Psychosomatic Medicine
October 1, 2024
J Richard T Korecki, Patricia A Ganz, Ann H Partridge et al.
2 citations
Depression is associated with poor outcomes in breast cancer patients, with higher prevalence among younger women. Although mindfulness-based interventions (MBIs) have demonstrated therapeutic effects, the mechanisms of intervention effects are poorly understood. We investigated whether rumination, self-kindness, intrusive thoughts about cancer, cancer-related worry, or a sense of meaning and...
Psychosomatic Medicine
2024
Rachel Churchill, Brenda Swartz, Anneka Johnston-Dumerauf et al.
4 citations
Autonomic dysregulation is common in many medical conditions and can have a widespread, negative impact on multiple bodily systems, leading to poorer health outcomes. Thus, addressing autonomic dysregulation as part of a comprehensive treatment plan is important. The goal of this study was to gain a better understanding of the physiological benefits of a mindfulness-based intervention (MBI) for...
Psychosomatic Medicine
May 5, 2021
Thorsten Barnhofer, Tim Jonas Reeß, Maria Fißler et al.
24 citations
OBJECTIVE: Mindfulness-based interventions (MBIs) have been found to be a promising approach for the treatment of recurrent courses of depression. However, little is known about their neural mechanisms. This functional magnetic resonance imaging study set out to investigate activation changes in corticolimbic regions during implicit emotion regulation. METHODS: Depressed patients with a...
Psychosomatic Medicine
March 31, 2021
Jelle Zorn, Oussama Abdoun, Sandrine Sonié et al.
32 citations
OBJECTIVE: Mindfulness meditation can downregulate the experience of pain. However, its specific underlying regulatory mechanisms are still largely unknown. Here, we aimed to investigate the role of cognitive defusion-a form of psychological distancing from internal experiences-in mindfulness-based pain regulation. METHODS: We implemented a thermal heat paradigm that was designed to amplify the...
Psychosomatic Medicine
March 3, 2021
Emily K. Lindsay, J. David Creswell, Harrison J. Stern et al.
18 citations
OBJECTIVE: Mindfulness interventions have been effective for improving a range of health outcomes; however, pathways underlying these effects remain unclear. Inflammatory processes may play a role, possibly through increased resistance of immune cells to the anti-inflammatory effects of glucocorticoids (i.e., glucocorticoid resistance, or GCR). Here, we conducted an initial examination of...
Psychosomatic Medicine
April 1, 2019
J. D. Creswell, Emily K. Lindsay, Daniella K. Villalba et al.
Objective There has been substantial research and public interest in mindfulness interventions, biological pathways, and health for the past two decades. This article reviews recent developments in understanding relationships between mindfulness interventions and physical health. Methods A selective review was conducted with the goal of synthesizing conceptual and empirical relationships...
Psychosomatic Medicine
April 11, 2018
Gunes Sevinc, Britta K. Hölzel, Javeria A. Hashmi et al.
65 citations
OBJECTIVE: We investigated common and dissociable neural and psychological correlates of two widely used meditation-based stress reduction programs. METHODS: Participants were randomized to the Relaxation Response (RR; n = 18; 56% female) or the Mindfulness-Based Stress Reduction (MBSR; n = 16; 56% female) programs. Both programs use a "bodyscan" meditation; however, the RR program explicitly...
Psychosomatic Medicine
March 22, 2017
Adrienne A. Taren, Peter J. Gianaros, Carol M. Greco et al.
212 citations
OBJECTIVE: Mindfulness meditation training has been previously shown to enhance behavioral measures of executive control (e.g., attention, working memory, cognitive control), but the neural mechanisms underlying these improvements are largely unknown. Here, we test whether mindfulness training interventions foster executive control by strengthening functional connections between dorsolateral...
Psychosomatic Medicine
November 1, 2011
R. Gina Silverstein, Anne-Catharine H. Brown, Harold D. Roth et al.
165 citations
OBJECTIVES: Treatments of female sexual dysfunction have been largely unsuccessful because they do not address the psychological factors that underlie female sexuality. Negative self-evaluative processes interfere with the ability to attend and register physiological changes (interoceptive awareness). This study explores the effect of mindfulness meditation training on interoceptive awareness...
Psychosomatic Medicine
July 1, 2007
J. David Creswell, Baldwin M. Way, Naomi I. Eisenberger et al.
840 citations
OBJECTIVE: Mindfulness is a process whereby one is aware and receptive to present moment experiences. Although mindfulness-enhancing interventions reduce pathological mental and physical health symptoms across a wide variety of conditions and diseases, the mechanisms underlying these effects remain unknown. Converging evidence from the mindfulness and neuroscience literature suggests that...
Psychosomatic Medicine
2004
Richard J. Davidson, Jon Kabat‐zinn
35 citations
University of Wisconsin Madison, Wisconsin University of Massachusetts Medical School Amherst, Massachusetts
Psychosomatic Medicine
July 1, 2003
Richard J. Davidson, Jon Kabat‐zinn, Jessica R. Schumacher et al.
2,924 citations
OBJECTIVE: The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored. We performed a randomized, controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work...
Psychosomatic Medicine
July 1, 2003
Linda E. Carlson, Michael Speca, Kamala D. Patel et al.
773 citations
OBJECTIVES: This study investigated the relationships between a mindfulness-based stress reduction meditation program for early stage breast and prostate cancer patients and quality of life, mood states, stress symptoms, lymphocyte counts, and cytokine production. METHODS: Forty-nine patients with breast cancer and 10 with prostate cancer participated in an 8-week MBSR program that incorporated...
Psychosomatic Medicine
2002
Scott R. Bishop
759 citations
OBJECTIVE: Mindfulness-Based Stress Reduction (MBSR) is a clinical program, developed to facilitate adaptation to medical illness, which provides systematic training in mindfulness meditation as a self-regulatory approach to stress reduction and emotion management. There has been widespread and growing use of this approach within medical settings in the last 20 years, and many claims have been...
Psychosomatic Medicine
September 1, 2000
Michael Speca, Linda E. Carlson, Eileen Goodey et al.
1,091 citations
OBJECTIVE: The objective of this study was to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients. METHODS: A randomized, wait-list controlled design was used. A convenience sample of eligible cancer patients enrolled after giving informed consent and were randomly assigned to either an...
Psychosomatic Medicine
1998
Robert H Schneider, Sanford Nidich, John Salerno et al.
95 citations
OBJECTIVE: Oxidative stress or free radical activity may contribute to the pathophysiology of atherosclerosis and other chronic diseases associated with aging. Because psychosocial stress has been shown to increase oxidative stress, we conducted an exploratory study to investigate the effects of stress reduction with the Transcendental Meditation program on serum lipid peroxide levels in...
Psychosomatic Medicine
May 1, 1984
Kheireddine Badawi, Robert K. Wallace, David W. Orme-Johnson et al.
91 citations
In a study designed to identify the electrophysiologic characteristics of the Transcendental Meditation Program, 52 periods of spontaneous respiratory suspension (RS) were observed in 18 subjects during the practice of this program. These periods were correlated with some but not all the subjective experiences of pure consciousness. Nineteen RS periods (belonging to 11 subjects) free from any...
Psychosomatic Medicine
May 1, 1982
John T. Farrow, Russell Hebert
95 citations
We observed, over four independent experiments, 565 criterion-meeting episodes of breath suspension in 40 subjects practicing the Transcendental Mediation technique (TM), a simple mental technique involving no breath control procedures. The frequency and length of these breath suspension episodes were substantially and significantly greater for TM subjects than for control subjects relaxing...
Psychosomatic Medicine
February 1, 1979
Ruth R. Michaels, Juan Parra, Daisy S. McCann et al.
54 citations
The effects of transcendental meditation (TM) on plasma renin activity (PRA) and plasma concentrations of aldosterone, cortisol, and lactate were studied by measuring these variables before, during, and after 20--30 min of meditation. Subjects, who rested quietly rather than meditating, served as controls. There were no differences in the basal values for these variables between meditators and...
Psychosomatic Medicine
June 1, 1978
Gary E. Schwartz, Richard J. Davidson, Daniel J. Goleman
398 citations
Davidson and Schwartz (1) have proposed a psychobiological analysis of anxiety that emphasizes the patterning of multiple processes in the generation and self-regulation of this state. The present article specifically reviews recent research on cognitive and somatic components of anxiety. A dual component scale which separately assesses cognitive and somatic trait anxiety is described and...
Psychosomatic Medicine
July 1, 1973
David W. Orme-Johnson
20 citations
Physiological indices of stress were found to be lower in people who regularly practiced Transcendental Meditation (N=14) than in nonmeditating control subjects (N=16). During normal waking (eyes open) a noxious loud tone (100 db, 0.5 sec, 3000 Hz) was presented to subjects a mean of once every 53 sec at irregular intervals. The stress reaction to each tone, as indicated by the galvanic skin...
Psychosomatic Medicine
September 1, 1962
Ralph J. Kahana
2 citations
The psychotherapy of a man with ulcerative colitis is reported in which a psychological crisis preceded remission of bowel dysfunction. This turning point featured hypnagogic hallucinations and dreams, including phenomena reported by Isakower, Lewin, Rycroft, and others. The deeper psychological meaning of the illness and the crisis is seen as the patient's attempt to incorporate a constant,...
Psychosomatic Medicine
October 1, 1942
Morton A. Rubin, William Malamud, Justin M. Hope
24 citations
Mescaline, cocaine, sodium amytal and benzedrine were given to 14 schizophrenic patients, and their influence upon personality functions and the electroencephalogram (EEG) was observed. Changes in the EEG were found only when definite psychological changes took place. The effects of the drugs could be classified into two types: 1) Those specific for a given drug. Psychologically these were...
Psychosomatic Medicine
Eileen Luders, Felipe A Jain, Florian Kurth
A growing body of scientific evidence suggests that meditation may slow brain aging. The amygdala-a heterogenous brain region known to decrease in volume with increasing age-seems to be involved in meditation and affected by meditation. Thus, we hypothesized that the age-related decline of the amygdala is diminished in meditation practitioners. We investigated whether correlations between age...