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Saampras Ganesan

8 papers in the library · 49 citations · publishing 2022-2026

Papers

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The Meta-Awareness – Equanimity Framework of Self for Psychiatry: Phenomenological Insights from Psychosis and Mindfulness

October 4, 2026 Saampras Ganesan, Antoine Lutz, Andrew Zalesky et al. preprint

Psychiatric disorders remain a major global health challenge, yet research does not adequately incorporate first-person lived experience. A central component of lived experience is the sense of self, which is often profoundly altered in psychiatric conditions and can serve as a prognostic phenomenological marker, particularly in psychosis. In psychiatry, the most minimal form of self, i.e., the...

Neurofeedback Training Facilitates Awareness and Enhances Emotional Well-being Associated with Real-World Meditation Practice: A 7-T MRI Study.

Mindfulness September 26, 2025 Saampras Ganesan, Nicholas T. van Dam, Sunjeev K. Kamboj et al. 3 citations

Objectives: Novice meditators often struggle to recognise and intentionally disengage from self-referential thought during meditation. We investigated whether personalised high-precision neurofeedback (NF) training improves volitional disengagement from self-referential thought during meditation and enhances meditation's outcomes. Method: In a single-blind, controlled study, novices received 2...

DOI: 10.1007/s12671-025-02671-z (opens in new tab) Full text (opens in new tab) Meditation Neurofeedback Dorsolateral prefrontal cortex Posterior cingulate cortex +3

ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices.

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging April 1, 2025 Saampras Ganesan, Fernando A Barrios, Ishaan Batta et al. 6 citations

Meditation is a family of ancient and contemporary contemplative mind-body practices that can modulate psychological processes, awareness, and mental states. Over the last 40 years, clinical science has manualized meditation practices and designed various meditation interventions that have shown therapeutic efficacy for disorders including depression, pain, addiction, and anxiety. Over the past...

High-precision neurofeedback-guided meditation training optimises real-world self-guided meditation practice for well-being

bioRxiv (Cold Spring Harbor Laboratory) October 26, 2024 Saampras Ganesan, Nicholas T. van Dam, Sunjeev K. Kamboj et al. 3 citations preprint

Meditation can benefit well-being and mental health, but novices often struggle to effectively recognize and disengage from mental processes during meditation due to limited awareness, potentially diminishing meditation's benefits. We investigated whether personalised high-precision neurofeedback (NF) can improve disengagement from mental activity during meditation and enhance meditation's...

DOI: 10.1101/2024.10.25.618656 (opens in new tab) Full text (opens in new tab) Meditation Neurofeedback Disengagement theory Dorsolateral prefrontal cortex +6

Within-subject reliability of brain networks during advanced meditation: An intensively sampled 7 Tesla MRI case study.

Human Brain Mapping May 1, 2024 Saampras Ganesan, Winson F.z. Yang, Avijit Chowdhury et al. 23 citations

Advanced meditation such as jhana meditation can produce various altered states of consciousness (jhanas) and cultivate rewarding psychological qualities including joy, peace, compassion, and attentional stability. Mapping the neurobiological substrates of jhana meditation can inform the development and application of advanced meditation to enhance well-being. Only two prior studies have...

DOI: 10.1002/hbm.26666 (opens in new tab) Full text (opens in new tab) Advanced meditation Consciousness Intraclass correlation icc Jhana +2

Meditation attenuates default-mode activity: A pilot study using ultra-high field 7 Tesla MRI.

Brain Research Bulletin October 15, 2023 Saampras Ganesan, Bradford A. Moffat, Nicholas T. van Dam et al. 13 citations

Mapping the neurobiology of meditation has been bolstered by functional MRI (fMRI) research, with advancements in ultra-high field 7 Tesla fMRI further enhancing signal quality and neuroanatomical resolution. Here, we utilize 7 Tesla fMRI to examine the neural substrates of meditation and replicate existing widespread findings, after accounting for relevant physiological confounds. In this...

Meditation attenuates Default-mode activity: a pilot study using ultra-high strength MRI

bioRxiv (Cold Spring Harbor Laboratory) January 3, 2023 Saampras Ganesan, Bradford A. Moffat, Nicholas T. van Dam et al. 1 citation preprint

Abstract Objectives Mapping the neurobiology of meditation using 3 Tesla functional MRI (fMRI) has burgeoned recently. However, limitations in signal quality and neuroanatomical resolution have impacted reliability and precision of extant findings. Although ultra-high strength 7 Tesla MRI overcomes these limitations, investigation of meditation using 7 Tesla fMRI is still in its infancy....

Focused attention meditation in healthy adults: A systematic review and meta-analysis of cross-sectional functional MRI studies.

Neuroscience & Biobehavioral Reviews October 1, 2022 Saampras Ganesan, Emillie Beyer, Bradford A. Moffat et al.

Meditation trains the mind to focus attention towards an object or experience. Among different meditation techniques, focused attention meditation is considered foundational for more advanced practices. Despite renewed interest in its functional neural correlates, there is no unified neurocognitive model of focused attention meditation developed via quantitative synthesis of contemporary...

DOI: 10.1016/j.neubiorev.2022.104846 (opens in new tab) Full text (opens in new tab) Meditation Activation likelihood estimation Focused attention Functional MRI +4