Schizophrenia Research
January 9, 2021
Leah G. Pope, M. Manseau, M. Kelley et al.
OBJECTIVE The nature of associations between recent cannabis use and negative symptoms, positive symptoms, and neurocognitive deficits remains unclear. In a relatively large sample of well-characterized patients with first-episode psychosis, we hypothesized that, compared to first-episode patients without cannabis use in the three months prior to first hospitalization, those having used...
Psychopharmacology
January 9, 2021
C. J. Healy
95 citations
RationaleMemory plays a central role in the psychedelic experience. The spontaneous recall and immersive reliving of autobiographical memories has frequently been noted by researchers and clinicians as a salient phenomenon in the profile of subjective effects of classic psychedelic drugs such as psilocybin, LSD, and ayahuasca. The ability for psychedelics to provoke vivid memories has been...
Biological Psychiatry
January 8, 2021
Mingzheng Wu, Samuel Minkowicz, V. Dumrongprechachan et al.
96 citations
BACKGROUND Ketamine elicits rapid onset antidepressant effects in patients with clinical depression through mechanisms hypothesized to involve the genesis of neocortical dendritic spines and synapses. Yet, the observed changes in dendritic spine morphology usually emerge well after ketamine clearance, raising questions about the link between rapid behavioral effects of ketamine and plasticity....
PsyArXiv
January 5, 2021
Anna Ciaunica, Bruna Petreca, Aikaterini Fotopoulou et al.
preprint
In his seminal paper ‘Whatever next? Predictive brains, situated agents, and the future of cognitive science’ Andy Clark (2013) argued that the brain’s job is to predict whatever information is coming ‘next’ on the basis of prior inputs. This is because the organism’s survival is key to biological agents such as humans. Survival however crucially depends on rapid and accurate information...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
January 2, 2021
Agnieszka Pałucha-Poniewiera, K. Podkowa, Anna Rafało-Ulińska
Ketamine produces a rapid antidepressant effect, but its use can be associated with serious side effects. Hence, other therapeutic options that will allow us to obtain a quick and safe antidepressant effect by modulating glutamatergic transmission are needed. Antagonists of mGlu2/3 receptors, which share some mechanisms of action with ketamine, may be good candidates to obtain this effect....
Chiasmi International
2021
Giulia Andreini, Chiasmi International
1 citation
Always rich in heterogeneous suggestions, Merleau-Pontian reflection does not fail to address the status of oneiric experience, which is as complex as it is neglected or even trivialized in phenomenological studies. Although it is sometimes taken into consideration, notably in Sartrean analyses, this is only to reconduct it to the activity of the imagining consciousness. This contribution thus...
Libro Comunicaciones
2021
Maitane Oscoz-Irurozqui, Maria Guardiola-Ripoll, Carmen Almodóvar-Payá et al.
1. Objectives: While endocannabinoid system seems to be involved in processes underlying psychosis, research about Cannabinoid Receptor 2 gene (CNR2) is scarce and inconclusive. Some few reports indicate that CNR2 plays a role in psychiatric conditions, including depression or drug addiction (Onaivi et al., 2009). We aimed to evaluate the role of CNR2 and its interplay with cannabis on...
New York History
2021
Devin R. Lander
Reviewed by: American Trip: Set, Setting, and the Psychedelic Experience in the Twentieth Century by Ido Hartogsohn Devin Lander (bio) American Trip: Set, Setting, and the Psychedelic Experience in the Twentieth Century By Ido Hartogsohn. Cambridge, MA: MIT Press, 2020. 432 pages, 6" x 9". $35.00 paper, $35.00 ebook. Ido Hartogsohn, assistant professor in the program for science, technology,...
Proceedings for Annual Meeting of The Japanese Pharmacological Society
2021
Satoshi Deyama, Katsuyuki Kaneda
The antidepressant actions of the NMDA receptor antagonist ketamine require activity-dependent release of brain-derived neurotrophic factor (BDNF) in the medial prefrontal cortex (mPFC). Our recent study shows a similar requirement for vascular endothelial growth factor (VEGF). Previous studies have reported that both BDNF and VEGF activate TRPC3 and TRPC6 via diacylglycerol production, and...
National Psychological Journal
2021
O. V. Gordeeva
Relevance of the article. Without the use of the self-report method, it is impossible to study a number of psychological phenomena (for example, hallucinosis, the study of which allows us to understand the mechanisms of formation of perceptual, dream, mnestic, imaginative images). At the same time, the possibilities and limitations of two variants of the self-report method — an interview about...