Journal of Sleep Research
August 9, 2020
P. Bugalho, F. Ladeira, Raquel Barbosa et al.
Cross‐sectional studies suggest a correlation between alterations in dream content reports and executive dysfunction tests in Parkinson’s disease (PD), but this has not been assessed in longitudinal studies. Our objective was to assess the predictive value of dream content for progression of cognitive dysfunction in PD. We prospectively addressed all consecutive, non‐demented patients with PD...
August 7, 2020
Olga V. Mitina, М.а. Винникова, А. Н. Решетилов et al.
preprint
## AimInvestigate accounts from breath-holding freedivers about high efficiency in coping with adversity and pain, immediately quitting addictions, attaining harmonious meaningful life, becoming perspicacious and compassionate, getting spontaneous religious experience. ## Findings Full Mystical Experience is confirmed to happen in freediving, i.e. it is the same Mystical experience found in...
Molecular Neurobiology
August 2020
Sinead E Shortall, Angus M Brown, Eliot Newton-Mann et al.
Despite several compounds entering clinical trials for the negative and cognitive symptoms of schizophrenia, few have progressed beyond phase III. This is partly attributed to a need for improved preclinical models, to understand disease and enable predictive evaluation of novel therapeutics. To this end, one recent approach incorporates "dual-hit" neurodevelopmental insults like neonatal...
International Journal of Information Technology and Management
August 1, 2020
Archana Tangri Archana Tangri, Dr. Priti Dubey Dr. Priti Dubey
Meditation is a type of mental exercise that aims to increase a person's capacity for selfawareness.A new state of awareness is induced, resulting in positive outcomes for all of humanity.Focusing on a single point, such as the breath, body, or mantra, is possible. People use it for everythingfrom pain relief to stress relief to enhanced mental clarity. Having an optimistic outlook on life is a...
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
August 2020
Małgorzata Frankowska, Joanna Miszkiel, Lucyna Pomierny-Chamioło et al.
The abundance of research indicates that enriched environment acts as a beneficial factor reducing the risks of relapse in substance use disorder. There is also strong evidence showing the engagement of brain dopaminergic and glutamatergic signaling through the dopamine D2-like and metabotropic glutamate type 5 (mGlu5) receptors, respectively, that has a direct impact on drug reward and drug...
Frontiers in Psychology
July 29, 2020
Jared R. Lindahl, D. James Cooper, Nathan E. Fisher et al.
2 citations
Studies in the psychology and phenomenology of religious experience have long acknowledged similarities with various forms of psychopathology. Consequently, it has been important for religious practitioners and mental health professionals to establish criteria by which religious, spiritual, or mystical experiences can be differentiated from psychopathological experiences. Many previous attempts...
July 28, 2020
Niklas Serning, Nina Lyon
1 citation
Psychedelics are newly respectable. Evidence suggests that a variety of ills, from anxiety and depression to addictions and post-traumatic stress disorder, respond to them in a way hitherto unseen within psychiatry. The researchers involved have been careful to clean up the reputation of a class of drugs that, despite a wealth of promising evidence for their therapeutic effects in the 1960s and...
Preprints.org
July 22, 2020
Alessandro Frolli, Maria Carla Ricci, Antonella Cavallaro et al.
3 citations
preprint
The developmental phase of adolescence is characterized by a multitude of neurocognitive and psychosocial changes and is therefore considered one of the most critical developmental periods of life. Experimentation on the use of substances often begins in adolescence and so does the addiction process. Most research in human subjects shows that chronic cannabis abuse is the cause of the...
Cureus
July 21, 2020
Shweta Patel, Sahar Khan, M Saipavankumar et al.
69 citations
Marijuana is one of the most abused substances in the world. Marijuana is getting legalized around the world. So, it is crucial to understand its effect on our mental health. Its impact on the schizophrenia spectrum needs our special attention. Even though marijuana has been around for a long time, its exact effects are still unknown. Schizophrenia is a chronic illness affecting approximately...
Frontiers in Neuroscience
July 21, 2020
Kelly F Paton, Andrew Biggerstaff, Sophia Kaska et al.
In the search for safer, non-addictive analgesics, kappa opioid receptor (KOPr) agonists are a potential target, as unlike mu-opioid analgesics, they do not have abuse potential. Salvinorin A (SalA) is a potent and selective KOPr agonist, however, clinical utility is limited by the short duration of action and aversive side effects. Biasing KOPr signaling toward G-protein activation has been...