Neuroscience and Biobehavioral Reviews - The Consciousness Library

Dreaming for two: A systematic review of mental sleep activity during pregnancy.

Neuroscience and Biobehavioral Reviews August 1, 2024 Serena Scarpelli, Valentina Alfonsi, Luigi De Gennaro et al.

Changes in sleep and dreams are often observed during pregnancy. Dreaming may represent privileged access to the inner world of individuals, providing relevant information about their well-being. For this reason, a growing but heterogeneous literature has investigated dream experiences of pregnant women. The present paper aimed to systematically review the available evidence on the relationship...

DOI: 10.1016/j.neubiorev.2024.105763 Full text Dreaming Continuity hypothesis Emotional regulation Mental sleep activity +3

Exploring the impact of music on response to ketamine/esketamine: A scoping review.

Neuroscience and Biobehavioral Reviews July 1, 2024 Mina Kheirkhah, Allison C. Nugent, Alicia A Livinski et al. 13 citations

Music and ketamine are both known to affect therapeutic outcomes, but few studies have investigated their co-administration. This scoping review describes the existing literature on the joint use of music and ketamine-or esketamine (the S(+) enantiomer of ketamine)-in humans. The review considers that extant studies have explored the intersection of ketamine/esketamine and music in healthy...

DOI: 10.1016/j.neubiorev.2024.105693 Full text Esketamine Anesthesia Ketamine-assisted therapy Music intervention +2

Effects of meditation on neural responses to pain: A systematic review and meta-analysis of fMRI studies.

Neuroscience and Biobehavioral Reviews July 1, 2024 Cheng Fan, Mengjiao Wu, Hong Liu et al.

This systematic review investigates the impact of meditation on neural responses to pain, as measured by functional magnetic resonance imaging (fMRI). Up to March 2024, we conducted searches across four databases for human studies implementing fMRI to assess the efficacy of meditation for pain relief. Eighteen studies met the inclusion criteria. Our systematic review indicates that activation...

DOI: 10.1016/j.neubiorev.2024.105735 Full text Meditation Emotional pain FMRI Meta-analysis +2

A measure centrality index for systematic empirical comparison of consciousness theories.

Neuroscience and Biobehavioral Reviews June 1, 2024 Robert Chis-Ciure, Lucia Melloni, Georg Northoff

Consciousness science is marred by disparate constructs and methodologies, making it challenging to systematically compare theories. This foundational crisis casts doubts on the scientific character of the field itself. Addressing it, we propose a framework for systematically comparing consciousness theories by introducing a novel inter-theory classification interface, the Measure Centrality...

DOI: 10.1016/j.neubiorev.2024.105670 Full text Consciousness science Global neuronal workspace Integrated information theory Inter-theoretic empirical translation +2

Using caffeine as a chemical means to induce flow states.

Neuroscience and Biobehavioral Reviews April 1, 2024 Niklas Reich, Michael Mannino, Steven Kotler

Flow is an intrinsically rewarding state characterised by positive affect and total task absorption. Because cognitive and physical performance are optimal in flow, chemical means to facilitate this state are appealing. Caffeine, a non-selective adenosine receptor antagonist, has been emphasized as a potential flow-inducer. Thus, we review the psychological and biological effects of caffeine...

DOI: 10.1016/j.neubiorev.2024.105577 Full text Altered consciousness ADHD Adenosine receptor antagonist Caffeine +6

What is sleep exactly? Global and local modulations of sleep oscillations all around the clock.

Neuroscience and Biobehavioral Reviews December 1, 2023 Thomas Andrillon, Delphine Oudiette 44 citations

Wakefulness, non-rapid eye-movement (NREM) and rapid eye-movement (REM) sleep differ from each other along three dimensions: behavioral, phenomenological, physiological. Although these dimensions often fluctuate in step, they can also dissociate. The current paradigm that views sleep as made of global NREM and REM states fail to account for these dissociations. This conundrum can be dissolved...

DOI: 10.1016/j.neubiorev.2023.105465 Full text Dreaming Attention Behaviour Cognition +7

High ventilation breathwork practices: An overview of their effects, mechanisms, and considerations for clinical applications.

Neuroscience and Biobehavioral Reviews December 1, 2023 Guy W. Fincham, Amy Kartar, Malin V. Uthaug et al. 41 citations

High Ventilation Breathwork (HVB) refers to practices employing specific volitional manipulation of breathing, with a long history of use to relieve various forms of psychological distress. This paper seeks to offer a consolidative insight into potential clinical application of HVB as a treatment of psychiatric disorders. We thus review the characteristic phenomenological and neurophysiological...

DOI: 10.1016/j.neubiorev.2023.105453 Full text Breathwork PTSD Pranayama Alkalosis +11

Libet's Legacy: A Primer to the Neuroscience of Volition.

Neuroscience and Biobehavioral Reviews December 1, 2023 T. Dominik, Alfred Mele, Aaron Schurger et al.

The neuroscience of volition is an emerging subfield of the brain sciences, with hundreds of papers on the role of consciousness in action formation published each year. This makes the state-of-the-art in the discipline poorly accessible to newcomers and difficult to follow even for experts in the field. Here we provide a comprehensive summary of research in this field since its inception that...

DOI: 10.1016/j.neubiorev.2023.105503 Full text

Functional imaging studies of acute administration of classic psychedelics, ketamine, and MDMA: Methodological limitations and convergent results.

Neuroscience and Biobehavioral Reviews November 1, 2023 Sophia Linguiti, Jacob W Vogel, Valerie J Sydnor et al. 15 citations

Functional magnetic resonance imaging (fMRI) is increasingly used to non-invasively study the acute impact of psychedelics on the human brain. While fMRI is a promising tool for measuring brain function in response to psychedelics, it also has known methodological challenges. We conducted a systematic review of fMRI studies examining acute responses to experimentally administered psychedelics...

DOI: 10.1016/j.neubiorev.2023.105421 Full text Ketamine LSD MDMA Psilocybin +8

A construct-first approach to consciousness science.

Neuroscience and Biobehavioral Reviews November 1, 2023 Peter Fazekas, A. Cleeremans, Morten Overgaard

We propose a new approach to consciousness science that instead of comparing complex theoretical positions deconstructs existing theories, takes their central assumptions while disregarding their auxiliary hypotheses, and focuses its investigations on the main constructs that these central assumptions rely on (like global workspace, recurrent processing, metarepresentation). Studying how these...

DOI: 10.1016/j.neubiorev.2023.105480 Full text

The zebrafish for preclinical psilocybin research.

Neuroscience and Biobehavioral Reviews October 1, 2023 Omer A. Syed, Benjamin Tsang, Robert Gerlai 7 citations

In this review, we discuss the possible utility of zebrafish in research on psilocybin, a psychedelic drug whose recreational use as well as possible clinical application are gaining increasing interest. First, we review behavioral tests with zebrafish, focussing on anxiety and social behavior, which have particular relevance in the context of psilocybin research. Next, we briefly consider...

DOI: 10.1016/j.neubiorev.2023.105381 Full text Anxiety Psilocybin Affective disorders Social behavior +9

Insight and the selection of ideas.

Neuroscience and Biobehavioral Reviews October 1, 2023 Ruben Laukkonen, Margaret Webb, Carola Salvi et al.

Perhaps it is no accident that insight moments accompany some of humanity's most important discoveries in science, medicine, and art. Here we propose that feelings of insight play a central role in (heuristically) selecting an idea from the stream of consciousness by capturing attention and eliciting a sense of intuitive confidence permitting fast action under uncertainty. The mechanisms...

DOI: 10.1016/j.neubiorev.2023.105363 Full text

The relationship between the default mode network and the theory of mind network as revealed by psychedelics - A meta-analysis.

Neuroscience and Biobehavioral Reviews September 1, 2023 Carla Soares, Gerardo Gonzalo, João Castelhano et al.

The Default Mode Network (DMN) and the Theory of Mind (ToM) networks play a crucial role in our understanding of the neurocognition of the self. The DMN is commonly associated with introspection, while the ToM is involved in perspective-taking. There is no research investigating the overlap between the DMN and ToM in relation to causal effects such as induced by psychedelics, and their precise...

DOI: 10.1016/j.neubiorev.2023.105325 Full text Default mode network Meta-analysis Psychedelics Theory of mind

Understanding visual hallucinations: A new synthesis.

Neuroscience and Biobehavioral Reviews July 1, 2023 Daniel Collerton, James Barnes, Nico J Diederich et al. 80 citations

Despite decades of research, we do not definitively know how people sometimes see things that are not there. Eight models of complex visual hallucinations have been published since 2000, including Deafferentation, Reality Monitoring, Perception and Attention Deficit, Activation, Input, and Modulation, Hodological, Attentional Networks, Active Inference, and Thalamocortical Dysrhythmia Default...

DOI: 10.1016/j.neubiorev.2023.105208 Full text Anomalous experiences Charles bonnet syndrome Eye disease Lewy body +5

The acute effects of psychoactive drugs on emotional episodic memory encoding, consolidation, and retrieval: A comprehensive review.

Neuroscience and Biobehavioral Reviews July 1, 2023 Manoj K. Doss, Harriet de Wit, David A Gallo 30 citations

Psychoactive drugs modulate learning and emotional processes in ways that could impact their recreational and medical use. Recent work has revealed how drugs impact different stages of processing emotional episodic memories, specifically encoding (forming memories), consolidation (stabilizing memories), and retrieval (accessing memories). Drugs administered before encoding may preferentially...

DOI: 10.1016/j.neubiorev.2023.105188 Full text Ketamine MDMA THC Alcohol +13

Relating different dimensions of bodily experiences: Review and proposition of an integrative model relying on phenomenology, predictive brain and neuroscience of the self.

Neuroscience and Biobehavioral Reviews May 1, 2023 Lisa Raoul, Marie-Hélène Grosbras 15 citations

How we mentally experience our body has been studied in a variety research domains. Each of these domains focuses in its own ways on different aspects of the body, namely the neurophysiological, perceptual, affective or social components, and proposes different conceptual taxonomies. It is therefore difficult to find one's way through this vast literature and to grasp the relationships between...

DOI: 10.1016/j.neubiorev.2023.105141 Full text Bodily self-consciousness Body Phenomenal consciousness

Topographic-dynamic reorganisation model of dreams (TRoD) - A spatiotemporal approach.

Neuroscience and Biobehavioral Reviews May 1, 2023 Georg Northoff, Andrea Scalabrini, Stuart Fogel 13 citations

Dreams are one of the most bizarre and least understood states of consciousness. Bridging the gap between brain and phenomenology of (un)conscious experience, we propose the Topographic-dynamic Re-organization model of Dreams (TRoD). Topographically, dreams are characterized by a shift towards increased activity and connectivity in the default-mode network (DMN) while they are reduced in the...

DOI: 10.1016/j.neubiorev.2023.105117 Full text Dream Dynamic Re-organization Self +2

Sleep and dreaming in the light of reactive and predictive homeostasis.

Neuroscience and Biobehavioral Reviews April 1, 2023 Péter Simor, Philippe Peigneux, Róbert Bódizs

Dreams are often viewed as fascinating but irrelevant mental epihenomena of the sleeping mind with questionable functional relevance. Despite long hours of oneiric activity, and high individual differences in dream recall, dreams are lost into oblivion. Here, we conceptualize dreaming and dream amnesia as inherent aspects of the reactive and predictive homeostatic functions of sleep. Mental...

DOI: 10.1016/j.neubiorev.2023.105104 Full text Dreaming Homeostasis Memory Mind-wandering +2

First few seconds for flow: A comprehensive proposal of the neurobiology and neurodynamics of state onset.

Neuroscience and Biobehavioral Reviews December 1, 2022 Steven Kotler, Michael Mannino, Scott Kelso et al. 44 citations

Flow is a cognitive state that manifests when there is complete attentional absorption while performing a task. Flow occurs when certain internal as well as external conditions are present, including intense concentration, a sense of control, feedback, and a balance between the challenge of the task and the relevant skillset. Phenomenologically, flow is accompanied by a loss of...

DOI: 10.1016/j.neubiorev.2022.104956 Full text Altered consciousness Flow Network neuroscience Systems neuroscience

Towards characterizing the canonical computations generating phenomenal experience.

Neuroscience and Biobehavioral Reviews November 1, 2022 Megan A. K. Peters

Science and philosophy have long struggled with how to even begin studying the neural or computational basis of qualitative experience. Here I review psychological, neuroscience, and philosophical literature to reveal how perceptual metacognition possesses five unique properties that provide a powerful opportunity for studying the neural and computational correlates of subjective experience:...

DOI: 10.1016/j.neubiorev.2022.104903 Full text Phenomenology Computational modeling Consciousness Metacognition +1

Focused attention meditation in healthy adults: A systematic review and meta-analysis of cross-sectional functional MRI studies.

Neuroscience and Biobehavioral Reviews October 1, 2022 Saampras Ganesan, Emillie Beyer, Bradford A. Moffat et al.

Meditation trains the mind to focus attention towards an object or experience. Among different meditation techniques, focused attention meditation is considered foundational for more advanced practices. Despite renewed interest in its functional neural correlates, there is no unified neurocognitive model of focused attention meditation developed via quantitative synthesis of contemporary...

DOI: 10.1016/j.neubiorev.2022.104846 Full text Meditation Activation likelihood estimation Focused attention Functional MRI +4

A voice without a mouth no more: The neurobiology of language and consciousness.

Neuroscience and Biobehavioral Reviews September 1, 2022 Jeremy I Skipper

Most research on the neurobiology of language ignores consciousness and vice versa. Here, language, with an emphasis on inner speech, is hypothesised to generate and sustain self-awareness, i.e., higher-order consciousness. Converging evidence supporting this hypothesis is reviewed. To account for these findings, a 'HOLISTIC' model of neurobiology of language, inner speech, and consciousness is...

DOI: 10.1016/j.neubiorev.2022.104772 Full text Default mode network Consciousness Core-periphery Efference copy +7

Psychedelic resting-state neuroimaging: A review and perspective on balancing replication and novel analyses.

Neuroscience and Biobehavioral Reviews July 1, 2022 Drummond E-Wen Mcculloch, Gitte Moos Knudsen, Frederick Streeter Barrett et al. 14 citations

Clinical research into serotonergic psychedelics is expanding rapidly, showing promising efficacy across myriad disorders. Resting-state functional magnetic resonance imaging (rs-fMRI) is a commonly used strategy to identify psychedelic-induced changes in neural pathways in clinical and healthy populations. Here we, a large group of psychedelic imaging researchers, review the 42 research...

DOI: 10.1016/j.neubiorev.2022.104689 Full text DMT LSD Psilocin Psilocybin +10

(R)-ketamine as prophylactic and therapeutic drug for neurological disorders: beyond depression.

Neuroscience and Biobehavioral Reviews June 1, 2022 Xingming Wang, Jianjun Yang, Kenji Hashimoto

Neurological disorders are the leading cause of disability and the second leading cause of death worldwide. The increasing social and economic burdens of neurological disorders are driven by global population growth and aging. Depression is a common psychiatric symptom in numerous neurological disorders. It is also a risk factor for Alzheimer's disease (AD) and other dementias, Parkinson's...

DOI: 10.1016/j.neubiorev.2022.104762 Full text

Evolutionary Origin and the Development of Consciousness.

Neuroscience and Biobehavioral Reviews December 1, 2021 Ilya Kanaev 16 citations

This review seeks to combine advances in anthropology and neuroscience to investigate the adaptive value of human consciousness. It uses an interdisciplinary perspective on the origin of consciousness to refute the most common fallacies in considering consciousness, particularly, disregarding the evolutionary origin of the subjective reality in looking for the neural correlates of consciousness...

DOI: 10.1016/j.neubiorev.2021.12.034 Full text

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