Do functional relationships exist between 5-HT1A and 5-HT2 receptors?
Pharmacology, biochemistry, and behavior August 1, 1990 N A Darmani, B R Martin, U Pandey et al. 245 citations
To investigate the possible functional relationship between 5-HT1 and 5-HT2 receptors, we studied the effects of a nonselective 5-HT agonist (5-MeO DMT), a 5-HT1A-selective (8-OH-DPAT) and a 5-HT1B/5-HT1C-selective (TFMPP) agonist on the head-twitch behavior induced by the putative 5-HT2-selective receptor agonist (+/-)-DOI. In the mouse (+/-)-DOI produced the head-twitch response in a...