Headache
February 1, 2026
Faraidoon Haghdoost, Dilara Bahceci, Candice Delcourt et al.
This study was undertaken to identify gaps in cluster headache management, highlight patient-prioritized research needs, and assess patient interest in, and preferences for, clinical trial participation. Many people with cluster headache still lack effective treatment options to control or prevent attacks. There is a critical need for more studies, particularly clinical trials, in this field....
Neuroscience & Biobehavioral Reviews
January 24, 2026
Omer A. Syed, Benjamin Tsang, Sean M. Nestor et al.
Psilocybin-assisted therapy (PAT) is an emerging intervention for depression. Though several clinical trials report promising results for PAT in treating depression, there remains a need for consensus on optimal methodologies and standardization of PAT protocols. The objective of this review was to assess the efficacy of PAT in treating depressive symptoms and to systematically examine the...
Neuroscience & Biobehavioral Reviews
May 9, 2025
Rotem Petranker, Benjamin Tsang, Omer A. Syed
3 citations
Microdosing, the repeated use of psychedelic substances at low doses, is growing in popularity among recreational consumers. While this practice is associated with many benefits to mood, well-being and health, research in this area is in its early stages and predominantly centered on human applications. In this narrative review, we synthesize the findings from studies investigating the effects...
npj Mental Health Research
November 8, 2023
Omer A. Syed, Benjamin Tsang
4 citations
The recent years have seen an unprecedented surge of psychedelic research. Studies with psilocybin (colloquially known as magic mushrooms), in particular, have shown promise in ameliorating symptoms of treatment-refractory depression, anxiety, and substance use disorder, among others 1 , 2 . Microdosing, the practice of regularly taking roughly a tenth of full psychedelic doses, is becoming...
Neuroscience and Biobehavioral Reviews
October 1, 2023
Omer A. Syed, Benjamin Tsang, Robert Gerlai
7 citations
In this review, we discuss the possible utility of zebrafish in research on psilocybin, a psychedelic drug whose recreational use as well as possible clinical application are gaining increasing interest. First, we review behavioral tests with zebrafish, focussing on anxiety and social behavior, which have particular relevance in the context of psilocybin research. Next, we briefly consider...