Supportive Care in Cancer
October 2016
Patricia A Poulin, Heather Romanow, Noriyeh Rahbari et al.
This study aims to examine if mindfulness is associated with pain catastrophizing, depression, disability, and health-related quality of life (HRQOL) in cancer survivors with chronic neuropathic pain (CNP). We conducted a cross-sectional survey with cancer survivors experiencing CNP. Participants (n = 76) were men (24 %) and women (76 %) with an average age of 56.5 years (SD = 9.4)....
Australian & New Zealand Journal of Psychiatry
October 2016
Frances Shawyer, Joanne Enticott, Mehmet Özmen et al.
While mindfulness-based cognitive therapy is effective in reducing depressive relapse/recurrence, relatively little is known about its health economic properties. We describe the health economic properties of mindfulness-based cognitive therapy in relation to its impact on depressive relapse/recurrence over 2 years of follow-up. Non-depressed adults with a history of three or more major...
Scandinavian Journal of Psychology
October 2016
Josefine L Lilja, Clara Zelleroth, Ulf Axberg et al.
This study examined the effectiveness of mindfulness-based cognitive therapy (MBCT) in primary care for patients with recurrent depression (major depressive disorder: MDD). According to the World Health Organization (WHO), MDD is now the leading cause of disease burden in middle- and high-income countries. Patients (N = 45) with three or more previous depressive episodes were recruited to...
Behavioural Brain Research
October 1, 2016
Connor Thelen, Jonathon Sens, Joseph Mauch et al.
One of the most striking discoveries in the treatment of major depression was the finding that infusion of a single sub-anesthetic dose of ketamine induces rapid and sustained antidepressant effects in treatment-resistant depressed patients. However, ketamine's antidepressant-like actions are transient and can only be sustained by repeated drug treatment. Despite the fact that women experience...
Medicinski pregled
October 2016
Dušan Kolar, Michael V Kolar
Treatment-resistant mood and anxiety disorders require an intensive therapeutic approach, and it should balance benefits and adverse effects or other potential detrimental effects of medications. The goal of treatment is to provide consistent and lasting improvement in symptoms of depression and anxiety. Beozodiazepines are effective for anxiety symptoms, but with no sustained treatment...
Schizophrenia Research
October 2016
Vina M Goghari, Martin Harrow
Hallucinations are a salient feature of both psychotic and mood disorders. Currently there is a call for more research on the phenomenology of different forms of hallucinations, in a broader array of disorders, to further both theoretical knowledge and clinical utility. We investigated auditory, visual, and olfactory hallucinations at index hospitalization and auditory and visual hallucinations...
Journal of Evidence-Based Complementary & Alternative Medicine
September 30, 2016
Tamara L Goldsby, Michael E Goldsby, Mary McWalters et al.
Poor mood and elevated anxiety are linked to increased incidence of disease. This study examined the effects of sound meditation, specifically Tibetan singing bowl meditation, on mood, anxiety, pain, and spiritual well-being. Sixty-two women and men (mean age 49.7 years) participated. As compared with pre-meditation, following the sound meditation participants reported significantly less...
Psychiatria i Psychologia Kliniczna
September 30, 2016
Karolina Dydak, Mariola Śliwińska‐mossoń, Halina Milnerowicz
2 citations
Psylocybina jest substancją psychodysleptyczną pochodzenia naturalnego, występuje w grzybach rodzaju Psilocybe. Psychodysleptyki są środkami psychoaktywnymi, które silnie wpływają na percepcję, nastrój i procesy poznawcze człowieka. Psychodeliczne działanie psylocybiny opiera się na pobudzaniu receptorów serotoninergicznych, co prowadzi do wzrostu stężenia serotoniny w mózgu oraz przyczynia się...
International Journal of Indian Psychology
September 25, 2016
Depression is the common cold of mental disorders. It is one of the main issues that needs to receive a great deal of attention in order to create grounds to be prevented or cured. It is interesting to note that there is extensive literature emphasising the role and effectiveness of CBT as the treatment of depression. But few researchers talk about combined effect of CBT and Mindfulness. So to...
Complementary Therapies in Clinical Practice
September 22, 2016
Laura Tolbaños-roche, María Teresa Miró Barrachina, Ignacio Ibáñez Fernández
Objective: To analyze the effect of the 'Exercise Without Movement' (E.W.M) yoga method on mindfulness and on the improvement of anxiety and depression symptoms. Methods: A quasi-experimental study examined the effect of one month E.W.M. intervention among 38 participants who were enrolled voluntarily to both groups, study (n = 16) and control (n = 22). Five participants dropped out during the...
World Psychiatry
September 22, 2016
Zindel V. Segal, Lê-Anh Dinh-Williams
11 citations
Relapse and recurrence are common and debilitating aspects of major depressive disorder. Furthermore, the risk of developing a chronic course of illness increases with each successive episode and, even among patients who achieve clinical remission, residual depressive symptoms are commonly reported. Maintenance antidepressant monotherapy is effective as long as it is continued, yet in practice...
Translational Psychiatry
September 20, 2016
Daniel M. Rotroff, Daniel Corum, Alison A. Motsinger‐Reif et al.
99 citations
Ketamine, at sub-anesthetic doses, is reported to rapidly decrease depression symptoms in patients with treatment-resistant major depressive disorder (MDD). Many patients do not respond to currently available antidepressants, (for example, serotonin reuptake inhibitors), making ketamine and its enantiomer, esketamine, potentially attractive options for treatment-resistant MDD. Although...
PSYCH up2date
September 8, 2016
Fazit Die vorliegende Studie gibt erste Hinweise auf eine Wirksamkeit von Psilocybin bei chronischen Depressionen. Weitere positive Effekte dieser Substanz konnten bereits in anderen Zusammenhängen nachgewiesen werden. Bei nun nachgewiesener, guter Machbarkeit, motivieren die Autoren zu weiteren kontrollierten Studien mit diesem Wirkstoff.
Contemporary Clinical Trials
September 2016
Rhoda Schuling, Marloes J. Huijbers, Hiske Van Ravesteijn et al.
Mindfulness Based Cognitive Therapy (MBCT) has been shown to reduce the risk of relapse in patients with recurrent depression, but relapse rates remain high. To further improve outcome for this group of patients, follow-up interventions may be needed. Compassion training focuses explicitly on developing self-compassion, one of the putative working mechanisms of MBCT. No previous research has...
Journal of Affective Disorders
September 1, 2016
Xiaomei Zhong, Hongbo He, Chunping Zhang et al.
Treatment-resistant depression (TRD) is a growing clinical challenge. Electroconvulsive therapy (ECT) is an effective tool for TRD treatment. However, there remains a subset of patients who do not respond to this treatment with common anesthetic agent. Ketamine, a noteworthy anesthetic agent, has emerged as an augmentation to enhance the antidepressant efficacy of ECT. Trials of i.v. ketamine...
Psychopharmacology
September 2016
Jen-Cheng Lin, Mei-Yi Lee, Ming‐huan Chan et al.
Ketamine is emerging as a new hope against depression, but ketamine-associated psychotomimetic effects limit its clinical use. An adjunct therapy along with ketamine to alleviate its adverse effects and even potentiate the antidepressant effects might be an alternative strategy. Betaine, a methyl derivative of glycine and a dietary supplement, has been shown to have antidepressant-like effects...
Military Medicine
September 1, 2016
Marina A Khusid, Meena Vythilingam
Mindfulness-based interventions (MBIs) have been increasingly utilized in the management of mental health conditions. This first review of a two-part series evaluates the efficacy, mechanism, and safety of mindfulness meditation for mental health conditions frequently seen after return from deployment. Standard databases were searched until August 4, 2015. 52 systematic reviews and randomized...
The Journal of ECT
September 1, 2016
Janusz Rybakowski, Anna Bodnar, Milosz Krzywotulski et al.
39 citations
Objectives Electroconvulsive therapy (ECT) is the most effective treatment for drug-resistant depression (DRD). Because a single infusion of ketamine may exert both a rapid antidepressant effect and a quick improvement of cognition, the aim of the present study was to assess whether ketamine, as an anesthetic drug for ECT, can augment the antidepressant activity of the procedure and/or exert a...
Journal of Caring Sciences
August 31, 2016
Reza Yazdanimehr, A. Omidi, Z. Sadat et al.
Introduction: Pregnancy can be associated with different psychological problems such as depression and anxiety. These problems are often neglected and left untreated. This study aimed to examine the effect of mindfulness-integrated cognitive behavior therapy on depression and anxiety among pregnant women. Methods: A convenient sample of 80 pregnant women were selected. Participants were...
The Primary Care Companion For CNS Disorders
August 25, 2016
Robert G. Bota, Jessica Hazen, Ryan Tieu et al.
To determine if the use of mindfulness-based cognitive therapy (MBCT) in patients with a history of 2 or more episodes of major depressive disorder and other mood disorders will decrease the need for medication management and other interventions and will also decrease the need for outpatient services and the overall cost of treatment. The study patients completed MBCT group sessions between...