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João Castelhano

2 papers in the library · 34 citations · publishing 2021-2023

Papers

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The relationship between the default mode network and the theory of mind network as revealed by psychedelics - A meta-analysis.

Neuroscience & Biobehavioral Reviews September 1, 2023 Carla Soares, Gerardo Gonzalo, João Castelhano et al.

The Default Mode Network (DMN) and the Theory of Mind (ToM) networks play a crucial role in our understanding of the neurocognition of the self. The DMN is commonly associated with introspection, while the ToM is involved in perspective-taking. There is no research investigating the overlap between the DMN and ToM in relation to causal effects such as induced by psychedelics, and their precise...

The Effects of Tryptamine Psychedelics in the Brain: A meta-Analysis of Functional and Review of Molecular Imaging Studies

Frontiers in Pharmacology September 29, 2021 João Castelhano, Gisela Lima, Marta Teixeira et al. 34 citations

There is an increasing interest in the neural effects of psychoactive drugs, in particular tryptamine psychedelics, which has been incremented by the proposal that they have potential therapeutic benefits, based on their molecular mimicry of serotonin. It is widely believed that they act mainly through 5HT2A receptors but their effects on neural activation of distinct brain systems are not...