PLoS One
2023
Marco Schlosser, Harriet Demnitz-King, Thorsten Barnhofer et al.
13 citations
Older adults with subjective cognitive decline (SCD) recruited from memory clinics have an increased risk of developing dementia and regularly experience reduced psychological well-being related to memory concerns and fear of dementia. Research on improving well-being in SCD is limited and lacks non-pharmacological approaches. We investigated whether mindfulness-based and health education...
PLoS One
2023
Marco Schlosser, Olga Klimecki, Fabienne Collette et al.
6 citations
As the world population is ageing, it is vital to understand how older adults can maintain and deepen their psychological well-being as they are confronted with the unique challenges of ageing in a complex world. Theoretical work has highlighted the promising role of intentional mental training such as meditation practice for enhancing human flourishing. However, meditation-based randomised...
Trends in Cognitive Sciences
December 22, 2022
Christopher Timmermann, Prisca R. Bauer, Olivia Gosseries et al.
145 citations
No contemporary unifying framework has been provided for the study of non-ordinary states of consciousness (NSCs) despite increased interest in hypnosis, meditation, and psychedelics. NSCs induce shifts in experiential contents (what appears to the experiencer) and/or structure (how it appears). This can allow the investigation of the plastic and dynamic nature of experience from a multiscale...
October 31, 2022
Marco Schlosser, Olga Klimecki, Fabienne Collette et al.
Objectives: As the world population is ageing, it is vital to understand how older adults can maintain and deepen their psychological well-being as they are confronted with the unique challenges of ageing in a complex and vulnerable world. Theoretical work has highlighted the promising role of intentional mental training such as meditation practice for enhancing human flourishing. However,...
JAMA Neurology
October 10, 2022
Gaël Chételat, Antoine Lutz, Olga Klimecki et al.
45 citations
Importance: No lifestyle-based randomized clinical trial directly targets psychoaffective risk factors of dementia. Meditation practices recently emerged as a promising mental training exercise to foster brain health and reduce dementia risk. Objective: To investigate the effects of meditation training on brain integrity in older adults. Design, Setting, and Participants: Age-Well was a...
August 2, 2022
Arnaud Poublan-Couzardot, Giuseppe Pagnoni, Antoine Lutz
10 citations
preprint
The perception of pain is sensitive to various mental processes such as expectation about the nociceptive stimulus or individual differences in the affective and cognitive evaluations of pain. A promising approach to the investigation of the neurocomputational principles of pain perception is the theory of predictive processing which offers a general framework to understand perception and...
American Journal of Psychiatry
July 28, 2022
Joseph Wielgosz, Tammi R. A. Kral, David M Perlman et al.
21 citations
OBJECTIVE: Mindfulness-based interventions are widely used to target pain, yet their neural mechanisms of action are insufficiently understood. The authors studied neural and subjective pain response in a randomized active-control trial of mindfulness-based stress reduction (MBSR) alongside long-term meditation practitioners. METHODS: Healthy participants (N=115) underwent functional...
Science Advances
May 20, 2022
Tammi R. A. Kral, Kaley Davis, Cole Korponay et al.
67 citations
Studies purporting to show changes in brain structure following the popular, 8-week mindfulness-based stress reduction (MBSR) course are widely referenced despite major methodological limitations. Here, we present findings from a large, combined dataset of two, three-arm randomized controlled trials with active and waitlist (WL) control groups. Meditation-naïve participants ( n = 218) completed...
International Journal of Psychophysiology
March 28, 2022
Enrico Fucci, Arnaud Poublan-Couzardot, Oussama Abdoun et al.
The auditory mismatch negativity (MMN) is a well characterized event-related potential component which has gained recent attention in theoretical models describing the impact of various styles of mindfulness meditation on attentional processes and perceptual inference. Previous findings highlighted a distinct modulation of the MMN amplitude by different meditation practices and degrees of...
Review of Philosophy and Psychology
2022
Maxwell J D Ramstead, Anil K. Seth, Casper Hesp et al.
75 citations
This paper presents a version of neurophenomenology based on generative modelling techniques developed in computational neuroscience and biology. Our approach can be described as computational phenomenology because it applies methods originally developed in computational modelling to provide a formal model of the descriptions of lived experience in the phenomenological tradition of philosophy...
Neuroscience Letters
November 1, 2021
Prisca R. Bauer, C. Sabourdy, Benoit Chatard et al.
PURPOSE Intracranial electroencephalography (iEEG) offers a unique window on brain dynamics with excellent temporal and spatial resolution and is less prone to recording artefacts than surface EEG. This study used a within-subject design to explore the feasibility to compare iEEG data during mind wandering, mindfulness meditation and hypnosis. RESULTS Three patients who had iEEG for clinical...
Ageing Research Reviews
October 1, 2021
Antoine Lutz, Gaël Chételat, Fabienne Collette et al.
Alzheimer's disease (AD) represents a major health and societal issue; there is no treatment to date and the pathophysiological mechanisms underlying this disease are not well understood. Yet, there is hope that AD risk factors and thus the number of AD cases can be significantly reduced by prevention measures based on lifestyle modifications as targeted by non-pharmacological preventive...
Neuropsychology Review
August 4, 2021
Tim Whitfield, Thorsten Barnhofer, Rebecca L. Acabchuk et al.
193 citations
Mindfulness-based programs (MBPs) are increasingly utilized to improve mental health. Interest in the putative effects of MBPs on cognitive function is also growing. This is the first meta-analysis of objective cognitive outcomes across multiple domains from randomized MBP studies of adults. Seven databases were systematically searched to January 2020. Fifty-six unique studies (n = 2,931) were...
medRxiv
June 16, 2021
Tammi R. A. Kral, Kaley Davis, Cole Korponay et al.
2 citations
preprint
Abstract Studies purporting to show changes in brain structure following the popular, eight-week Mindfulness-Based Stress Reduction (MBSR) course are widely referenced despite major methodological limitations. Here, we present findings from a large, combined dataset of two, three-arm randomized controlled trials with active and waitlist (WL) control groups. Meditation-naive participants (n=218)...
April 13, 2021
Marco Schlosser, Thorsten Barnhofer, Florence Requier et al.
2 citations
Objectives: Deepening our understanding of the mechanisms by which meditation practices impact well-being and human flourishing is essential for advancing the science of meditation. The phenomenologically grounded classification system introduced by Dahl, Lutz, and Davidson (2015) distinguishes attentional, constructive, and deconstructive forms of meditation based on the psychological...
European Journal of Pain
April 2, 2021
Stefano Poletti, Oussama Abdoun, Jelle Zorn et al.
25 citations
BACKGROUND: The way people respond to pain is based on psychological mechanisms, beliefs and expectations. Mindfulness meditation (MM) has been shown to regulate pain and mental suffering through different mechanisms such as positive reappraisal, attentional and emotional regulation. Yet, subjective experience and meaning of pain in connection with MM are still largely unexplored. METHODS: The...
Psychosomatic Medicine
March 31, 2021
Jelle Zorn, Oussama Abdoun, Sandrine Sonié et al.
32 citations
OBJECTIVE: Mindfulness meditation can downregulate the experience of pain. However, its specific underlying regulatory mechanisms are still largely unknown. Here, we aimed to investigate the role of cognitive defusion-a form of psychological distancing from internal experiences-in mindfulness-based pain regulation. METHODS: We implemented a thermal heat paradigm that was designed to amplify the...
Frontiers in Psychology
January 28, 2021
Dylan Thomas Lott, Tenzin Yeshi, N. Norchung et al.
18 citations
Recent EEG studies on the early postmortem interval that suggest the persistence of electrophysiological coherence and connectivity in the brain of animals and humans reinforce the need for further investigation of the relationship between the brain’s activity and the dying process. Neuroscience is now in a position to empirically evaluate the extended process of dying and, more specifically,...
Neuroscience of Consciousness
2021
Lars Sandved-Smith, Casper Hesp, Jérémie Mattout et al.
116 citations
Meta-awareness refers to the capacity to explicitly notice the current content of consciousness and has been identified as a key component for the successful control of cognitive states, such as the deliberate direction of attention. This paper proposes a formal model of meta-awareness and attentional control using hierarchical active inference. To do so, we cast mental action as policy...
Alzheimer s & Dementia
December 1, 2020
Tim Whitfield, Thorsten Barnhofer, Rebecca L. Acabchuk et al.
6 citations
Abstract Background The primary focus of mindfulness‐based program (MBP) research to date has been on mental health. More recently, attention has turned to putative effects on cognition. An evidence synthesis is required to answer the key question of ‘Do MBPs confer cognitive benefit, and if so, for whom?’ A particularly crucial distinction is whether benefits differ according to individuals’...
November 7, 2020
Stefano Poletti, Oussama Abdoun, Jelle Zorn et al.
preprint
Background: The way people respond to pain is based on psychological mechanisms, beliefs and expectations. Mindfulness meditation (MM) has been shown to regulate pain and mental suffering through different mechanisms such as positive reappraisal, attentional and emotional regulation. Yet, subjective experience and meaning of pain in connection with MM are still largely unexplored.Methods: The...
PsyArXiv
June 10, 2020
Lars Sandved-Smith, Casper Hesp, Antoine Lutz et al.
11 citations
preprint
Towards a computational (neuro)phenomenology of mental action: modelling meta-awareness and attentional control with deep-parametric active inference
European Journal of Pain
April 20, 2020
Jelle Zorn, Oussama Abdoun, Romain Bouet et al.
55 citations
BACKGROUND: Mindfulness meditation can alleviate acute and chronic pain. It has been proposed that mindfulness meditation reduces pain by uncoupling sensory and affective pain dimensions. However, studies to date have reported mixed results, possibly due to a diversity of styles of and expertise in mindfulness meditation. Furthermore, the interrelations between mindfulness meditation and pain...
European Journal of Neuroscience
December 2, 2019
Constanza Baquedano, Vladimir Lopez, Diego Cosmelli et al.
8 citations
Awareness of mental events as mere representations rather than as accurate depictions of reality, also known as dereification, is one of the key features of mindfulness meditation. Dereification is juxtaposed to subjective realism, the process of being lost or totally immersed in the contents of one's mind. Excessive subjective realism is a hallmark of several psychiatric disorders. Here, we...
Scientific Reports
August 19, 2019
Cole Korponay, Daniela Dentico, Tammi R. A. Kral et al.
49 citations
Interest has grown in using mindfulness meditation to treat conditions featuring excessive impulsivity. However, while prior studies find that mindfulness practice can improve attention, it remains unclear whether it improves other cognitive faculties whose deficiency can contribute to impulsivity. Here, an eight-week mindfulness intervention did not reduce impulsivity on the go/no-go task or...