper addresses, as did a recent study by Greenwood et al. (1977), the question of differential right vs. left hemispheric involvement in REM-sleep dreaming. A male subject with extensive lesioning of the right hemisphere and consequent contralateral homonymous hemianopia was studied for 2 nights in a sleep laboratory where a dream report was collected following each of 6 awakenings from...
Pharmacology, Biochemistry, and Behavior
October 1981
Randall L. Commissaris, Richard H. Rech
The present study examined the disruptive effects of the phenethylamine hallucinogen 2,5-dimethoxy-4-methylamphetamine (DOM) and the putative 5-hydroxytryptamine (5-HT) agonist quipazine on fixed ratio-40 (FR-40) operant responding alone or after pretreatment with putative 5-HT antagonist metergoline. Food-deprived male rats were trained to bar press on a FR-40 schedule for food reinforcements;...